MGI MouseCyc MP annotations for PWY3DJ-35471

MGI MouseCyc experimental MP annotations for vitamin C biosynthesis

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for vitamin C biosynthesis

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005386	behavior/neurological phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005385	cardiovascular system phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005381	digestive/alimentary phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005380	embryogenesis phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005378	growth/size phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005397	hematopoietic system phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005376	homeostasis/metabolism phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005387	immune system phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005374	lethality-prenatal/perinatal	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005372	life span-post-weaning/aging	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005371	limbs/digits/tail phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005370	liver/biliary system phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005369	muscle phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0003631	nervous system phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005367	renal/urinary system phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005390	skeleton phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005393	skin/coat/nails phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2
MP:0005391	vision/eye phenotype	Akr1a4	Gulo	Rgn	Ugdh	Ugp2

Full set of annotations for vitamin C biosynthesis

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0003211	abnormal aorta elastic fiber morphology	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0002896	abnormal bone mineralization	Gulo	Gulo^sfx-2J/Gulo^sfx-2J	RB156Bnr/Ei rul-Gulo/J	color key
MP:0000130	abnormal cancellous bone morphology	Gulo	Gulo^sfx-2J/Gulo^sfx-2J	RB156Bnr/Ei rul-Gulo/J	color key
MP:0001685	abnormal endoderm development	Ugdh	Ugdh^lzme/Ugdh^lzme	C3Fe.B6-Ugdh	color key
MP:0000559	abnormal femur morphology	Gulo	Gulo^sfx-2J/Gulo^sfx-2J	RB156Bnr/Ei rul-Gulo/J	color key
MP:0001406	abnormal gait	Gulo	Gulo^sfx-2J/Gulo^sfx-2J	RB156Bnr/Ei rul-Gulo/J	color key
MP:0003055	abnormal long bone epiphyseal plate morphology	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0001680	abnormal mesoderm development	Ugdh	Ugdh^lzme/Ugdh^lzme	C3Fe.B6-Ugdh	color key
MP:0008396	abnormal osteoclast differentiation	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0002231	abnormal primitive streak morphology	Ugdh	Ugdh^lzme/Ugdh^lzme	involves: C3HeB/FeJ * C57BL/6J	color key
MP:0001325	abnormal retina morphology	Gulo	Gulo^sfx-2J/Gulo^sfx-2J	RB156Bnr/Ei rul-Gulo/J	color key
MP:0001533	abnormal skeleton physiology	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0006055	abnormal vascular endothelial cell morphology	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0005592	abnormal vascular smooth muscle morphology	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0000141	abnormal vertebral body morphology	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0005400	abnormal vitamin level	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0001577	anemia	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0001304	cataracts	Gulo	Gulo^sfx-2J/Gulo^sfx-2J	RB156Bnr/Ei rul-Gulo/J	color key
MP:0001265	decreased body size	Gulo	Gulo^sfx-2J/Gulo^sfx-2J	RB156Bnr/Ei rul-Gulo/J	color key
MP:0000063	decreased bone density	Gulo	Gulo^sfx-2J/Gulo^sfx-2J	RB156Bnr/Ei rul-Gulo/J	color key
MP:0000063	decreased bone density	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0000167	decreased chondrocyte cell number	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0000186	decreased circulating HDL cholesterol level	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0002966	decreased circulating alkaline phosphatase level	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0004701	decreased circulating insulin-like growth factor I level	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0000135	decreased cortical bone thickness	Gulo	Gulo^sfx-2J/Gulo^sfx-2J	RB156Bnr/Ei rul-Gulo/J	color key
MP:0000135	decreased cortical bone thickness	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0002875	decreased erythrocyte cell number	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0000208	decreased hematocrit	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0000208	decreased hematocrit	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0005562	decreased mean corpuscular hemoglobin	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0001511	disheveled coat	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0001730	embryonic growth arrest	Ugdh	Ugdh^lzme/Ugdh^lzme	involves: C3HeB/FeJ * C57BL/6J	color key
MP:0001730	embryonic growth arrest	Ugdh	Ugdh^lzme/Ugdh^lzme	C3Fe.B6-Ugdh	color key
MP:0003984	embryonic growth retardation	Ugdh	Ugdh^lzme/Ugdh^lzme	C3Fe.B6-Ugdh	color key
MP:0003068	enlarged kidney	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0000061	fragile skeleton	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0000465	gastrointestinal hemorrhage	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0001914	hemorrhage	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0000755	hindlimb paralysis	Gulo	Gulo^sfx-2J/Gulo^sfx-2J	RB156Bnr/Ei rul-Gulo/J	color key
MP:0001402	hypoactivity	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0000195	hypocalcemia	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0000198	hypophosphatemia	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0005238	increased brain size	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0005178	increased circulating cholesterol level	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0003887	increased hepatocyte apoptosis	Rgn	Rgn^tm1Aish/Rgn^tm1Aish	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0003070	increased vascular permeability	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0001732	postnatal growth retardation	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0008489	postnatal slow weight gain	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0002083	premature death	Gulo	Gulo^sfx-2J/Gulo^sfx-2J	RB156Bnr/Ei rul-Gulo/J	color key
MP:0002083	premature death	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key
MP:0002080	prenatal lethality	Ugdh	Ugdh^lzme/Ugdh^lzme	involves: C3HeB/FeJ * C57BL/6J	color key
MP:0002080	prenatal lethality	Ugdh	Ugdh^lzme/Ugdh^lzme	C3Fe.B6-Ugdh	color key
MP:0003116	rickets	Gulo	Gulo^sfx-2J/Gulo^sfx-2J	RB156Bnr/Ei rul-Gulo/J	color key
MP:0000692	small spleen	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0000706	small thymus	Gulo	Gulo^sfx/Gulo^sfx	BALB/cBy-Gulo/J	color key
MP:0001263	weight loss	Gulo	Gulo^tm1Mae/Gulo^tm1Mae	involves: 129 * C57BL/6	color key