Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable receptor ligand activity. Involved in several processes, including CD40 signaling pathway; positive regulation of non-canonical NF-kappaB signal transduction; and toll-like receptor 3 signaling pathway. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; positive regulation of T cell proliferation; and toll-like receptor signaling pathway. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Is expressed in central nervous system; mandible; and retina. Used to study Guillain-Barre syndrome. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; autoimmune disease (multiple); chronic lymphocytic leukemia; chronic obstructive pulmonary disease; and systemic scleroderma. Orthologous to human CD86 (CD86 molecule).