Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables serine-type endopeptidase inhibitor activity and signaling receptor binding activity. Involved in negative regulation of plasminogen activation and negative regulation of platelet aggregation. Acts upstream of or within several processes, including modulation of chemical synaptic transmission; negative regulation of signal transduction; and nervous system development. Located in extracellular region and neuromuscular junction. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; musculoskeletal system; and reproductive system. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human SERPINE2 (serpin family E member 2).