MGI MouseCyc MP annotations for THIOREDOX-PWY

MGI MouseCyc experimental MP annotations for thioredoxin pathway

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for thioredoxin pathway

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Txnrd1	Txnrd2	Txnrd3
MP:0005386	behavior/neurological phenotype	Txnrd1	Txnrd2	Txnrd3
MP:0005385	cardiovascular system phenotype	Txnrd1	Txnrd2	Txnrd3
MP:0005384	cellular phenotype	Txnrd1	Txnrd2	Txnrd3
MP:0005380	embryogenesis phenotype	Txnrd1	Txnrd2	Txnrd3
MP:0005378	growth/size phenotype	Txnrd1	Txnrd2	Txnrd3
MP:0005397	hematopoietic system phenotype	Txnrd1	Txnrd2	Txnrd3
MP:0005376	homeostasis/metabolism phenotype	Txnrd1	Txnrd2	Txnrd3
MP:0005374	lethality-prenatal/perinatal	Txnrd1	Txnrd2	Txnrd3
MP:0005370	liver/biliary system phenotype	Txnrd1	Txnrd2	Txnrd3
MP:0005369	muscle phenotype	Txnrd1	Txnrd2	Txnrd3
MP:0003631	nervous system phenotype	Txnrd1	Txnrd2	Txnrd3
MP:0002873	normal phenotype	Txnrd1	Txnrd2	Txnrd3

Full set of annotations for thioredoxin pathway

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0002182	abnormal astrocyte morphology	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0000233	abnormal blood flow velocity	Txnrd2	Txnrd2^tm1.1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0004097	abnormal cerebellar cortex morphology	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0006097	abnormal cerebellar lobule formation	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0000854	abnormal cerebellum development	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0001675	abnormal ectoderm development	Txnrd1	Txnrd1^tm1.1Ees/Txnrd1^tm1.1Ees	B6.129X1-Txnrd1	color key
MP:0001672	abnormal embryogenesis/ development	Txnrd1	Txnrd1^tm1.1Ees/Txnrd1^tm1.1Ees	B6.129X1-Txnrd1	color key
MP:0003567	abnormal fetal cardiomyocyte proliferation	Txnrd2	Txnrd2^tm1.1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0008572	abnormal Purkinje cell dendrite morphology	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0000849	abnormal cerebellum morphology	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0001724	abnormal extraembryonic endoderm formation	Txnrd1	Txnrd1^tm1.1Ees/Txnrd1^tm1.1Ees	B6.129X1-Txnrd1	color key
MP:0001406	abnormal gait	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0003634	abnormal glial cell morphology	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0000266	abnormal heart morphology	Txnrd2	Txnrd2^tm1.1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0000277	abnormal heart shape	Txnrd2	Myl2^tm1(cre)Krc/Myl2⁺,Txnrd2^tm1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002123	abnormal hematopoiesis	Txnrd2	Txnrd2^tm1.1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0000598	abnormal liver morphology	Txnrd2	Myl2^tm1(cre)Krc/Myl2⁺,Txnrd2^tm1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0000598	abnormal liver morphology	Txnrd2	Txnrd2^tm1.1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0000278	abnormal myocardial fiber morphology	Txnrd2	Myl2^tm1(cre)Krc/Myl2⁺,Txnrd2^tm1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002151	abnormal neural tube morphology/development	Txnrd1	Txnrd1^tm1.1Marc/Txnrd1^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0005221	abnormal rostral-caudal axis patterning	Txnrd1	Txnrd1^tm1.1Marc/Txnrd1^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0001688	abnormal somite development	Txnrd1	Txnrd1^tm1.1Marc/Txnrd1^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0005033	abnormal trophoblast giant cells	Txnrd1	Txnrd1^tm1.1Ees/Txnrd1^tm1.1Ees	B6.129X1-Txnrd1	color key
MP:0000281	abnormal ventricular septum morphology	Txnrd2	Txnrd2^tm1.1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001718	abnormal yolk sac morphology	Txnrd1	Txnrd1^tm1.1Marc/Txnrd1^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0001577	anemia	Txnrd2	Txnrd2^tm1.1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001393	ataxia	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0000851	cerebellum hypoplasia	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0006138	congestive heart failure	Txnrd2	Myl2^tm1(cre)Krc/Myl2⁺,Txnrd2^tm1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001265	decreased body size	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0000352	decreased cell proliferation	Txnrd1	Txnrd1^tm1.1Marc/Txnrd1^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0000352	decreased cell proliferation	Txnrd2	Txnrd2^tm1.1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0003140	dilated atria	Txnrd2	Myl2^tm1(cre)Krc/Myl2⁺,Txnrd2^tm1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0000885	ectopic Purkinje cell	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0001785	edema	Txnrd2	Myl2^tm1(cre)Krc/Myl2⁺,Txnrd2^tm1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001730	embryonic growth arrest	Txnrd1	Txnrd1^tm1.1Marc/Txnrd1^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0001730	embryonic growth arrest	Txnrd1	Txnrd1^tm1.1Ees/Txnrd1^tm1.1Ees	B6.129X1-Txnrd1	color key
MP:0006206	embryonic lethality before turning of embryo	Txnrd1	Txnrd1^tm1.1Ees/Txnrd1^tm1.1Ees	B6.129X1-Txnrd1	color key
MP:0006207	embryonic lethality during organogenesis	Txnrd1	Txnrd1^tm1.1Marc/Txnrd1^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0006207	embryonic lethality during organogenesis	Txnrd2	Txnrd2^tm1.1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0004180	failure of initiation of embryo turning	Txnrd1	Txnrd1^tm1.1Marc/Txnrd1^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0001693	failure of primitive streak formation	Txnrd1	Txnrd1^tm1.1Ees/Txnrd1^tm1.1Ees	B6.129X1-Txnrd1	color key
MP:0001696	failure to gastrulate	Txnrd1	Txnrd1^tm1.1Ees/Txnrd1^tm1.1Ees	B6.129X1-Txnrd1	color key
MP:0001525	impaired balance	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0001405	impaired coordination	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0002058	neonatal lethality	Txnrd2	Myl2^tm1(cre)Krc/Myl2⁺,Txnrd2^tm1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002169	no abnormal phenotype detected	Txnrd2	Txnrd2^tm1Marc/Txnrd2^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0000295	poorly developed ventricular trabeculae	Txnrd2	Txnrd2^tm1.1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0008489	postnatal slow weight gain	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0001698	reduced embryo size	Txnrd1	Txnrd1^tm1.1Marc/Txnrd1^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6J	color key
MP:0000873	thin external granule cell layer	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key
MP:0000280	thin ventricular wall	Txnrd2	Txnrd2^tm1.1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0000280	thin ventricular wall	Txnrd2	Myl2^tm1(cre)Krc/Myl2⁺,Txnrd2^tm1Marc/Txnrd2^tm1.1Marc	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0000745	tremors	Txnrd1	Txnrd1^tm1Marc/Txnrd1^tm1Marc,Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	color key