ODUS

Inbr. F42.

Colour: Albino \par

Genet. c.

Origin: As for ODU, but maintained at Osaka Dental University.

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Characteristics

Rats exhibit markedly heavy plaque formation on the lower incisors and develop both periodontal pocket and gingivitis after being fed with a commercial powdered diet (Shinohara et al 1991). Pocket depth was correlated with the amount of salivary sialic acid in pilocarpine-stimulated saliva, but not with serum sialic acid (Shinohara et al, 1994).

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Shinohara M., Ohura K., Ogata K., and Mori M. (1991) A new rat strain with naturally occurrindg gingivitis, "ODUS/Odu2". Rat News Lett. 24, 4-6. \par

Shinohara M., Ohura K., Ogata K., Inoue H., Miyata T., and Yoshioka M. (1994) The relationship between the sialic-acid concentrations in the serum and whole saliva in rats with naturally-occurring gingivitis. Jpn. J. Pharmacol. 64, 61-63. \par

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INBRED STRAINS OF RATS
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK