FCH (Reserved symbol)

Inbr. F15 (1989).

Origin: "Fice Combined Hyperlipidemic strain". Strain developed from outbred stock by selection for high serum cholesterol.

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Characteristics

Now has 212_58 mg/dl total serum cholesterol compared with 47_5 mg/dl in low cholesterol strain FNL. Develops chronic progressive nephrosis and hyperproteinuria from about 3 months of age (Patrono et al 1989).

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Patrono C., Ghiselli G., Lovisolo P. P. S. P., and Barber B. R. (1989) Contribution. Rat News Lett. 22, 17-18.

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INBRED STRAINS OF RATS
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK