Compare GO annotations for ORTHOMCL6424 PPOD cluster

Possible outliers might be spotted in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, zfish, fly, worm, dicty, dicot, yeast, pombe, ecoli.
Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Red arrows indicate "regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Zfish from Zfin; Fly from Flybase; Worm from Wormbase; Dicot from TAIR; Dicty from Dictybase; Yeast from SGD; Pombe from Sanger; Ecoli from EcoliHub.
Organisms with experimental annotations are indicated: EXP, IC, IDA, IEP, IGI, IMP, IPI. In addition, ISS (ISA, ISM, ISO) annotations are so indicated.
Does not include evidence codes: IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Mon Mar 30 18:25:07 2009.

Compare annotations to GO categories for ORTHOMCL6424.

Entry indicates that ortholog exists for this gene.
Colored entries indicate experimental annotation.
Parentheses indicate ISS annotation only.

Category	ID	Term	Human	Mouse	Rat	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli
Molecular Function	GO:0005488	binding	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Molecular Function	GO:0003824	catalytic activity	Human	Mouse	Rat	Chicken	Zfish	(Fly)	X	X	X	X	X	X
Cellular Component	GO:0005623	cell	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Cellular Component	GO:0044464	cell part	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Cellular Component	GO:0005576	extracellular region	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Cellular Component	GO:0044421	extracellular region part	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Cellular Component	GO:0043226	organelle	Human	Mouse	Rat	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0010926	anatomical structure formation	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0065007	biological regulation	(Human)	Mouse	Rat	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0009987	cellular process	(Human)	Mouse	Rat	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0032502	developmental process	(Human)	Mouse	Rat	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0051234	establishment of localization	Human	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0040007	growth	Human	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0002376	immune system process	Human	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0051179	localization	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0040011	locomotion	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0008152	metabolic process	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0032501	multicellular organismal process	(Human)	Mouse	Rat	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0048519	negative regulation of biological process	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0048518	positive regulation of biological process	Human	Mouse	Rat	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0050789	regulation of biological process	(Human)	Mouse	Rat	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0000003	reproduction	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0022414	reproductive process	(Human)	Mouse	(Rat)	Chicken	Zfish	Fly	X	X	X	X	X	X
Biological Process	GO:0050896	response to stimulus	Human	Mouse	Rat	Chicken	Zfish	Fly	X	X	X	X	X	X

Full set of experimental (and ISS) annotations for ORTHOMCL6424

Category	ID	Term	DB Object	Evidence	With_From	Organism	Reference
Molecular Function	GO:0043498	cell surface binding	hh	IDA		Fly	FB:FBrf0189929\|PMID:16630821
Molecular Function	GO:0043498	cell surface binding	hh	IDA		Fly	FB:FBrf0192598\|PMID:17077139
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	hh	ISS		Fly	FB:FBrf0126658
Molecular Function	GO:0043237	laminin-1 binding	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Molecular Function	GO:0043237	laminin-1 binding	Shh	IDA		Mouse	MGI:MGI:3573843\|PMID:15056720
Molecular Function	GO:0043237	laminin-1 binding	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Molecular Function	GO:0043237	laminin-1 binding	Shh	ISO	RGD:736830	Rat	RGD:1624291
Molecular Function	GO:0005113	patched binding	Shh	IPI		Mouse	MGI:MGI:3687672\|PMID:10500113
Molecular Function	GO:0005113	patched binding	Shh	ISO	RGD:736830	Rat	RGD:1624291
Molecular Function	GO:0005515	protein binding	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Molecular Function	GO:0005515	protein binding	Dhh	IPI	UniProtKB:Q9WU59	Mouse	MGI:MGI:1333378\|PMID:10050855
Molecular Function	GO:0005515	protein binding	Shh	IPI	UniProtKB:Q9D1G3	Mouse	MGI:MGI:3772109\|PMID:18081866
Molecular Function	GO:0005515	protein binding	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Molecular Function	GO:0005515	protein binding	Shh	ISO	RGD:736830	Rat	RGD:1624291
Molecular Function	GO:0005515	protein binding	hh	IPI	FB:FBgn0031872	Fly	FB:FBrf0192598\|PMID:17077139
Cellular Component	GO:0009986	cell surface	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Cellular Component	GO:0009986	cell surface	Shh	IDA		Mouse	MGI:MGI:3511726\|PMID:15576403
Cellular Component	GO:0009986	cell surface	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Cellular Component	GO:0009986	cell surface	Shh	ISO	RGD:736830	Rat	RGD:1624291
Cellular Component	GO:0005737	cytoplasm	hh	IDA		Fly	FB:FBrf0055914\|PMID:1280560
Cellular Component	GO:0016023	cytoplasmic membrane-bounded vesicle	hh	IDA		Fly	FB:FBrf0155685\|PMID:12586063
Cellular Component	GO:0030139	endocytic vesicle	hh	IDA		Fly	FB:FBrf0202773\|PMID:18198278
Cellular Component	GO:0005615	extracellular space	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Cellular Component	GO:0005615	extracellular space	Shh	IDA		Mouse	MGI:MGI:2150931\|PMID:7891723
Cellular Component	GO:0005615	extracellular space	Shh	IDA		Mouse	MGI:MGI:1329746\|PMID:10027293
Cellular Component	GO:0005615	extracellular space	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Cellular Component	GO:0005615	extracellular space	Shh	ISO	RGD:736830	Rat	RGD:1624291
Cellular Component	GO:0045121	membrane raft	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Cellular Component	GO:0045121	membrane raft	Shh	IDA		Mouse	MGI:MGI:3039193\|PMID:15075292
Cellular Component	GO:0045121	membrane raft	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Cellular Component	GO:0045121	membrane raft	Shh	ISO	RGD:736830	Rat	RGD:1624291
Cellular Component	GO:0005634	nucleus	hh	IDA		Fly	FB:FBrf0055914\|PMID:1280560
Biological Process	GO:0021984	adenohypophysis development	shha	IDA		Zfish	ZFIN:ZDB-PUB-030304-4\|PMID:12606279
Biological Process	GO:0021984	adenohypophysis development	shha	IMP	ZFIN:ZDB-GENO-010427-4	Zfish	ZFIN:ZDB-PUB-030304-4\|PMID:12606279
Biological Process	GO:0048856	anatomical structure development	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:2148409\|PMID:11485934
Biological Process	GO:0048856	anatomical structure development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	Shh	IMP	MGI:MGI:1934261	Mouse	MGI:MGI:1289788\|PMID:9768363
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0008209	androgen metabolic process	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0008209	androgen metabolic process	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3037217\|PMID:15013801
Biological Process	GO:0008209	androgen metabolic process	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0008209	androgen metabolic process	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0001525	angiogenesis	Shh	IDA		Mouse	MGI:MGI:3629544\|PMID:16778080
Biological Process	GO:0001525	angiogenesis	Shh	IGI	MGI:MGI:95516	Mouse	MGI:MGI:3701403\|PMID:17187775
Biological Process	GO:0001525	angiogenesis	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3701403\|PMID:17187775
Biological Process	GO:0001525	angiogenesis	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0021960	anterior commissure morphogenesis	hh	IMP		Fly	FB:FBrf0190277\|PMID:16467357
Biological Process	GO:0009952	anterior/posterior pattern formation	Shh	IMP	MGI:MGI:2387802	Mouse	MGI:MGI:2135419\|PMID:11389830
Biological Process	GO:0009952	anterior/posterior pattern formation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0009952	anterior/posterior pattern formation	Q91035	IDA		Chicken	PMID:8269518
Biological Process	GO:0009952	anterior/posterior pattern formation	shha	IGI	ZFIN:ZDB-GENO-010426-2\|ZFIN:ZDB-GENO-980202-1194	Zfish	ZFIN:ZDB-PUB-030304-16\|PMID:12588855
Biological Process	GO:0007411	axon guidance	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0007411	axon guidance	Shh	IDA		Mouse	MGI:MGI:2654974\|PMID:12679031
Biological Process	GO:0007411	axon guidance	Shh	IMP	MGI:MGI:1934268	Mouse	MGI:MGI:2662556\|PMID:12756179
Biological Process	GO:0007411	axon guidance	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0007411	axon guidance	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0060020	Bergmann glial cell differentiation	Shh	IDA		Mouse	MGI:MGI:1338342\|PMID:10375501
Biological Process	GO:0060020	Bergmann glial cell differentiation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0008015	blood circulation	shha	IMP	ZFIN:ZDB-GENO-980410-268	Zfish	ZFIN:ZDB-PUB-970210-25\|PMID:9007249
Biological Process	GO:0007596	blood coagulation	Shh	IMP	MGI:MGI:1860897	Mouse	MGI:MGI:79294\|PMID:8835524
Biological Process	GO:0007596	blood coagulation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0001746	Bolwig's organ morphogenesis	hh	IMP		Fly	FB:FBrf0126773\|PMID:10704398
Biological Process	GO:0007420	brain development	shha	IMP	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-030707-3\|PMID:12843251
Biological Process	GO:0048754	branching morphogenesis of a tube	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3039063\|PMID:15042696
Biological Process	GO:0048754	branching morphogenesis of a tube	Shh	IMP	MGI:MGI:1934268\|MGI:MGI:2679524	Mouse	MGI:MGI:3050270\|PMID:15305287
Biological Process	GO:0048754	branching morphogenesis of a tube	Shh	IMP	MGI:MGI:1934261	Mouse	MGI:MGI:1289788\|PMID:9768363
Biological Process	GO:0048754	branching morphogenesis of a tube	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0043010	camera-type eye development	Shh	IDA		Mouse	MGI:MGI:2385969\|PMID:12195432
Biological Process	GO:0043010	camera-type eye development	Shh	IMP	MGI:MGI:1934268	Mouse	MGI:MGI:2662556\|PMID:12756179
Biological Process	GO:0043010	camera-type eye development	Shh	IMP	MGI:MGI:1934268\|MGI:MGI:3052661	Mouse	MGI:MGI:3608482\|PMID:16236765
Biological Process	GO:0043010	camera-type eye development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0043010	camera-type eye development	shha	IDA		Zfish	ZFIN:ZDB-PUB-050426-1\|PMID:15728669
Biological Process	GO:0035143	caudal fin morphogenesis	shha	IMP	ZFIN:ZDB-GENO-080418-2	Zfish	ZFIN:ZDB-PUB-070711-11\|PMID:17597528
Biological Process	GO:0022402	cell cycle process	Dhh	IGI	MGI:MGI:1095403	Mouse	MGI:MGI:3769860\|PMID:17495005
Biological Process	GO:0048468	cell development	Shh	IMP	MGI:MGI:1934268\|MGI:MGI:2387802	Mouse	MGI:MGI:3051930\|PMID:15183722
Biological Process	GO:0048468	cell development	Shh	IMP	MGI:MGI:1934268\|MGI:MGI:3052661	Mouse	MGI:MGI:3608482\|PMID:16236765
Biological Process	GO:0048468	cell development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0045165	cell fate commitment	Shh	IGI	MGI:MGI:95655	Mouse	MGI:MGI:3710451\|PMID:17504941
Biological Process	GO:0045165	cell fate commitment	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0001708	cell fate specification	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0001708	cell fate specification	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:2387225\|PMID:12231626
Biological Process	GO:0001708	cell fate specification	Shh	IGI	MGI:MGI:1926387	Mouse	MGI:MGI:3624618\|PMID:16647304
Biological Process	GO:0001708	cell fate specification	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0001708	cell fate specification	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0001708	cell fate specification	shha	IMP		Zfish	ZFIN:ZDB-PUB-040706-2\|PMID:15229178
Biological Process	GO:0007267	cell-cell signaling	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0007267	cell-cell signaling	Shh	IMP	MGI:MGI:1934268	Mouse	MGI:MGI:3045497\|PMID:15199404
Biological Process	GO:0007267	cell-cell signaling	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3617552\|PMID:16492970
Biological Process	GO:0007267	cell-cell signaling	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0007267	cell-cell signaling	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0007417	central nervous system development	Shh	IMP		Mouse	MGI:MGI:2445271\|PMID:12435628
Biological Process	GO:0007417	central nervous system development	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0007417	central nervous system development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0007417	central nervous system development	shha	IMP	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-030919-9\|PMID:13129844
Biological Process	GO:0035231	cytoneme assembly	hh	IMP		Fly	FB:FBrf0109017\|PMID:10367889
Biological Process	GO:0007368	determination of left/right symmetry	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:1339521\|PMID:10385121
Biological Process	GO:0007368	determination of left/right symmetry	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:1340887\|PMID:10411502
Biological Process	GO:0048589	developmental growth	Shh	IMP	MGI:MGI:1934268\|MGI:MGI:2445832	Mouse	MGI:MGI:1926240\|PMID:11044393
Biological Process	GO:0048589	developmental growth	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0021536	diencephalon development	shha	IGI	ZFIN:ZDB-GENO-070406-1\|ZFIN:ZDB-MRPHLNO-070522-3	Zfish	ZFIN:ZDB-PUB-080327-9\|PMID:18358464
Biological Process	GO:0048546	digestive tract morphogenesis	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:1277744\|PMID:9731532
Biological Process	GO:0048546	digestive tract morphogenesis	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Shh	IGI	MGI:MGI:95655	Mouse	MGI:MGI:3710451\|PMID:17504941
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Shh	IDA		Mouse	MGI:MGI:3710017\|PMID:17442700
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Shh	IDA		Mouse	MGI:MGI:3806189\|PMID:18590716
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0009953	dorsal/ventral pattern formation	Shh	IGI	MGI:MGI:1916147	Mouse	MGI:MGI:3051703\|PMID:15269168
Biological Process	GO:0009953	dorsal/ventral pattern formation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0009953	dorsal/ventral pattern formation	shha	IMP	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-041115-5\|PMID:15539490
Biological Process	GO:0031076	embryonic camera-type eye development	shha	IMP	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-050506-5\|PMID:15857917
Biological Process	GO:0009790	embryonic development	Shh	IGI	MGI:MGI:104719	Mouse	MGI:MGI:3588476\|PMID:16020517
Biological Process	GO:0009790	embryonic development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0042733	embryonic digit morphogenesis	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0042733	embryonic digit morphogenesis	Shh	IGI	MGI:MGI:98715	Mouse	MGI:MGI:3579954\|PMID:15930098
Biological Process	GO:0042733	embryonic digit morphogenesis	Shh	IGI	MGI:MGI:95655	Mouse	MGI:MGI:3710451\|PMID:17504941
Biological Process	GO:0042733	embryonic digit morphogenesis	Shh	IGI	MGI:MGI:95655	Mouse	MGI:MGI:3710452\|PMID:17504940
Biological Process	GO:0042733	embryonic digit morphogenesis	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0042733	embryonic digit morphogenesis	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0042733	embryonic digit morphogenesis	Q91035	IMP		Chicken	PMID:11044396
Biological Process	GO:0030326	embryonic limb morphogenesis	Shh	IMP	MGI:MGI:3053959\|MGI:MGI:3053960	Mouse	MGI:MGI:3053241\|PMID:15315763
Biological Process	GO:0030326	embryonic limb morphogenesis	Shh	IMP	MGI:MGI:2387802	Mouse	MGI:MGI:2135419\|PMID:11389830
Biological Process	GO:0030326	embryonic limb morphogenesis	Shh	IGI	MGI:MGI:105373	Mouse	MGI:MGI:2135419\|PMID:11389830
Biological Process	GO:0030326	embryonic limb morphogenesis	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0048598	embryonic morphogenesis	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3617552\|PMID:16492970
Biological Process	GO:0048598	embryonic morphogenesis	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	shha	IMP	ZFIN:ZDB-GENO-980410-268	Zfish	ZFIN:ZDB-PUB-050803-5\|PMID:16049113
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	shha	IGI	ZFIN:ZDB-MRPHLNO-041129-2\|ZFIN:ZDB-MRPHLNO-050204-6	Zfish	ZFIN:ZDB-PUB-050803-5\|PMID:16049113
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	shhb	IGI	ZFIN:ZDB-MRPHLNO-041129-2\|ZFIN:ZDB-MRPHLNO-050204-6	Zfish	ZFIN:ZDB-PUB-050803-5\|PMID:16049113
Biological Process	GO:0048568	embryonic organ development	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3612368\|PMID:15680353
Biological Process	GO:0048568	embryonic organ development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0048706	embryonic skeletal system development	Shh	IGI	MGI:MGI:95655	Mouse	MGI:MGI:3710451\|PMID:17504941
Biological Process	GO:0048706	embryonic skeletal system development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	shha	IMP	ZFIN:ZDB-GENO-010427-4	Zfish	ZFIN:ZDB-PUB-060412-2\|PMID:16580747
Biological Process	GO:0031018	endocrine pancreas development	shha	IDA		Zfish	ZFIN:ZDB-PUB-020402-4\|PMID:11900460
Biological Process	GO:0031018	endocrine pancreas development	shha	IMP	ZFIN:ZDB-GENO-070406-1	Zfish	ZFIN:ZDB-PUB-020402-4\|PMID:11900460
Biological Process	GO:0007427	epithelial cell migration, open tracheal system	hh	IMP		Fly	FB:FBrf0135726\|PMID:11290298
Biological Process	GO:0048592	eye morphogenesis	hh	IMP		Fly	FB:FBrf0193969\|PMID:16651542
Biological Process	GO:0042462	eye photoreceptor cell development	shha	IMP	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-040719-3\|PMID:15253932
Biological Process	GO:0042462	eye photoreceptor cell development	shha	IMP	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-050518-13\|PMID:15891769
Biological Process	GO:0033504	floor plate development	shha	IMP	ZFIN:ZDB-GENO-070406-1	Zfish	ZFIN:ZDB-PUB-000309-33\|PMID:10694427
Biological Process	GO:0033504	floor plate development	shha	IMP	ZFIN:ZDB-GENO-070215-11	Zfish	ZFIN:ZDB-PUB-000309-33\|PMID:10694427
Biological Process	GO:0033504	floor plate development	shha	IMP	ZFIN:ZDB-GENO-980410-268	Zfish	ZFIN:ZDB-PUB-000309-33\|PMID:10694427
Biological Process	GO:0021508	floor plate formation	shha	IMP	ZFIN:ZDB-GENO-070406-1	Zfish	ZFIN:ZDB-PUB-000309-33\|PMID:10694427
Biological Process	GO:0021508	floor plate formation	shha	IGI	ZFIN:ZDB-GENO-070712-5	Zfish	ZFIN:ZDB-PUB-030115-17\|PMID:12508225
Biological Process	GO:0030900	forebrain development	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0030900	forebrain development	Shh	IGI	MGI:MGI:104719	Mouse	MGI:MGI:3588476\|PMID:16020517
Biological Process	GO:0030900	forebrain development	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0030900	forebrain development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0030900	forebrain development	shha	IMP	ZFIN:ZDB-GENO-010427-4	Zfish	ZFIN:ZDB-PUB-060207-11\|PMID:16452095
Biological Process	GO:0030900	forebrain development	shhb	IMP	ZFIN:ZDB-MRPHLNO-060508-2	Zfish	ZFIN:ZDB-PUB-060207-11\|PMID:16452095
Biological Process	GO:0048859	formation of anatomical boundary	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:1277744\|PMID:9731532
Biological Process	GO:0048859	formation of anatomical boundary	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0035224	genital disc anterior/posterior pattern formation	hh	IEP		Fly	FB:FBrf0088118\|PMID:8798147
Biological Process	GO:0035215	genital disc development	hh	IMP		Fly	FB:FBrf0187379\|PMID:15893978
Biological Process	GO:0008354	germ cell migration	hh	IMP		Fly	FB:FBrf0100771\|PMID:9435287
Biological Process	GO:0010001	glial cell differentiation	shha	IMP	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-040719-3\|PMID:15253932
Biological Process	GO:0008347	glial cell migration	hh	IMP		Fly	FB:FBrf0145174\|PMID:11804568
Biological Process	GO:0042063	gliogenesis	shhb	IGI	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-041115-5\|PMID:15539490
Biological Process	GO:0042063	gliogenesis	shha	IGI	ZFIN:ZDB-GENE-980526-41	Zfish	ZFIN:ZDB-PUB-041115-5\|PMID:15539490
Biological Process	GO:0042063	gliogenesis	shha	IMP	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-041115-5\|PMID:15539490
Biological Process	GO:0032835	glomerulus development	shha	IMP	ZFIN:ZDB-GENO-070917-2	Zfish	ZFIN:ZDB-PUB-000824-1\|PMID:10885753
Biological Process	GO:0007506	gonadal mesoderm development	hh	IMP		Fly	FB:FBrf0100771\|PMID:9435287
Biological Process	GO:0001942	hair follicle development	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3589306\|PMID:16054035
Biological Process	GO:0001942	hair follicle development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0031069	hair follicle morphogenesis	Shh	IMP	MGI:MGI:1934261	Mouse	MGI:MGI:1289785\|PMID:9768360
Biological Process	GO:0031069	hair follicle morphogenesis	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0007507	heart development	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0007507	heart development	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3664714\|PMID:11172440
Biological Process	GO:0007507	heart development	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3583396\|PMID:15936751
Biological Process	GO:0007507	heart development	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0007507	heart development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0001947	heart looping	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:1340887\|PMID:10411502
Biological Process	GO:0001947	heart looping	shha	IDA		Zfish	ZFIN:ZDB-PUB-971203-9\|PMID:9334285
Biological Process	GO:0030902	hindbrain development	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0030902	hindbrain development	Shh	IMP	MGI:MGI:1934268\|MGI:MGI:2387802	Mouse	MGI:MGI:3051930\|PMID:15183722
Biological Process	GO:0030902	hindbrain development	Shh	IGI	MGI:MGI:95728	Mouse	MGI:MGI:3512837\|PMID:15496441
Biological Process	GO:0030902	hindbrain development	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0030902	hindbrain development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0030902	hindbrain development	shha	IMP	ZFIN:ZDB-GENO-010427-4	Zfish	ZFIN:ZDB-PUB-040804-3\|PMID:15281067
