MGI MouseCyc MP annotations for URSIN-PWY

MGI MouseCyc experimental MP annotations for ureide biosynthesis

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for ureide biosynthesis

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005375	adipose tissue phenotype	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005386	behavior/neurological phenotype	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005385	cardiovascular system phenotype	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005379	endocrine/exocrine gland phenotype	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005378	growth/size phenotype	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005397	hematopoietic system phenotype	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005376	homeostasis/metabolism phenotype	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005387	immune system phenotype	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005373	lethality-postnatal	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005374	lethality-prenatal/perinatal	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005372	life span-post-weaning/aging	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005369	muscle phenotype	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005367	renal/urinary system phenotype	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh
MP:0005389	reproductive system phenotype	1190003J15Rik	Impdh1	Impdh2	Nt5c1b	Nt5c2	Nt5dc2	Nt5e	Pnp1	Pnp2	Uox	Xdh

Full set of annotations for ureide biosynthesis

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0000179	abnormal blood chemistry	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0000179	abnormal blood chemistry	Xdh	Xdh^tm1Fink/Xdh^tm1Fink	involves: 129X1/SvJ * C57BL/6J	color key
MP:0005078	abnormal cytotoxic T cell physiology	Impdh1	Impdh1^tm1Bmi/Impdh1^tm1Bmi,Impdh2^tm1Bmi/Impdh2⁺	involves: 129/Sv * C57BL/6	color key
MP:0005078	abnormal cytotoxic T cell physiology	Impdh2	Hprt1^b-m3/Y,Impdh2^tm1Bmi/Impdh2⁺	involves: 129P2/OlaHsd	color key
MP:0005078	abnormal cytotoxic T cell physiology	Impdh2	Impdh1^tm1Bmi/Impdh1^tm1Bmi,Impdh2^tm1Bmi/Impdh2⁺	involves: 129/Sv * C57BL/6	color key
MP:0005584	abnormal enzyme/coenzyme activity	Pnp1	Pnp1^e/Pnp1^e	involves: C3H/HeHa * C57BL/6J	color key
MP:0005584	abnormal enzyme/coenzyme activity	Pnp1	Pnp1^f/Pnp1^f	involves: C3H/HeHa * C57BL/6J	color key
MP:0005584	abnormal enzyme/coenzyme activity	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0005584	abnormal enzyme/coenzyme activity	Pnp1	Pnp1^h/Pnp1^h	involves: C3H/HeHa * C57BL/6J	color key
MP:0005584	abnormal enzyme/coenzyme activity	Pnp1	Pnp1ⁱ/Pnp1ⁱ	involves: C3H/HeHa * C57BL/6J	color key
MP:0000716	abnormal immune system cell morphology	Impdh1	Impdh1^tm1Bmi/Impdh1^tm1Bmi	involves: 129/Sv * C57BL/6	color key
MP:0000716	abnormal immune system cell morphology	Impdh1	Impdh1^tm1Bmi/Impdh1^tm1Bmi,Impdh2^tm1Bmi/Impdh2⁺	involves: 129/Sv * C57BL/6	color key
MP:0000716	abnormal immune system cell morphology	Impdh2	Impdh1^tm1Bmi/Impdh1^tm1Bmi,Impdh2^tm1Bmi/Impdh2⁺	involves: 129/Sv * C57BL/6	color key
MP:0006271	abnormal involution of the mammary gland	Xdh	Xdh^tm1Mrc/Xdh⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0005555	abnormal kidney excretion	Pnp1	Pnp1^e/Pnp1^e	involves: C3H/HeHa * C57BL/6J	color key
MP:0005555	abnormal kidney excretion	Pnp1	Pnp1^f/Pnp1^f	involves: C3H/HeHa * C57BL/6J	color key
MP:0002135	abnormal kidney morphology	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002135	abnormal kidney morphology	Uox	Uoxⁱⁿ/Uoxⁱⁿ	involves: C57BL/6J * DBA/2J	color key
MP:0002135	abnormal kidney morphology	Xdh	Xdh^tm1Fink/Xdh^tm1Fink	involves: 129X1/SvJ * C57BL/6J	color key
MP:0002136	abnormal kidney physiology	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001882	abnormal lactation	Xdh	Xdh^tm1Mrc/Xdh⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0000217	abnormal leukocyte cell number	Pnp1	Pnp1^f/Pnp1^f	C57BL/6J-Pnp1	color key
MP:0000217	abnormal leukocyte cell number	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0000717	abnormal lymphocyte cell number	Impdh2	Hprt1^b-m3/Y,Impdh2^tm1Bmi/Impdh2⁺	involves: 129P2/OlaHsd	color key
MP:0000717	abnormal lymphocyte cell number	Impdh2	Impdh2^tm1Bmi/Impdh2⁺	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002401	abnormal lymphopoiesis	Impdh1	Impdh1^tm1Bmi/Impdh1^tm1Bmi,Impdh2^tm1Bmi/Impdh2⁺	involves: 129/Sv * C57BL/6	color key
MP:0002401	abnormal lymphopoiesis	Impdh1	Hprt1^b-m3/Y,Impdh1^tm1Bmi/Impdh1^tm1Bmi	involves: 129/Sv * C57BL/6	color key
MP:0002401	abnormal lymphopoiesis	Impdh2	Impdh1^tm1Bmi/Impdh1^tm1Bmi,Impdh2^tm1Bmi/Impdh2⁺	involves: 129/Sv * C57BL/6	color key
MP:0006270	abnormal mammary gland growth during lactation	Xdh	Xdh^tm1Mrc/Xdh⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0004047	abnormal milk composition	Xdh	Xdh^tm1Mrc/Xdh⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0003881	abnormal nephron morphology	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0005464	abnormal platelet physiology	Nt5e	Nt5e^tm1Jsc/Nt5e^tm1Jsc	involves: 129S1/Sv * 129X1/SvJ * NMRI	color key
MP:0005325	abnormal renal glomerulus morphology	Uox	Uoxⁱⁿ/Uoxⁱⁿ	involves: C57BL/6J * DBA/2J	color key
MP:0005325	abnormal renal glomerulus morphology	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002703	abnormal renal tubule morphology	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0005529	abnormal renal vascular resistance	Nt5e	Nt5e^tm1Jgsc/Nt5e^tm1Jgsc	involves: 129S/SvEv * C57BL/6J	color key
MP:0003638	abnormal response/metabolism to endogenous compounds	Nt5e	Nt5e^tm1Jgsc/Nt5e^tm1Jgsc	involves: 129S/SvEv * C57BL/6J	color key
MP:0003638	abnormal response/metabolism to endogenous compounds	Nt5e	Nt5e^tm1Lft/Nt5e^tm1Lft	involves: 129S1/Sv * C57BL/6	color key
MP:0000759	abnormal skeletal muscle morphology	Xdh	Xdh^tm1Mrc/Xdh⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0002365	abnormal thymus cellularity	Pnp1	Pnp1^e/Pnp1^e	C57BL/6J-Pnp1	color key
MP:0002365	abnormal thymus cellularity	Pnp1	Pnp1^f/Pnp1^f	C57BL/6J-Pnp1	color key
MP:0002365	abnormal thymus cellularity	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0000538	abnormal urinary bladder morphology	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001757	abnormal urine chemistry	Uox	Uoxⁱⁿ/Uoxⁱⁿ	involves: C57BL/6J * DBA/2J	color key
MP:0001757	abnormal urine chemistry	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0003619	abnormal urine color	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002502	abnormal vasoactive mediator physiology	Nt5e	Nt5e^tm1Jsc/Nt5e^tm1Jsc	involves: 129S1/Sv * 129X1/SvJ * NMRI	color key
MP:0000343	altered response to myocardial infarction	Nt5e	Nt5e^tm1Lft/Nt5e^tm1Lft	involves: 129S1/Sv * C57BL/6	color key
MP:0002499	chronic inflammation	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002499	chronic inflammation	Uox	Uoxⁱⁿ/Uoxⁱⁿ	involves: C57BL/6J * DBA/2J	color key
MP:0005095	decreased T cell proliferation	Impdh1	Impdh1^tm1Bmi/Impdh1^tm1Bmi	involves: 129/Sv * C57BL/6	color key
MP:0008079	decreased CD8-positive T cell number	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0005454	decreased adipose tissue amount	Xdh	Xdh^tm1Mrc/Xdh⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0005095	decreased T cell proliferation	Impdh1	Hprt1^b-m3/Y,Impdh1^tm1Bmi/Impdh1^tm1Bmi	involves: 129/Sv * C57BL/6	color key
MP:0005607	decreased bleeding time	Nt5e	Nt5e^tm1Jsc/Nt5e^tm1Jsc	involves: 129S1/Sv * 129X1/SvJ * NMRI	color key
MP:0001265	decreased body size	Xdh	Xdh^tm1Mrc/Xdh^tm1Mrc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0005095	decreased T cell proliferation	Impdh2	Impdh1^tm1Bmi/Impdh1^tm1Bmi,Impdh2^tm1Bmi/Impdh2⁺	involves: 129/Sv * C57BL/6	color key
MP:0001262	decreased body weight	Xdh	Xdh^tm1Mrc/Xdh⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0008079	decreased CD8-positive T cell number	Pnp1	Pnp1^f/Pnp1^f	C57BL/6J-Pnp1	color key
MP:0003023	decreased coronary flow rate	Nt5e	Nt5e^tm1Jsc/Nt5e^tm1Jsc	involves: 129S1/Sv * 129X1/SvJ * NMRI	color key
MP:0005092	decreased double-positive T cell number	Pnp1	Pnp1^f/Pnp1^f	C57BL/6J-Pnp1	color key
MP:0005092	decreased double-positive T cell number	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0008700	decreased interleukin-4 secretion	Impdh1	Hprt1^b-m3/Y,Impdh1^tm1Bmi/Impdh1^tm1Bmi	involves: 129/Sv * C57BL/6	color key
MP:0005095	decreased T cell proliferation	Impdh1	Impdh1^tm1Bmi/Impdh1^tm1Bmi,Impdh2^tm1Bmi/Impdh2⁺	involves: 129/Sv * C57BL/6	color key
MP:0002988	decreased urine osmolality	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0005079	defective cytotoxic T cell cytolysis	Impdh1	Hprt1^b-m3/Y,Impdh1^tm1Bmi/Impdh1^tm1Bmi	involves: 129/Sv * C57BL/6	color key
MP:0004860	dilated kidney collecting duct	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0003670	dilated renal glomerular capsule	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002705	dilated renal tubules	Uox	Uoxⁱⁿ/Uoxⁱⁿ	involves: C57BL/6J * DBA/2J	color key
MP:0002705	dilated renal tubules	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001785	edema	Nt5e	Nt5e^tm1Lft/Nt5e^tm1Lft	involves: 129S1/Sv * C57BL/6	color key
MP:0006204	embryonic lethality before implantation	Impdh2	Impdh2^tm1Bmi/Impdh2^tm1Bmi	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0006207	embryonic lethality during organogenesis	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6J	color key
MP:0000519	hydronephrosis	Uox	Uoxⁱⁿ/Uoxⁱⁿ	involves: C57BL/6J * DBA/2J	color key
MP:0000519	hydronephrosis	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001357	increased aggression toward humans	Nt5e	Nt5e^tm1Lft/Nt5e^tm1Lft	involves: 129S1/Sv * C57BL/6	color key
MP:0005565	increased blood urea nitrogen level	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0005565	increased blood urea nitrogen level	Uox	Uoxⁱⁿ/Uoxⁱⁿ	involves: C57BL/6J * DBA/2J	color key
MP:0005565	increased blood urea nitrogen level	Xdh	Xdh^tm1Fink/Xdh^tm1Fink	involves: 129X1/SvJ * C57BL/6J	color key
MP:0002968	increased circulating alkaline phosphatase level	Nt5e	Nt5e^tm1Jgsc/Nt5e^tm1Jgsc	involves: 129S/SvEv * C57BL/6J	color key
MP:0005553	increased circulating creatinine level	Uox	Uoxⁱⁿ/Uoxⁱⁿ	involves: C57BL/6J * DBA/2J	color key
MP:0005090	increased double-negative T cell number	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0005090	increased double-negative T cell number	Pnp1	Pnp1^f/Pnp1^f	involves: C3H/HeHa * C57BL/6J	color key
MP:0003037	increased infarction size	Nt5e	Nt5e^tm1Lft/Nt5e^tm1Lft	involves: 129S1/Sv * C57BL/6	color key
MP:0003070	increased vascular permeability	Nt5e	Nt5e^tm1Lft/Nt5e^tm1Lft	involves: 129S1/Sv * C57BL/6	color key
MP:0000522	kidney cortex cysts	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0003675	kidney cysts	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002708	kidney stones	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0005202	lethargy	Nt5e	Nt5e^tm1Lft/Nt5e^tm1Lft	involves: 129S1/Sv * C57BL/6	color key
MP:0001426	polydipsia	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001762	polyuria	Uox	Uoxⁱⁿ/Uoxⁱⁿ	involves: C57BL/6J * DBA/2J	color key
MP:0001762	polyuria	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002082	postnatal lethality	Uox	Uoxⁱⁿ/Uoxⁱⁿ	involves: C57BL/6J * DBA/2J	color key
MP:0002082	postnatal lethality	Xdh	Xdh^tm1Fink/Xdh^tm1Fink	involves: 129X1/SvJ * C57BL/6J	color key
MP:0002083	premature death	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002083	premature death	Xdh	Xdh^tm1Mrc/Xdh^tm1Mrc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0002080	prenatal lethality	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0003985	renal fibrosis	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002989	small kidney	Uox	Uox^tm1Bay/Uox^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0005048	thrombosis	Nt5e	Nt5e^tm1Jsc/Nt5e^tm1Jsc	involves: 129S1/Sv * 129X1/SvJ * NMRI	color key