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Inbred Strains of Rats: R

R

Inbr. F78.

Colour: Albino.

Genet. c.

Origin: Muhlbock from a Wistar stock in 1947. A congenic strain with hyperbilirubinaemia and jaundice has been developed by Leyten et al (1986) by backcrossing the jaundice gene j (the Gunn rat) onto strain R.

Leyten R., Vroemen J. P. A. M., Blanckaert N., and Heirwegh K. P. M. (1986) The congenic normal R/Apfd and jaundiced R/Apfd-j/j rat strains - a new animal-model of hereditary non-hemolytic unconjugated hyperbilirubinemia due to defective bilirubin conjugation. Lab. Anim. 20, 335-342. \par

INBRED STRAINS OF RATS
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK
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