Biological Process	GO:0007442	hindgut morphogenesis	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:2148409\|PMID:11485934
Biological Process	GO:0007442	hindgut morphogenesis	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0007442	hindgut morphogenesis	hh	IMP		Fly	FB:FBrf0134749\|PMID:11231061
Biological Process	GO:0008624	induction of apoptosis by extracellular signals	Q91035	IDA		Chicken	PMID:11044396
Biological Process	GO:0048839	inner ear development	shha	IGI	ZFIN:ZDB-GENO-010426-2\|ZFIN:ZDB-GENO-980202-1194	Zfish	ZFIN:ZDB-PUB-030304-16\|PMID:12588855
Biological Process	GO:0001822	kidney development	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3664714\|PMID:11172440
Biological Process	GO:0001822	kidney development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0035217	labial disc development	hh	IMP		Fly	FB:FBrf0183854\|PMID:15680366
Biological Process	GO:0033327	Leydig cell differentiation	Dhh	IMP	MGI:MGI:1934259	Mouse	MGI:MGI:2450504\|PMID:12050120
Biological Process	GO:0033327	Leydig cell differentiation	Dhh	IGI	MGI:MGI:1095403	Mouse	MGI:MGI:3769860\|PMID:17495005
Biological Process	GO:0030324	lung development	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0030324	lung development	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3701403\|PMID:17187775
Biological Process	GO:0030324	lung development	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:1277744\|PMID:9731532
Biological Process	GO:0030324	lung development	Shh	IMP	MGI:MGI:1934268\|MGI:MGI:2679524	Mouse	MGI:MGI:3050270\|PMID:15305287
Biological Process	GO:0030324	lung development	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3051935\|PMID:15136151
Biological Process	GO:0030324	lung development	Shh	IGI	MGI:MGI:95729	Mouse	MGI:MGI:3051935\|PMID:15136151
Biological Process	GO:0030324	lung development	Shh	IMP	MGI:MGI:1934261	Mouse	MGI:MGI:1289788\|PMID:9768363
Biological Process	GO:0030324	lung development	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0030324	lung development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0030539	male genitalia development	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0030539	male genitalia development	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:2152294\|PMID:11684660
Biological Process	GO:0030539	male genitalia development	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0030539	male genitalia development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0030238	male sex determination	Dhh	IGI	MGI:MGI:1095403	Mouse	MGI:MGI:3769860\|PMID:17495005
Biological Process	GO:0001656	metanephros development	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0001656	metanephros development	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3611729\|PMID:16396903
Biological Process	GO:0001656	metanephros development	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0001656	metanephros development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0030901	midbrain development	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0030901	midbrain development	Shh	IGI	MGI:MGI:104719	Mouse	MGI:MGI:3588476\|PMID:16020517
Biological Process	GO:0030901	midbrain development	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0030901	midbrain development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0016335	morphogenesis of larval imaginal disc epithelium	hh	IMP		Fly	FB:FBrf0190309\|PMID:16236766
Biological Process	GO:0007517	muscle development	shha	IMP	ZFIN:ZDB-GENO-070228-3	Zfish	ZFIN:ZDB-PUB-061020-53\|PMID:17046741
Biological Process	GO:0045445	myoblast differentiation	Shh	IDA		Mouse	MGI:MGI:3621570\|PMID:15238161
Biological Process	GO:0045445	myoblast differentiation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0046639	negative regulation of alpha-beta T cell differentiation	Shh	IMP		Mouse	MGI:MGI:1888832\|PMID:10981962
Biological Process	GO:0046639	negative regulation of alpha-beta T cell differentiation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0043066	negative regulation of apoptosis	Q91035	IDA		Chicken	PMID:11044396
Biological Process	GO:0045596	negative regulation of cell differentiation	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0045596	negative regulation of cell differentiation	Shh	IDA		Mouse	MGI:MGI:3053236\|PMID:15337776
Biological Process	GO:0045596	negative regulation of cell differentiation	Shh	IMP	MGI:MGI:1934268\|MGI:MGI:3052661	Mouse	MGI:MGI:3608482\|PMID:16236765
Biological Process	GO:0045596	negative regulation of cell differentiation	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0045596	negative regulation of cell differentiation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0030336	negative regulation of cell migration	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0030336	negative regulation of cell migration	Shh	IDA		Mouse	MGI:MGI:3053236\|PMID:15337776
Biological Process	GO:0030336	negative regulation of cell migration	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0030336	negative regulation of cell migration	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0008285	negative regulation of cell proliferation	shha	IMP	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-050518-13\|PMID:15891769
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Shh	IMP		Mouse	MGI:MGI:3624046\|PMID:16611981
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0042177	negative regulation of protein catabolic process	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3624046\|PMID:16611981
Biological Process	GO:0042177	negative regulation of protein catabolic process	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0042130	negative regulation of T cell proliferation	Shh	IMP		Mouse	MGI:MGI:1888832\|PMID:10981962
Biological Process	GO:0042130	negative regulation of T cell proliferation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0007399	nervous system development	shha	IMP	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-030919-9\|PMID:13129844
Biological Process	GO:0001755	neural crest cell migration	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0001755	neural crest cell migration	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3583396\|PMID:15936751
Biological Process	GO:0001755	neural crest cell migration	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0001755	neural crest cell migration	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0001839	neural plate morphogenesis	shha	IMP		Zfish	ZFIN:ZDB-PUB-060313-5\|PMID:16502420
Biological Process	GO:0001841	neural tube formation	Shh	IMP		Rat	RGD:69996\|PMID:8124714
Biological Process	GO:0007405	neuroblast proliferation	Shh	IDA		Mouse	MGI:MGI:3053236\|PMID:15337776
Biological Process	GO:0007405	neuroblast proliferation	Shh	IEP		Rat	RGD:729868\|PMID:12469128
Biological Process	GO:0007405	neuroblast proliferation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0030182	neuron differentiation	shha	IMP	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-030707-3\|PMID:12843251
Biological Process	GO:0030182	neuron differentiation	shha	IMP		Zfish	ZFIN:ZDB-PUB-060313-5\|PMID:16502420
Biological Process	GO:0030182	neuron differentiation	shhb	IMP		Zfish	ZFIN:ZDB-PUB-060313-5\|PMID:16502420
Biological Process	GO:0048663	neuron fate commitment	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0048663	neuron fate commitment	Shh	IMP	MGI:MGI:1934268	Mouse	MGI:MGI:3608263\|PMID:16221724
Biological Process	GO:0048663	neuron fate commitment	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0048663	neuron fate commitment	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0048663	neuron fate commitment	shha	IGI	ZFIN:ZDB-GENE-980526-41	Zfish	ZFIN:ZDB-PUB-041115-5\|PMID:15539490
Biological Process	GO:0048663	neuron fate commitment	shhb	IGI	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-041115-5\|PMID:15539490
Biological Process	GO:0042475	odontogenesis of dentine-containing tooth	Shh	IMP	MGI:MGI:1934268\|MGI:MGI:2445832	Mouse	MGI:MGI:1926240\|PMID:11044393
Biological Process	GO:0042475	odontogenesis of dentine-containing tooth	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0014003	oligodendrocyte development	Shh	IDA		Mouse	MGI:MGI:81674\|PMID:8660874
Biological Process	GO:0014003	oligodendrocyte development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0007424	open tracheal system development	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:1277744\|PMID:9731532
Biological Process	GO:0007424	open tracheal system development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0009887	organ morphogenesis	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:2681050\|PMID:14623238
Biological Process	GO:0009887	organ morphogenesis	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0009887	organ morphogenesis	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0002076	osteoblast development	Shh	IDA		Mouse	MGI:MGI:3653954\|PMID:16880529
Biological Process	GO:0002076	osteoblast development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0031016	pancreas development	shha	IEP		Zfish	ZFIN:ZDB-PUB-070212-42\|PMID:17289013
Biological Process	GO:0031016	pancreas development	shha	IDA		Zfish	ZFIN:ZDB-PUB-010905-3\|PMID:11553330
Biological Process	GO:0031016	pancreas development	shha	IMP	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-010905-3\|PMID:11553330
Biological Process	GO:0007389	pattern specification process	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0007389	pattern specification process	Shh	IGI	MGI:MGI:95729	Mouse	MGI:MGI:2683891\|PMID:14602680
Biological Process	GO:0007389	pattern specification process	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:2387225\|PMID:12231626
Biological Process	GO:0007389	pattern specification process	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0007389	pattern specification process	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0001569	patterning of blood vessels	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0001569	patterning of blood vessels	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3583396\|PMID:15936751
Biological Process	GO:0001569	patterning of blood vessels	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0001569	patterning of blood vessels	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0033339	pectoral fin development	shha	IMP	ZFIN:ZDB-GENO-980410-268	Zfish	ZFIN:ZDB-PUB-980729-15\|PMID:9655820
Biological Process	GO:0033339	pectoral fin development	shha	IMP	ZFIN:ZDB-GENO-080729-2	Zfish	ZFIN:ZDB-PUB-980729-15\|PMID:9655820
Biological Process	GO:0033339	pectoral fin development	shha	IMP		Zfish	ZFIN:ZDB-PUB-970210-21\|PMID:9007245
Biological Process	GO:0009949	polarity specification of anterior/posterior axis	Q91035	IMP		Chicken	PMID:11044396
Biological Process	GO:0007280	pole cell migration	hh	IGI	FB:FBgn0001205	Fly	FB:FBrf0190201\|PMID:16256738
Biological Process	GO:0007280	pole cell migration	hh	IGI	FB:FBgn0029088	Fly	FB:FBrf0190201\|PMID:16256738
Biological Process	GO:0008284	positive regulation of cell proliferation	Shh	IDA		Mouse	MGI:MGI:2154469\|PMID:11748155
Biological Process	GO:0008284	positive regulation of cell proliferation	Shh	IMP	MGI:MGI:1934268\|MGI:MGI:2387802	Mouse	MGI:MGI:3051930\|PMID:15183722
Biological Process	GO:0008284	positive regulation of cell proliferation	Shh	IGI	MGI:MGI:95728	Mouse	MGI:MGI:3512837\|PMID:15496441
Biological Process	GO:0008284	positive regulation of cell proliferation	Shh	IMP	MGI:MGI:1934268\|MGI:MGI:3052661	Mouse	MGI:MGI:3608482\|PMID:16236765
Biological Process	GO:0008284	positive regulation of cell proliferation	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3611729\|PMID:16396903
Biological Process	GO:0008284	positive regulation of cell proliferation	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3589306\|PMID:16054035
Biological Process	GO:0008284	positive regulation of cell proliferation	Shh	IGI	MGI:MGI:95728	Mouse	MGI:MGI:3589306\|PMID:16054035
Biological Process	GO:0008284	positive regulation of cell proliferation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0021940	positive regulation of granule cell precursor proliferation	Shh	IDA		Mouse	MGI:MGI:1329746\|PMID:10027293
Biological Process	GO:0021940	positive regulation of granule cell precursor proliferation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0007228	positive regulation of hh target transcription factor activity	Shh	IDA		Mouse	MGI:MGI:3624046\|PMID:16611981
Biological Process	GO:0007228	positive regulation of hh target transcription factor activity	Shh	IGI	MGI:MGI:95728	Mouse	MGI:MGI:3653954\|PMID:16880529
Biological Process	GO:0007228	positive regulation of hh target transcription factor activity	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0007228	positive regulation of hh target transcription factor activity	hh	IGI	FB:FBgn0005355	Fly	FB:FBrf0105900\|PMID:9874371
Biological Process	GO:0007228	positive regulation of hh target transcription factor activity	hh	IGI	FB:FBgn0001079	Fly	FB:FBrf0105900\|PMID:9874371
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:1277744\|PMID:9731532
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Shh	IDA		Mouse	MGI:MGI:2154469\|PMID:11748155
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0045666	positive regulation of neuron differentiation	Shh	IMP		Rat	RGD:69996\|PMID:8124714
Biological Process	GO:0042307	positive regulation of protein import into nucleus	Shh	IGI	MGI:MGI:108075	Mouse	MGI:MGI:3686547\|PMID:17043310
Biological Process	GO:0042307	positive regulation of protein import into nucleus	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Shh	IGI	MGI:MGI:95728	Mouse	MGI:MGI:3653954\|PMID:16880529
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0048618	post-embryonic foregut morphogenesis	shha	IMP	ZFIN:ZDB-GENO-010427-4	Zfish	ZFIN:ZDB-PUB-030312-8\|PMID:12618131
Biological Process	GO:0007458	progression of morphogenetic furrow during compound eye morphogenesis	hh	IEP		Fly	FB:FBrf0064592\|PMID:8252628
Biological Process	GO:0007458	progression of morphogenetic furrow during compound eye morphogenesis	hh	IGI	FB:FBgn0000490	Fly	FB:FBrf0064592\|PMID:8252628
Biological Process	GO:0007458	progression of morphogenetic furrow during compound eye morphogenesis	hh	IGI	FB:FBgn0001168	Fly	FB:FBrf0064592\|PMID:8252628
Biological Process	GO:0007458	progression of morphogenetic furrow during compound eye morphogenesis	hh	IGI	FB:FBgn0003326	Fly	FB:FBrf0064592\|PMID:8252628
Biological Process	GO:0007458	progression of morphogenetic furrow during compound eye morphogenesis	hh	IMP		Fly	FB:FBrf0064592\|PMID:8252628
Biological Process	GO:0030850	prostate gland development	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0030850	prostate gland development	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3037217\|PMID:15013801
Biological Process	GO:0030850	prostate gland development	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0030850	prostate gland development	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0016540	protein autoprocessing	hh	IDA		Fly	FB:FBrf0099245\|PMID:9335337
Biological Process	GO:0016540	protein autoprocessing	hh	IMP		Fly	FB:FBrf0099245\|PMID:9335337
Biological Process	GO:0042127	regulation of cell proliferation	Shh	IDA		Mouse	MGI:MGI:2662556\|PMID:12756179
Biological Process	GO:0042127	regulation of cell proliferation	Shh	IDA		Rat	RGD:628387\|PMID:12417650
Biological Process	GO:0042127	regulation of cell proliferation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0030856	regulation of epithelial cell differentiation	Shh	IEP		Rat	RGD:1580346\|PMID:14651923
Biological Process	GO:0010468	regulation of gene expression	Shh	ISO	UniProtKB:Q92008	Mouse	MGI:MGI:1329807\|PMID:10021344
Biological Process	GO:0010468	regulation of gene expression	Shh	IMP		Mouse	MGI:MGI:3822094\|PMID:18799682
Biological Process	GO:0010468	regulation of gene expression	Shh	IGI	MGI:MGI:95729	Mouse	MGI:MGI:3822094\|PMID:18799682
Biological Process	GO:0010468	regulation of gene expression	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0007346	regulation of mitotic cell cycle	hh	IMP		Fly	FB:FBrf0135358\|PMID:11279500
Biological Process	GO:0042306	regulation of protein import into nucleus	hh	IMP		Fly	FB:FBrf0167511\|PMID:14597576
Biological Process	GO:0030162	regulation of proteolysis	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0030162	regulation of proteolysis	Shh	IDA		Mouse	MGI:MGI:3051935\|PMID:15136151
Biological Process	GO:0030162	regulation of proteolysis	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0030162	regulation of proteolysis	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0050810	regulation of steroid biosynthetic process	Dhh	IGI	MGI:MGI:1095403	Mouse	MGI:MGI:3769860\|PMID:17495005
