MGI - Inbred Strains: DEBR

Inbred Strains of Rats: DEBR

DEBR Reserved symbol.

Inbr. >F15.

Colour: Hooded.

Genet. ?

Origin: Dr. Roy F. Oliver, Dept. of Biological Sciences, University of Dundee. A possible animal model for human alopecia areata, with hair loss associated with marked peri-and intra-bulbar lymphocytic infiltrate (Michie et al 1991 , Sainsbury et al, 1991 , Oliver et al, 1991).

Michie hj, Jahoda C. A. B., Oliver R. F., and Johnson B. E. (1991) The DEBR rat- an animal model of human alopecia areata. Brit. J. Dermatol. 125, 94-100.

Oliver R. F., Jahoda C. A. B., Horne K. A., Michie H. J., Poulton T., and Johnson B. E. (1991) The DEBR rat model for alopecia-areata. J. Invest. Dermatol. 96, S97.

Sainsbury T. S. L., Duncan J. I., Whiting P. H., Hewick D. S., Johnson B. E., Thomson A. W., and Oliver R. F. (1991) Differential effects of FK-506 and cyclosporine on hair regrowth in the DEBR model of alopecia-areata. Transplant. Proc. 23, 3332-3334.

INBRED STRAINS OF RATS
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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