Compare GO annotations for ORTHOMCL13110 PPOD cluster

Possible outliers might be spotted in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, zfish, fly, worm, dicty, dicot, yeast, pombe, ecoli.
Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Red arrows indicate "regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Zfish from Zfin; Fly from Flybase; Worm from Wormbase; Dicot from TAIR; Dicty from Dictybase; Yeast from SGD; Pombe from Sanger; Ecoli from EcoliHub.
Organisms with experimental annotations are indicated: EXP, IC, IDA, IEP, IGI, IMP, IPI. In addition, ISS (ISA, ISM, ISO) annotations are so indicated.
Does not include evidence codes: IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Mon Mar 30 18:25:07 2009.

Compare annotations to GO categories for ORTHOMCL13110.

Entry indicates that ortholog exists for this gene.
Colored entries indicate experimental annotation.
Parentheses indicate ISS annotation only.

Category	ID	Term	Human	Mouse	Rat	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli
Molecular Function	GO:0005488	binding	Human	Mouse	Rat	Chicken	Zfish	X	X	X	X	X	X	X
Molecular Function	GO:0030528	transcription regulator activity	Human	Mouse	Rat	Chicken	Zfish	X	X	X	X	X	X	X
Cellular Component	GO:0005623	cell	Human	Mouse	Rat	Chicken	Zfish	X	X	X	X	X	X	X
Cellular Component	GO:0044464	cell part	Human	Mouse	Rat	Chicken	Zfish	X	X	X	X	X	X	X
Cellular Component	GO:0032991	macromolecular complex	Human	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Cellular Component	GO:0031974	membrane-enclosed lumen	Human	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Cellular Component	GO:0043226	organelle	Human	Mouse	Rat	Chicken	Zfish	X	X	X	X	X	X	X
Cellular Component	GO:0044422	organelle part	Human	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Biological Process	GO:0010926	anatomical structure formation	(Human)	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Biological Process	GO:0065007	biological regulation	Human	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Biological Process	GO:0009987	cellular process	Human	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Biological Process	GO:0032502	developmental process	Human	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Biological Process	GO:0051234	establishment of localization	(Human)	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Biological Process	GO:0002376	immune system process	(Human)	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Biological Process	GO:0051179	localization	(Human)	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Biological Process	GO:0008152	metabolic process	Human	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Biological Process	GO:0032501	multicellular organismal process	Human	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Biological Process	GO:0048519	negative regulation of biological process	Human	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Biological Process	GO:0048518	positive regulation of biological process	Human	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Biological Process	GO:0050789	regulation of biological process	Human	Mouse	(Rat)	Chicken	Zfish	X	X	X	X	X	X	X
Biological Process	GO:0050896	response to stimulus	Human	Mouse	Rat	Chicken	Zfish	X	X	X	X	X	X	X

Full set of experimental (and ISS) annotations for ORTHOMCL13110

Category	ID	Term	DB Object	Evidence	With_From	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Nkx2-5	IDA		Mouse	MGI:MGI:84331\|PMID:8900044
Molecular Function	GO:0003677	DNA binding	Nkx2-5	IDA		Mouse	MGI:MGI:2387286\|PMID:12297045
Molecular Function	GO:0003677	DNA binding	Nkx2-5	IDA		Mouse	MGI:MGI:2669059\|PMID:12754203
Molecular Function	GO:0003677	DNA binding	Nkx2-5	IDA		Mouse	MGI:MGI:3055632\|PMID:15363409
Molecular Function	GO:0003677	DNA binding	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Molecular Function	GO:0042301	phosphate binding	P52952	IDA		Human	PMID:9858576
Molecular Function	GO:0042301	phosphate binding	Nkx2-5	ISO	RGD:1606841	Rat	RGD:1624291
Molecular Function	GO:0005515	protein binding	Nkx2-5	IPI	UniProtKB:Q9QZR5	Mouse	MGI:MGI:1303245\|PMID:9748262
Molecular Function	GO:0005515	protein binding	Nkx2-5	IPI	UniProtKB:Q08369\|UniProtKB:Q99593	Mouse	MGI:MGI:3687882\|PMID:12845333
Molecular Function	GO:0005515	protein binding	Nkx2-5	IPI	RGD:620036	Rat	RGD:2289909\|PMID:17544441
Molecular Function	GO:0005515	protein binding	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Molecular Function	GO:0046982	protein heterodimerization activity	Nkx2-5	IPI	UniProtKB:Q61039	Mouse	MGI:MGI:3607868\|PMID:12392994
Molecular Function	GO:0046982	protein heterodimerization activity	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Molecular Function	GO:0042803	protein homodimerization activity	P52952	IPI	UniProtKB:P52952	Human	PMID:18579533
Molecular Function	GO:0042803	protein homodimerization activity	Nkx2-5	IDA		Rat	RGD:2306248\|PMID:11042197
Molecular Function	GO:0042803	protein homodimerization activity	Nkx2-5	ISO	RGD:1606841	Rat	RGD:1624291
Molecular Function	GO:0043565	sequence-specific DNA binding	Nkx2-5	IDA		Rat	RGD:2306248\|PMID:11042197
Molecular Function	GO:0010736	serum response element binding	P52952	ISS	UniProtKB:P42582	Human	PMID:8900537
Molecular Function	GO:0010736	serum response element binding	Nkx2-5	IDA		Mouse	MGI:MGI:83559\|PMID:8887666
Molecular Function	GO:0010736	serum response element binding	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Molecular Function	GO:0032183	SUMO binding	P52952	IPI	UniProtKB:P61956	Human	PMID:18579533
Molecular Function	GO:0032183	SUMO binding	P52952	IPI	UniProtKB:P63165	Human	PMID:18579533
Molecular Function	GO:0032183	SUMO binding	Nkx2-5	ISO	RGD:1606841	Rat	RGD:1624291
Molecular Function	GO:0016563	transcription activator activity	Nkx2-5	IDA		Mouse	MGI:MGI:3040553\|PMID:14978031
Molecular Function	GO:0016563	transcription activator activity	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Molecular Function	GO:0003700	transcription factor activity	P52952	IDA		Human	PMID:11431700
Molecular Function	GO:0003700	transcription factor activity	Nkx2-5	IDA		Mouse	MGI:MGI:2150876\|PMID:11572777
Molecular Function	GO:0003700	transcription factor activity	Nkx2-5	IDA		Mouse	MGI:MGI:84331\|PMID:8900044
Molecular Function	GO:0003700	transcription factor activity	Nkx2-5	IDA		Rat	RGD:727751\|PMID:12824294
Molecular Function	GO:0003700	transcription factor activity	Nkx2-5	IDA		Rat	RGD:1580258\|PMID:12775767
Molecular Function	GO:0003700	transcription factor activity	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Molecular Function	GO:0003700	transcription factor activity	Nkx2-5	ISO	RGD:1606841	Rat	RGD:1624291
Molecular Function	GO:0008134	transcription factor binding	P52952	IPI	UniProtKB:Q99593	Human	PMID:11431700
Molecular Function	GO:0008134	transcription factor binding	P52952	IPI	UniProtKB:P43694	Human	PMID:9858576
Molecular Function	GO:0008134	transcription factor binding	Nkx2-5	ISO	RGD:1606841	Rat	RGD:1624291
Molecular Function	GO:0016564	transcription repressor activity	Nkx2-5	IDA		Mouse	MGI:MGI:2179901\|PMID:12023302
Molecular Function	GO:0016564	transcription repressor activity	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Cellular Component	GO:0005737	cytoplasm	Nkx2-5	IDA		Mouse	MGI:MGI:3828406\|PMID:15653675
Cellular Component	GO:0005737	cytoplasm	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Cellular Component	GO:0005634	nucleus	Nkx2-5	IDA		Mouse	MGI:MGI:2150876\|PMID:11572777
Cellular Component	GO:0005634	nucleus	Nkx2-5	IDA		Mouse	MGI:MGI:1267297\|PMID:9621431
Cellular Component	GO:0005634	nucleus	Nkx2-5	IDA		Rat	RGD:2289909\|PMID:17544441
Cellular Component	GO:0005634	nucleus	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Cellular Component	GO:0005667	transcription factor complex	Nkx2-5	IDA		Mouse	MGI:MGI:2179901\|PMID:12023302
Cellular Component	GO:0005667	transcription factor complex	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0007512	adult heart development	Nkx2-5	IMP	MGI:MGI:1927227	Mouse	MGI:MGI:74918\|PMID:7628699
Biological Process	GO:0007512	adult heart development	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0055014	atrial cardiac muscle cell development	P52952	ISS	UniProtKB:P42582	Human	PMID:8900537
Biological Process	GO:0055014	atrial cardiac muscle cell development	Nkx2-5	IEP		Mouse	PMID:9621431
Biological Process	GO:0055014	atrial cardiac muscle cell development	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0055007	cardiac muscle cell differentiation	Nkx2-5	IMP	MGI:MGI:1857618	Mouse	MGI:MGI:1329801\|PMID:10021345
Biological Process	GO:0055007	cardiac muscle cell differentiation	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0048738	cardiac muscle development	Nkx2-5	IMP	MGI:MGI:1927227	Mouse	MGI:MGI:74918\|PMID:7628699
Biological Process	GO:0048738	cardiac muscle development	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	P52952	IMP		Human	PMID:11889119
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	Nkx2-5	ISO	RGD:1606841	Rat	RGD:1624291
Biological Process	GO:0030154	cell differentiation	Nkx2-5	IGI	MGI:MGI:97351	Mouse	MGI:MGI:2135851\|PMID:11390666
Biological Process	GO:0030154	cell differentiation	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0035050	embryonic heart tube development	Nkx2-5	IGI	MGI:MGI:1888496	Mouse	MGI:MGI:3578574\|PMID:15843414
Biological Process	GO:0035050	embryonic heart tube development	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0007507	heart development	Nkx2-5	IMP	MGI:MGI:1857618	Mouse	MGI:MGI:3039161\|PMID:15085192
Biological Process	GO:0007507	heart development	Nkx2-5	IMP	MGI:MGI:1857618	Mouse	MGI:MGI:1329801\|PMID:10021345
Biological Process	GO:0007507	heart development	Nkx2-5	IGI	MGI:MGI:97351	Mouse	MGI:MGI:2135851\|PMID:11390666
Biological Process	GO:0007507	heart development	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0001947	heart looping	Nkx2-5	IMP	MGI:MGI:1927227	Mouse	MGI:MGI:74918\|PMID:7628699
Biological Process	GO:0001947	heart looping	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0003007	heart morphogenesis	Nkx2-5	IMP	MGI:MGI:1927227	Mouse	MGI:MGI:2153294\|PMID:11784028
Biological Process	GO:0003007	heart morphogenesis	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0030097	hemopoiesis	Nkx2-5	IMP	MGI:MGI:1857618	Mouse	MGI:MGI:1329801\|PMID:10021345
Biological Process	GO:0030097	hemopoiesis	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0043066	negative regulation of apoptosis	Nkx2-5	IGI	MGI:MGI:97351	Mouse	MGI:MGI:2135851\|PMID:11390666
Biological Process	GO:0043066	negative regulation of apoptosis	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptosis	P52952	IMP		Human	PMID:11889119
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptosis	Nkx2-5	IMP		Mouse	MGI:MGI:3784761\|PMID:11889119
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptosis	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptosis	Nkx2-5	ISO	RGD:1606841	Rat	RGD:1624291
Biological Process	GO:0010832	negative regulation of myotube differentiation	P52952	IMP		Human	PMID:15653675
Biological Process	GO:0010832	negative regulation of myotube differentiation	Nkx2-5	ISO	RGD:1606841	Rat	RGD:1624291
Biological Process	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Nkx2-5	IDA		Mouse	MGI:MGI:2179901\|PMID:12023302
Biological Process	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0060037	pharyngeal system development	Nkx2-5	IGI	MGI:MGI:97351	Mouse	MGI:MGI:2135851\|PMID:11390666
Biological Process	GO:0060037	pharyngeal system development	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0051929	positive regulation of calcium ion transport via voltage-gated calcium channel activity	P52952	ISS	UniProtKB:P42582	Human	PMID:8900537
Biological Process	GO:0051929	positive regulation of calcium ion transport via voltage-gated calcium channel activity	Nkx2-5	IMP		Mouse	MGI:MGI:3829107\|PMID:18689573
Biological Process	GO:0051929	positive regulation of calcium ion transport via voltage-gated calcium channel activity	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0051891	positive regulation of cardioblast differentiation	P52952	ISS	UniProtKB:P42582	Human	PMID:8900537
Biological Process	GO:0051891	positive regulation of cardioblast differentiation	Nkx2-5	IMP		Mouse	MGI:MGI:3784761\|PMID:11889119
Biological Process	GO:0051891	positive regulation of cardioblast differentiation	Nkx2-5	IEP		Mouse	PMID:16137232
Biological Process	GO:0051891	positive regulation of cardioblast differentiation	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0008284	positive regulation of cell proliferation	Nkx2-5	IGI	MGI:MGI:97351	Mouse	MGI:MGI:2135851\|PMID:11390666
Biological Process	GO:0008284	positive regulation of cell proliferation	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0045666	positive regulation of neuron differentiation	P52952	IMP		Human	PMID:15653675
Biological Process	GO:0045666	positive regulation of neuron differentiation	Nkx2-5	ISO	RGD:1606841	Rat	RGD:1624291
Biological Process	GO:0010765	positive regulation of sodium ion transport	P52952	ISS	UniProtKB:P42582	Human	PMID:8900537
Biological Process	GO:0010765	positive regulation of sodium ion transport	Nkx2-5	IMP		Mouse	MGI:MGI:3829107\|PMID:18689573
Biological Process	GO:0010765	positive regulation of sodium ion transport	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0045885	positive regulation of survival gene product expression	P52952	IMP		Human	PMID:18079734
Biological Process	GO:0045885	positive regulation of survival gene product expression	Nkx2-5	ISO	RGD:1606841	Rat	RGD:1624291
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Nkx2-5	IGI	MGI:MGI:1347465	Mouse	MGI:MGI:3055632\|PMID:15363409
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Nkx2-5	IGI	MGI:MGI:98493	Mouse	MGI:MGI:3621085\|PMID:16556915
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Nkx2-5	IGI	MGI:MGI:103580	Mouse	MGI:MGI:3607868\|PMID:12392994
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Nkx2-5	IDA		Mouse	MGI:MGI:3614736\|PMID:16380715
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Nkx2-5	IDA		Mouse	MGI:MGI:84331\|PMID:8900044
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Nkx2-5	ISO	UniProtKB:P52952	Mouse	MGI:MGI:2154458
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	P52952	ISS	UniProtKB:P42582	Human	PMID:8900537
Biological Process	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	Nkx2-5	IDA		Mouse	MGI:MGI:83559\|PMID:8887666
Biological Process	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0010735	positive regulation of transcription via serum response element binding	P52952	ISS	UniProtKB:P42582	Human	PMID:8900537
Biological Process	GO:0010735	positive regulation of transcription via serum response element binding	Nkx2-5	IDA		Mouse	MGI:MGI:83559\|PMID:8887666
Biological Process	GO:0010735	positive regulation of transcription via serum response element binding	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0045893	positive regulation of transcription, DNA-dependent	Nkx2-5	IDA		Mouse	MGI:MGI:2150876\|PMID:11572777
Biological Process	GO:0045893	positive regulation of transcription, DNA-dependent	Nkx2-5	IDA		Mouse	MGI:MGI:3040553\|PMID:14978031
Biological Process	GO:0045893	positive regulation of transcription, DNA-dependent	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0055117	regulation of cardiac muscle contraction	P52952	ISS	UniProtKB:P42582	Human	PMID:8900537
Biological Process	GO:0055117	regulation of cardiac muscle contraction	Nkx2-5	IMP		Mouse	MGI:MGI:3829107\|PMID:18689573
Biological Process	GO:0055117	regulation of cardiac muscle contraction	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0006357	regulation of transcription from RNA polymerase II promoter	Nkx2-5	IDA		Mouse	MGI:MGI:2682181\|PMID:14645532
Biological Process	GO:0006357	regulation of transcription from RNA polymerase II promoter	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0032355	response to estradiol stimulus	Nkx2-5	IEP		Rat	RGD:2306247\|PMID:18832095
Biological Process	GO:0048536	spleen development	P52952	ISS	UniProtKB:P42582	Human	PMID:8900537
Biological Process	GO:0048536	spleen development	Nkx2-5	IEP		Mouse	PMID:9621431
Biological Process	GO:0048536	spleen development	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0030878	thyroid gland development	P52952	IMP		Human	PMID:16418214
Biological Process	GO:0030878	thyroid gland development	Nkx2-5	IMP		Mouse	MGI:MGI:3828401\|PMID:16418214
Biological Process	GO:0030878	thyroid gland development	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0030878	thyroid gland development	Nkx2-5	ISO	RGD:1606841	Rat	RGD:1624291
Biological Process	GO:0043586	tongue development	P52952	ISS	UniProtKB:P42582	Human	PMID:8900537
Biological Process	GO:0043586	tongue development	Nkx2-5	IEP		Mouse	PMID:9621431
Biological Process	GO:0043586	tongue development	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0001570	vasculogenesis	Nkx2-5	IMP	MGI:MGI:1857618	Mouse	MGI:MGI:1329801\|PMID:10021345
Biological Process	GO:0001570	vasculogenesis	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291
Biological Process	GO:0055015	ventricular cardiac muscle cell development	P52952	ISS	UniProtKB:P42582	Human	PMID:8900537
Biological Process	GO:0055015	ventricular cardiac muscle cell development	Nkx2-5	IEP		Mouse	PMID:9621431
Biological Process	GO:0055015	ventricular cardiac muscle cell development	Nkx2-5	ISO	RGD:731878	Rat	RGD:1624291

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)