Compare GO annotations for ORTHOMCL839 PPOD cluster

Possible outliers might be spotted in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, zfish, fly, worm, dicty, dicot, yeast, pombe, ecoli.
Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Red arrows indicate "regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Zfish from Zfin; Fly from Flybase; Worm from Wormbase; Dicot from TAIR; Dicty from Dictybase; Yeast from SGD; Pombe from Sanger; Ecoli from EcoliHub.
Organisms with experimental annotations are indicated: EXP, IC, IDA, IEP, IGI, IMP, IPI. In addition, ISS (ISA, ISM, ISO) annotations are so indicated.
Does not include evidence codes: IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Mon Mar 30 18:25:07 2009.

Compare annotations to GO categories for ORTHOMCL839.

Entry indicates that ortholog exists for this gene.
Colored entries indicate experimental annotation.
Parentheses indicate ISS annotation only.

Category	ID	Term	Human	Mouse	Rat	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli
Molecular Function	GO:0005488	binding	Human	(Mouse)	Rat	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli
Molecular Function	GO:0003824	catalytic activity	Human	Mouse	Rat	Chicken	Zfish	(Fly)	Worm	(Dicty)	Dicot	Yeast	(Pombe)	Ecoli
Cellular Component	GO:0005623	cell	Human	Mouse	Rat	Chicken	Zfish	(Fly)	Worm	(Dicty)	Dicot	Yeast	Pombe	Ecoli
Cellular Component	GO:0044464	cell part	Human	Mouse	Rat	Chicken	Zfish	(Fly)	Worm	(Dicty)	Dicot	Yeast	Pombe	Ecoli
Cellular Component	GO:0031975	envelope	Human	Mouse	(Rat)	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli
Cellular Component	GO:0031974	membrane-enclosed lumen	Human	Mouse	Rat	Chicken	Zfish	(Fly)	Worm	Dicty	Dicot	Yeast	(Pombe)	Ecoli
Cellular Component	GO:0043226	organelle	Human	Mouse	Rat	Chicken	Zfish	(Fly)	Worm	(Dicty)	Dicot	Yeast	Pombe	Ecoli
Cellular Component	GO:0044422	organelle part	Human	Mouse	(Rat)	Chicken	Zfish	(Fly)	Worm	Dicty	Dicot	Yeast	(Pombe)	Ecoli
Biological Process	GO:0065007	biological regulation	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli
Biological Process	GO:0009987	cellular process	(Human)	Mouse	(Rat)	Chicken	Zfish	(Fly)	Worm	(Dicty)	Dicot	Yeast	(Pombe)	Ecoli
Biological Process	GO:0032502	developmental process	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli
Biological Process	GO:0002376	immune system process	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli
Biological Process	GO:0008152	metabolic process	(Human)	Mouse	(Rat)	Chicken	Zfish	(Fly)	Worm	(Dicty)	Dicot	Yeast	(Pombe)	Ecoli
Biological Process	GO:0032501	multicellular organismal process	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli
Biological Process	GO:0050789	regulation of biological process	Human	Mouse	Rat	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli
Biological Process	GO:0050896	response to stimulus	Human	Mouse	Rat	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli

Full set of experimental (and ISS) annotations for ORTHOMCL839

Category	ID	Term	DB Object	Evidence	With_From	Organism	Reference
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	P22557	IDA		Human	PMID:14643893
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	Alas2	IMP		Mouse	MGI:MGI:75768\|PMID:7620186
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	Alas2	ISO	EMBL:AF068624	Mouse	MGI:MGI:2154458
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	Alas1	IDA		Rat	RGD:632013\|PMID:3182776
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	Alas2	IDA		Rat	RGD:632181\|PMID:8407861
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	Alas2	IDA		Rat	RGD:1581096\|PMID:15181459
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	Alas2	ISS	UniProtKB:P22557	Rat	RGD:1600115
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	Alas2	ISO	RGD:732282	Rat	RGD:1624291
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	Alas1	IDA		Rat	RGD:1601233\|PMID:16125296
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	Alas2	ISO	RGD:736755	Rat	RGD:1624291
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	Alas	ISS	SGD:S0002640	Fly	FB:FBrf0105495
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	Alas	ISS	RGD:2084	Fly	FB:FBrf0123179\|PMID:10601299
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	Alas	ISS	UniProtKB:P13196	Fly	FB:FBrf0159903
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	Alas	ISS	UniProt:P22557	Fly	FB:FBrf0159903
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	hemA	ISS	SGD:S000002640	Dicty	dictyBase_REF:10155
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	HEM1	IMP		Yeast	SGD_REF:S000057328\|PMID:7035824
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	hem1	ISS	UniProtKB:P09950	Pombe	PMID:17072883
Molecular Function	GO:0050662	coenzyme binding	Alas2	IDA		Rat	RGD:632181\|PMID:8407861
Molecular Function	GO:0016594	glycine binding	Alas2	IDA		Rat	RGD:632181\|PMID:8407861
Molecular Function	GO:0008890	glycine C-acetyltransferase activity	CG10361	ISS	UniProtKB:O88986	Fly	FB:FBrf0105495
Molecular Function	GO:0008890	glycine C-acetyltransferase activity	CG10361	ISS	UniProtKB:O75600	Fly	FB:FBrf0159903
Molecular Function	GO:0020037	heme binding	Alas2	ISS	MGI:87990	Rat	RGD:15496594
Molecular Function	GO:0005515	protein binding	P22557	IPI	UniProtKB:Q9P2R7	Human	PMID:10727444
Molecular Function	GO:0005515	protein binding	P22557	IPI	UniProtKB:P40337	Human	PMID:16234850
Molecular Function	GO:0005515	protein binding	P22557	IPI	UniProtKB:Q9P2R7	Human	PMID:14643893
Molecular Function	GO:0005515	protein binding	Alas2	ISO	EMBL:AF068624	Mouse	MGI:MGI:2154458
Molecular Function	GO:0005515	protein binding	Alas2	ISS	UniProtKB:P22557	Rat	RGD:1600115
Molecular Function	GO:0005515	protein binding	Alas2	ISO	RGD:736755	Rat	RGD:1624291
Molecular Function	GO:0008483	transaminase activity	hem1	ISS	Pfam:PF00155	Pombe	PMID:17072883
Cellular Component	GO:0005743	mitochondrial inner membrane	P22557	IDA		Human	PMID:14643893
Cellular Component	GO:0005743	mitochondrial inner membrane	Gcat	IDA		Mouse	MGI:MGI:3590069\|PMID:12865426
Cellular Component	GO:0005743	mitochondrial inner membrane	Alas2	ISO	RGD:736755	Rat	RGD:1624291
Cellular Component	GO:0005743	mitochondrial inner membrane	Alas2	ISS	UniProtKB:P22557	Rat	RGD:1600115
Cellular Component	GO:0005743	mitochondrial inner membrane	Gcat	ISO	RGD:1316397	Rat	RGD:1624291
Cellular Component	GO:0005759	mitochondrial matrix	Alas	ISS	UniProtKB:P13196	Fly	FB:FBrf0159903
Cellular Component	GO:0005759	mitochondrial matrix	Alas	ISS	UniProt:P22557	Fly	FB:FBrf0159903
Cellular Component	GO:0005759	mitochondrial matrix	HEM1	IDA		Yeast	SGD_REF:S000054004\|PMID:3023841
Cellular Component	GO:0005759	mitochondrial matrix	hem1	ISS	UniProtKB:P09950	Pombe	PMID:17072883
Cellular Component	GO:0005739	mitochondrion	P22557	IDA		Human	PMID:10727444
Cellular Component	GO:0005739	mitochondrion	Alas2	ISO	EMBL:AF068624	Mouse	MGI:MGI:2154458
Cellular Component	GO:0005739	mitochondrion	Alas2	IDA		Mouse	MGI:MGI:2682130\|PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Gcat	IDA		Mouse	MGI:MGI:2682130\|PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Alas2	ISO	RGD:736755	Rat	RGD:1624291
