MLCS

Inbr. F?+N8.

Colour: Albino.

Genet. c.

Origin: From a cross between MHS and MNS followed by backcrossing to MNS with selection for low calpastatin activity.

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Characteristics

Has normal blood pressure and low calpastatin activity, and is proposed as a model for the study of the calpain-calpastatin system (Soldati et al, 1995)

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Soldati L. P., Barber B. R., Salardi S., Molinari I., and Bianchi G. (1995) A new rat model for studying the calpain-calpastatin system. Lab. Anim. 29, 420-426.

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INBRED STRAINS OF RATS
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK