MGI MouseCyc MP annotations for PWY3DJ-4

MGI MouseCyc experimental MP annotations for biosynthesis of corticosteroids

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for biosynthesis of corticosteroids

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005386	behavior/neurological phenotype	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005385	cardiovascular system phenotype	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005384	cellular phenotype	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005382	craniofacial phenotype	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005380	embryogenesis phenotype	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005379	endocrine/exocrine gland phenotype	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005378	growth/size phenotype	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005397	hematopoietic system phenotype	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005376	homeostasis/metabolism phenotype	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005387	immune system phenotype	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005374	lethality-prenatal/perinatal	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005372	life span-post-weaning/aging	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005369	muscle phenotype	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0003631	nervous system phenotype	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3
MP:0005389	reproductive system phenotype	Cyp11a1	Cyp11b1	Cyp21a1	Fdx1	G6pd2	G6pdx	H6pd	Hsd3b1	Hsd3b3

Full set of annotations for biosynthesis of corticosteroids

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0008288	abnormal adrenal cortex morphology	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0008288	abnormal adrenal cortex morphology	Cyp11a1	Cyp11a1^tm2Bcc/Cyp11a1^tm2Bcc	Not Specified	color key
MP:0000639	abnormal adrenal gland morphology	Cyp11a1	Cyp11a1^tm2Bcc/Cyp11a1^tm2Bcc	Not Specified	color key
MP:0002909	abnormal adrenal gland physiology	Cyp11a1	Cyp11a1^tm2Bcc/Cyp11a1^tm2Bcc	Not Specified	color key
MP:0002836	abnormal chorion morphology	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0002836	abnormal chorion morphology	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0005418	abnormal circulating hormone level	Cyp11a1	Cyp11a1^tm2Bcc/Cyp11a1^tm2Bcc	Not Specified	color key
MP:0002668	abnormal circulating potassium level	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0001776	abnormal circulating sodium level	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0001700	abnormal embryo turning	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0004261	abnormal embryonic neuroepithelium morphology	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0004261	abnormal embryonic neuroepithelium morphology	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0002085	abnormal embryonic tissue morphology	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0005584	abnormal enzyme/coenzyme activity	H6pd	H6pd^tm1Pmst/H6pd^tm1Pmst	involves: 129P2/OlaHsd	color key
MP:0005584	abnormal enzyme/coenzyme activity	H6pd	H6pd^tm1Pmst/H6pd^tm1Pmst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0004933	abnormal epididymis epithelium morphology	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0002631	abnormal epididymis morphology	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0002447	abnormal erythrocyte morphology	G6pdx	G6pdx^a-m1Neu/Y	involves: 101/El * C3H/El * T-stock	color key
MP:0003656	abnormal erythrocyte physiology	G6pdx	G6pdx^a-m1Neu/Y	involves: 101/El * C3H/El * T-stock	color key
MP:0002086	abnormal extraembryonic tissue morphology	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0002086	abnormal extraembryonic tissue morphology	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0005449	abnormal food intake	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0000432	abnormal head morphology	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0000266	abnormal heart morphology	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0000266	abnormal heart morphology	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0005563	abnormal hemoglobin content	G6pdx	G6pdx^a-m1Neu/Y	involves: 101/El * C3H/El * T-stock	color key
MP:0001547	abnormal lipid level	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0006301	abnormal mesenchyme morphology	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0006035	abnormal mitochondrial morphology	Cyp11a1	Cyp11a1^tm2Bcc/Cyp11a1^tm2Bcc	Not Specified	color key
MP:0001716	abnormal placenta labyrinth morphology	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0003186	abnormal redox activity	G6pdx	G6pdx^a-m1Neu/Y	involves: 101/El * C3H/El * T-stock	color key
MP:0003638	abnormal response/metabolism to endogenous compounds	H6pd	H6pd^tm1Pmst/H6pd^tm1Pmst	involves: 129P2/OlaHsd	color key
MP:0002216	abnormal seminiferous tubule morphology	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0001688	abnormal somite development	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0001156	abnormal spermatogenesis	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0004255	abnormal spongiotrophoblast layer morphology	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0001146	abnormal testis morphology	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0002769	abnormal vas deferens morphology	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0001614	abnormal vasculature	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0001614	abnormal vasculature	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0008294	abnormal zona fasciculata morphology	Cyp11a1	Cyp11a1^tm2Bcc/Cyp11a1^tm2Bcc	Not Specified	color key
MP:0008293	abnormal zona glomerulosa morphology	Cyp11a1	Cyp11a1^tm2Bcc/Cyp11a1^tm2Bcc	Not Specified	color key
MP:0002770	absent bulbourethral gland	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0002771	absent coagulating gland	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0001159	absent prostate gland	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0002670	absent scrotum	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0000343	altered response to myocardial infarction	G6pdx	G6pdx^a-m1Neu/Y	involves: 101/El * C3H/El * T-stock	color key
MP:0000343	altered response to myocardial infarction	G6pdx	G6pdx^a-m1Neu/G6pdx^a-m1Neu	involves: 101/El * C3H/El * T-stock	color key
MP:0001577	anemia	G6pdx	G6pdx^a-m1Neu/Y	involves: 101/El * C3H/El * T-stock	color key
MP:0005602	decreased angiogenesis	G6pdx	G6pdx^a-m1Neu/Y	involves: 101/El * C3H/El * T-stock	color key
MP:0002667	decreased circulating aldosterone level	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0002665	decreased circulating corticosterone level	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0002665	decreased circulating corticosterone level	Cyp11a1	Cyp11a1^tm2Bcc/Cyp11a1^tm2Bcc	Not Specified	color key
MP:0002665	decreased circulating corticosterone level	H6pd	H6pd^tm1Pmst/H6pd^tm1Pmst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0006414	decreased T cell apoptosis	Cyp11a1	Cyp11a1^tm2Bcc/Cyp11a1^tm2Bcc	Not Specified	color key
MP:0002875	decreased erythrocyte cell number	G6pdx	G6pdx^a-m1Neu/Y	involves: 101/El * C3H/El * T-stock	color key
MP:0005562	decreased mean corpuscular hemoglobin	G6pdx	G6pdx^a-m1Neu/Y	involves: 101/El * C3H/El * T-stock	color key
MP:0008770	decreased survivor rate	Cyp11a1	Cyp11a1^tm2Bcc/Cyp11a1^tm2Bcc	Not Specified	color key
MP:0001730	embryonic growth arrest	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0006207	embryonic lethality during organogenesis	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0006207	embryonic lethality during organogenesis	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0000642	enlarged adrenal glands	Cyp11a1	Cyp11a1^tm2Bcc/Cyp11a1^tm2Bcc	Not Specified	color key
MP:0000642	enlarged adrenal glands	H6pd	H6pd^tm1Pmst/H6pd^tm1Pmst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0000646	enlarged adrenocortical cells	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0001914	hemorrhage	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0001914	hemorrhage	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0001402	hypoactivity	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0003891	increased allantois apoptosis	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0003891	increased allantois apoptosis	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0006042	increased apoptosis	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0006042	increased apoptosis	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0001748	increased circulating adrenocorticotropin level	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0002269	muscular atrophy	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0001651	necrosis	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0002058	neonatal lethality	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0003123	paternal imprinting	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0001732	postnatal growth retardation	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0001698	reduced embryo size	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0001939	secondary sex reversal	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0002768	small adrenal glands	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key
MP:0004259	small placenta	G6pdx	G6pdx^tm1Luz/G6pdx⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0004259	small placenta	G6pdx	G6pdx^tm1Luz/Y	involves: 129S1/Sv * C57BL/6J	color key
MP:0001147	small testis	Cyp11a1	Cyp11a1^tm1Bcc/Cyp11a1^tm1Bcc	involves: 129X1/SvJ * C57BL/6	color key