Cellular Component	GO:0005739	mitochondrion	Alas2	IDA		Rat	RGD:15496594
Cellular Component	GO:0005739	mitochondrion	Alas2	ISS	UniProtKB:P22557	Rat	RGD:1600115
Cellular Component	GO:0005739	mitochondrion	Alas2	ISO	RGD:732282	Rat	RGD:1624291
Cellular Component	GO:0005739	mitochondrion	Gcat	ISO	RGD:1316397	Rat	RGD:1624291
Cellular Component	GO:0005739	mitochondrion	Alas2	IDA		Rat	RGD:1581087\|PMID:15496594
Cellular Component	GO:0005739	mitochondrion	CG10361	ISS	UniProtKB:O75600	Fly	FB:FBrf0159903
Cellular Component	GO:0005739	mitochondrion	hemA	ISS	SGD:S000002640	Dicty	dictyBase_REF:10155
Cellular Component	GO:0005739	mitochondrion	HEM1	IDA		Yeast	SGD_REF:S000117178\|PMID:16823961
Cellular Component	GO:0005739	mitochondrion	hem1	IDA		Pombe	PMID:16823372
Cellular Component	GO:0005625	soluble fraction	Alas2	IDA		Rat	RGD:15496594
Biological Process	GO:0006520	amino acid metabolic process	CG10361	ISS	UniProtKB:O75600	Fly	FB:FBrf0159903
Biological Process	GO:0006879	cellular iron ion homeostasis	Alas2	IMP	MGI:MGI:2180151	Mouse	MGI:MGI:1347738\|PMID:10562540
Biological Process	GO:0006879	cellular iron ion homeostasis	Alas2	ISO	RGD:732282	Rat	RGD:1624291
Biological Process	GO:0035162	embryonic hemopoiesis	alas2	IMP	ZFIN:ZDB-GENO-980202-1025	Zfish	ZFIN:ZDB-PUB-970210-27\|PMID:9007251
Biological Process	GO:0035162	embryonic hemopoiesis	alas2	IMP	ZFIN:ZDB-GENO-980202-1405	Zfish	ZFIN:ZDB-PUB-970210-27\|PMID:9007251
Biological Process	GO:0035162	embryonic hemopoiesis	alas2	IMP	ZFIN:ZDB-GENO-980202-1025	Zfish	ZFIN:ZDB-PUB-981208-39\|PMID:9806542
Biological Process	GO:0035162	embryonic hemopoiesis	alas2	IMP	ZFIN:ZDB-GENO-980202-1405	Zfish	ZFIN:ZDB-PUB-981208-39\|PMID:9806542
Biological Process	GO:0030218	erythrocyte differentiation	P22557	ISS	UniProtKB:P08680	Human	GO_REF:0000024
Biological Process	GO:0030218	erythrocyte differentiation	Alas2	IMP		Mouse	MGI:MGI:3694153\|PMID:9446639
Biological Process	GO:0030218	erythrocyte differentiation	Alas2	ISS	UniProtKB:P08680	Rat	RGD:1600115
Biological Process	GO:0030218	erythrocyte differentiation	Alas2	ISO	RGD:732282	Rat	RGD:1624291
Biological Process	GO:0006783	heme biosynthetic process	P22557	ISS	UniProtKB:P08680	Human	GO_REF:0000024
Biological Process	GO:0006783	heme biosynthetic process	Alas2	IMP		Mouse	MGI:MGI:3694153\|PMID:9446639
Biological Process	GO:0006783	heme biosynthetic process	Alas2	ISS	UniProtKB:P08680	Rat	RGD:1600115
Biological Process	GO:0006783	heme biosynthetic process	Alas2	ISO	RGD:732282	Rat	RGD:1624291
Biological Process	GO:0006783	heme biosynthetic process	alas2	IMP	ZFIN:ZDB-GENO-980202-1025	Zfish	ZFIN:ZDB-PUB-981208-39\|PMID:9806542
Biological Process	GO:0006783	heme biosynthetic process	alas2	IMP	ZFIN:ZDB-GENO-980202-1405	Zfish	ZFIN:ZDB-PUB-981208-39\|PMID:9806542
Biological Process	GO:0006783	heme biosynthetic process	Alas	ISS	UniProtKB:P13196	Fly	FB:FBrf0159903
Biological Process	GO:0006783	heme biosynthetic process	Alas	ISS	UniProtKB:P22557	Fly	FB:FBrf0159903
Biological Process	GO:0006783	heme biosynthetic process	hemA	ISS	SGD:S000002640	Dicty	dictyBase_REF:10155
Biological Process	GO:0006783	heme biosynthetic process	HEM1	IMP		Yeast	SGD_REF:S000057328\|PMID:7035824
Biological Process	GO:0006783	heme biosynthetic process	hem1	ISS	UniProtKB:P09950	Pombe	PMID:17072883
Biological Process	GO:0042541	hemoglobin biosynthetic process	P22557	ISS	UniProtKB:P08680	Human	GO_REF:0000024
Biological Process	GO:0042541	hemoglobin biosynthetic process	Alas2	IMP		Mouse	MGI:MGI:3694153\|PMID:9446639
Biological Process	GO:0042541	hemoglobin biosynthetic process	Alas2	ISS	UniProtKB:P08680	Rat	RGD:1600115
Biological Process	GO:0042541	hemoglobin biosynthetic process	Alas2	ISO	RGD:732282	Rat	RGD:1624291
Biological Process	GO:0045449	regulation of transcription	HEM1	IMP		Yeast	SGD_REF:S000074341\|PMID:12928433
Biological Process	GO:0001666	response to hypoxia	P22557	IDA		Human	PMID:16234850
Biological Process	GO:0001666	response to hypoxia	Alas2	ISS	UniProtKB:P22557	Rat	RGD:1600115
Biological Process	GO:0001666	response to hypoxia	Alas2	IEP		Rat	RGD:1599040\|PMID:17095594
Biological Process	GO:0001666	response to hypoxia	Alas2	ISO	RGD:736755	Rat	RGD:1624291

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)