MGI MouseCyc MP annotations for TYRFUMCAT-PWY

MGI MouseCyc experimental MP annotations for tyrosine degradation I

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for tyrosine degradation I

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Fah	Fahd1	Fahd2a	Gstz1	Hgd	Hpd	Tat
MP:0005385	cardiovascular system phenotype	Fah	Fahd1	Fahd2a	Gstz1	Hgd	Hpd	Tat
MP:0005384	cellular phenotype	Fah	Fahd1	Fahd2a	Gstz1	Hgd	Hpd	Tat
MP:0005378	growth/size phenotype	Fah	Fahd1	Fahd2a	Gstz1	Hgd	Hpd	Tat
MP:0005397	hematopoietic system phenotype	Fah	Fahd1	Fahd2a	Gstz1	Hgd	Hpd	Tat
MP:0005376	homeostasis/metabolism phenotype	Fah	Fahd1	Fahd2a	Gstz1	Hgd	Hpd	Tat
MP:0005387	immune system phenotype	Fah	Fahd1	Fahd2a	Gstz1	Hgd	Hpd	Tat
MP:0005373	lethality-postnatal	Fah	Fahd1	Fahd2a	Gstz1	Hgd	Hpd	Tat
MP:0005374	lethality-prenatal/perinatal	Fah	Fahd1	Fahd2a	Gstz1	Hgd	Hpd	Tat
MP:0005372	life span-post-weaning/aging	Fah	Fahd1	Fahd2a	Gstz1	Hgd	Hpd	Tat
MP:0005370	liver/biliary system phenotype	Fah	Fahd1	Fahd2a	Gstz1	Hgd	Hpd	Tat
MP:0005367	renal/urinary system phenotype	Fah	Fahd1	Fahd2a	Gstz1	Hgd	Hpd	Tat

Full set of annotations for tyrosine degradation I

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0005311	abnormal circulating amino acid level	Fah	Fah^tm1Mgo/Fah^tm1Mgo	involves: 129/Sv * PT	color key
MP:0005311	abnormal circulating amino acid level	Fah	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0005311	abnormal circulating amino acid level	Hgd	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0005311	abnormal circulating amino acid level	Hpd	Hpd^hty/Hpd^hty	ICRIII	color key
MP:0000203	abnormal circulating aspartate transaminase level	Fah	Fah^tm1Mgo/Fah^tm1Mgo	either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6J)	color key
MP:0000607	abnormal hepatocyte morphology	Fah	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0000607	abnormal hepatocyte morphology	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0000607	abnormal hepatocyte morphology	Hgd	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0001657	abnormal induced morbidity/mortality	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0001657	abnormal induced morbidity/mortality	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0002135	abnormal kidney morphology	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0000598	abnormal liver morphology	Fah	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0000598	abnormal liver morphology	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0000598	abnormal liver morphology	Hgd	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0000609	abnormal liver physiology	Fah	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0000609	abnormal liver physiology	Fah	Fah^tm1Mgo/Fah^tm1Mgo	involves: 129/Sv * PT	color key
MP:0000609	abnormal liver physiology	Hgd	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0002703	abnormal renal tubule morphology	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0001757	abnormal urine chemistry	Fah	Fah^5961SB/Fah^5961SB	BALB/cRl	color key
MP:0001757	abnormal urine chemistry	Fah	Fah^6287SB/Fah^6287SB	BALB/cRl	color key
MP:0001757	abnormal urine chemistry	Hpd	Hpd^hty/Hpd^hty	ICRIII	color key
MP:0003619	abnormal urine color	Hgd	Hgd^aku/Hgd^aku	either: (involves: 129/Sv * BALB/cByJ * PT) or (involves: 129/Sv * C57BL/6J * PT)	color key
MP:0003311	aminoaciduria	Hgd	Hgd^aku/Hgd^aku	either: (involves: 129/Sv * BALB/cByJ * PT) or (involves: 129/Sv * C57BL/6J * PT)	color key
MP:0000316	cellular necrosis	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0002499	chronic inflammation	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0001262	decreased body weight	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0000221	decreased leukocyte cell number	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0004953	decreased spleen weight	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0002705	dilated renal tubules	Fah	Fah^tm1Mgo/Fah^tm1Mgo	involves: 129/Sv * PT	color key
MP:0002705	dilated renal tubules	Fah	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0002705	dilated renal tubules	Hgd	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0002837	dystrophic cardiac calcinosis	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0001654	hepatic necrosis	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0001654	hepatic necrosis	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0002628	hepatic steatosis	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0002628	hepatic steatosis	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0000189	hypoglycemia	Fah	Fah^tm1Mgo/Fah^tm1Mgo	either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6J)	color key
MP:0005553	increased circulating creatinine level	Fah	Fah^tm1Mgo/Fah^tm1Mgo	either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6J)	color key
MP:0003917	increased kidney weight	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0002981	increased liver weight	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0000611	jaundice	Fah	Fah^tm1Mgo/Fah^tm1Mgo	involves: 129/Sv * PT	color key
MP:0000611	jaundice	Fah	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0000611	jaundice	Hgd	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0002893	ketoaciduria	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0001859	kidney inflammation	Fah	Fah^tm1Mgo/Fah^tm1Mgo	involves: 129/Sv * PT	color key
MP:0001859	kidney inflammation	Fah	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0001859	kidney inflammation	Hgd	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0001860	liver inflammation	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0002058	neonatal lethality	Fah	Fah^tm1Mgo/Fah^tm1Mgo	either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6J)	color key
MP:0002058	neonatal lethality	Fah	Fah^5961SB/Fah^5961SB	BALB/cRl	color key
MP:0003674	oxidative stress	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0000603	pale liver	Fah	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0000603	pale liver	Fah	Fah^tm1Mgo/Fah^tm1Mgo	involves: 129/Sv * PT	color key
MP:0000603	pale liver	Hgd	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0002082	postnatal lethality	Fah	Fah^6287SB/Fah^6287SB	BALB/cRl	color key
MP:0002083	premature death	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0001263	weight loss	Fah	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key
MP:0001263	weight loss	Fah	Fah^tm1Mgo/Fah^tm1Mgo	involves: 129/Sv * PT	color key
MP:0001263	weight loss	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0001263	weight loss	Hgd	Fah^tm1Mgo/Fah^tm1Mgo,Hgd^aku/Hgd⁺	involves: 129/Sv * PT	color key