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Inbred Strains of Rats: DEBR

DEBR Reserved symbol.

Inbr. >F15.

Colour: Hooded.

Genet. ?

Origin: Dr. Roy F. Oliver, Dept. of Biological Sciences, University of Dundee. A possible animal model for human alopecia areata, with hair loss associated with marked peri-and intra-bulbar lymphocytic infiltrate (Michie et al 1991, Sainsbury et al, 1991, Oliver et al, 1991).


Michie hj, Jahoda C. A. B., Oliver R. F., and Johnson B. E. (1991) The DEBR rat- an animal model of human alopecia areata. Brit. J. Dermatol. 125, 94-100. \par

Oliver R. F., Jahoda C. A. B., Horne K. A., Michie H. J., Poulton T., and Johnson B. E. (1991) The DEBR rat model for alopecia-areata. J. Invest. Dermatol. 96, S97. \par

Sainsbury T. S. L., Duncan J. I., Whiting P. H., Hewick D. S., Johnson B. E., Thomson A. W., and Oliver R. F. (1991) Differential effects of FK-506 and cyclosporine on hair regrowth in the DEBR model of alopecia-areata. Transplant. Proc. 23, 3332-3334. \par


INBRED STRAINS OF RATS
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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