MGI 5.12 Find Mutations Causing a Combination of Phenotypes

How do I find mutations that cause a specific combination of phenotypes?

Overview

You can use the Phenotypes, Alleles and Disease Models Query Form to find alleles of a gene, alleles associated with a specific phenotype, or alleles created by a specific type of mutation.

Accessing the Phenotypes, Alleles and Disease Models Query Form

On most MGI pages, you can access the Phenotypes, Alleles and Disease Models Query Form from the Search menu as shown in the image at right.

For this tutorial, open the Phenotypes, Alleles and Disease Models Query Form in a new window. Scroll down this page for further instructions.

Example 1. Finding alleles associated with both hyperglycemia AND glucosuria

Type hyperglycemia AND glucosuria in the Phenotype/Disease text box. Searches can be restricted to a defined genetic region if desired.
Click Search.

Click on an allele symbol in the first column of the search results to view greater detail about the selected allele, including descriptions of phenotypes, mouse genetic background and any associated diseases. Note that the precise search terms entered may not appear in the phenotype descriptions for an allele. These search terms may have been captured as synonyms during the search, and be represented by different terms than those originally entered.