How do I find existing recombinase-expressing transgenes/knock-ins that have a given promoter (driver)?
Find Recombinase-Carrying Alleles

On most MGI pages, you can access the Recombinase (cre) Activity page from the Search menu as shown in the image at right. From the homepage, you can also access this page by clicking on the "Recombinases (cre)" header or icon.

For this tutorial, open the Recombinase (cre) Activity page in a new window. Scroll down this page for further instructions.

The Access Data section allows you to search for recombinase expression in a specified tissue or under the control of a given gene.

Search Menu

Example 1. Finding a transgene expressing recombinase under the control of Nes.
  1. Select Nes from the Recombinase driven by selection list.

  2. Click Go.
Recombinase driven by
  1. In the summary page that appears, click the link to phenotype data below an allele symbol to go to the detail page for more information. By default, alleles are listed alphabetically according to Allele Symbol, but clicking the column headers will re-sort the table.

      - To obtain commercially available mice carrying this transgene, follow the hyperlinked numbers in the Find Mice (IMSR) column indicated with an arrow which will link out to the International Mouse Strain Resource.

Nes Allele results summary
  1. On the Transgene Detail page, go to the Recombinase activity section and click one of the anatomical systems for more information (see below). Toggle the arrow in the Transgene Description row to expand the genetic details.
Nes Allele Recombinase Specificity
  1. Within the Recombinase Activity Detail page, you can find links to comprehensive data on recombinase gene expression and activity. You can also easily locate:

      (a) links to other cre alleles with activity in the selected tissue or organ
      (b) dynamic figures displaying experimental reporter data for the allele
      (c) level of cre activity within a given tissue or organ


    Sort the table by clicking on column headers.
Nes Allele Recombinase Activity