Biological Process	GO:0045449	regulation of transcription	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:2136712\|PMID:11412027
Biological Process	GO:0045449	regulation of transcription	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	shha	IMP	ZFIN:ZDB-GENO-010426-2	Zfish	ZFIN:ZDB-PUB-020820-6\|PMID:12110173
Biological Process	GO:0048678	response to axon injury	Shh	IMP		Rat	RGD:1580344\|PMID:15356205
Biological Process	GO:0032526	response to retinoic acid	Q91035	IDA		Chicken	PMID:8269518
Biological Process	GO:0007435	salivary gland morphogenesis	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0007435	salivary gland morphogenesis	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3039063\|PMID:15042696
Biological Process	GO:0007435	salivary gland morphogenesis	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0007435	salivary gland morphogenesis	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0007367	segment polarity determination	hh	IEP		Fly	FB:FBrf0055914\|PMID:1280560
Biological Process	GO:0007367	segment polarity determination	hh	IMP		Fly	FB:FBrf0187474\|PMID:15930099
Biological Process	GO:0007165	signal transduction	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0007165	signal transduction	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0048741	skeletal muscle fiber development	shha	IGI	ZFIN:ZDB-MRPHLNO-071210-2\|ZFIN:ZDB-MRPHLNO-071210-3	Zfish	ZFIN:ZDB-PUB-070820-13\|PMID:17699609
Biological Process	GO:0048741	skeletal muscle fiber development	shha	IGI	ZFIN:ZDB-MRPHLNO-070529-1\|ZFIN:ZDB-MRPHLNO-070529-2\|ZFIN:ZDB-MRPHLNO-070529-3\|ZFIN:ZDB-MRPHLNO-070529-4	Zfish	ZFIN:ZDB-PUB-070820-13\|PMID:17699609
Biological Process	GO:0048741	skeletal muscle fiber development	shha	IDA		Zfish	ZFIN:ZDB-PUB-070820-13\|PMID:17699609
Biological Process	GO:0007224	smoothened signaling pathway	Shh	IDA		Mouse	MGI:MGI:84001\|PMID:8906787
Biological Process	GO:0007224	smoothened signaling pathway	Shh	IGI	MGI:MGI:1916147	Mouse	MGI:MGI:3051703\|PMID:15269168
Biological Process	GO:0007224	smoothened signaling pathway	Shh	IGI	MGI:MGI:108075	Mouse	MGI:MGI:3686547\|PMID:17043310
Biological Process	GO:0007224	smoothened signaling pathway	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0007224	smoothened signaling pathway	shha	IGI	ZFIN:ZDB-GENO-010426-2\|ZFIN:ZDB-GENO-980202-1517	Zfish	ZFIN:ZDB-PUB-060424-5\|PMID:16626681
Biological Process	GO:0007224	smoothened signaling pathway	hh	IGI	FB:FBgn0003444	Fly	FB:FBrf0089881\|PMID:8700230
Biological Process	GO:0021938	smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation	Shh	IMP		Mouse	MGI:MGI:1338342\|PMID:10375501
Biological Process	GO:0021938	smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation	Shh	IDA		Mouse	MGI:MGI:1338342\|PMID:10375501
Biological Process	GO:0021938	smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0001756	somitogenesis	shha	IMP	ZFIN:ZDB-GENO-980410-268	Zfish	ZFIN:ZDB-PUB-980729-15\|PMID:9655820
Biological Process	GO:0001756	somitogenesis	shha	IMP	ZFIN:ZDB-GENO-080729-2	Zfish	ZFIN:ZDB-PUB-980729-15\|PMID:9655820
Biological Process	GO:0001756	somitogenesis	shha	IGI	ZFIN:ZDB-GENO-070406-1\|ZFIN:ZDB-MRPHLNO-080924-3	Zfish	ZFIN:ZDB-PUB-080311-8\|PMID:18326814
Biological Process	GO:0007286	spermatid development	Dhh	IMP	MGI:MGI:1934259	Mouse	MGI:MGI:3769860\|PMID:17495005
Biological Process	GO:0021513	spinal cord dorsal/ventral patterning	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:2154468\|PMID:11748151
Biological Process	GO:0021513	spinal cord dorsal/ventral patterning	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0035277	spiracle morphogenesis, open tracheal system	hh	IMP		Fly	FB:FBrf0187474\|PMID:15930099
Biological Process	GO:0055002	striated muscle cell development	shhb	IGI	ZFIN:ZDB-GENO-980202-1526	Zfish	ZFIN:ZDB-PUB-010416-5\|PMID:11428131
Biological Process	GO:0055002	striated muscle cell development	shha	IMP	ZFIN:ZDB-GENO-070406-1	Zfish	ZFIN:ZDB-PUB-010416-5\|PMID:11428131
Biological Process	GO:0051146	striated muscle cell differentiation	Shh	IDA		Mouse	MGI:MGI:3621570\|PMID:15238161
Biological Process	GO:0051146	striated muscle cell differentiation	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3621570\|PMID:15238161
Biological Process	GO:0051146	striated muscle cell differentiation	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0021978	telencephalon regionalization	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:1926244\|PMID:11060228
Biological Process	GO:0021978	telencephalon regionalization	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0043587	tongue morphogenesis	Shh	IMP		Rat	RGD:1580345\|PMID:15581865
Biological Process	GO:0001658	ureteric bud branching	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0001658	ureteric bud branching	Shh	IMP	MGI:MGI:1857796	Mouse	MGI:MGI:3611729\|PMID:16396903
Biological Process	GO:0001658	ureteric bud branching	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0001658	ureteric bud branching	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0001570	vasculogenesis	Q15465	ISS	UniProtKB:Q62226	Human	GO_REF:0000024
Biological Process	GO:0001570	vasculogenesis	Shh	IDA		Mouse	MGI:MGI:3051693\|PMID:15294868
Biological Process	GO:0001570	vasculogenesis	Shh	ISS	UniProtKB:Q62226	Rat	RGD:1600115
Biological Process	GO:0001570	vasculogenesis	Shh	ISO	RGD:736830	Rat	RGD:1624291
Biological Process	GO:0007418	ventral midline development	hh	IMP		Fly	FB:FBrf0190277\|PMID:16467357

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)