MGI MouseCyc MP annotations for PWY3DJ-11281

MGI MouseCyc experimental MP annotations for sphingomyelin metabolism

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for sphingomyelin metabolism

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0005386	behavior/neurological phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0005384	cellular phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0005379	endocrine/exocrine gland phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0005378	growth/size phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0005397	hematopoietic system phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0005376	homeostasis/metabolism phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0005387	immune system phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0005372	life span-post-weaning/aging	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0005371	limbs/digits/tail phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0005370	liver/biliary system phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0003631	nervous system phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0002873	normal phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0005389	reproductive system phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0005388	respiratory system phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4
MP:0005390	skeleton phenotype	Enpp7	Sgms1	Sgms2	Smpd1	Smpd2	Smpd3	Smpd4

Full set of annotations for sphingomyelin metabolism

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0004163	abnormal adenohypophysis morphology	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0001739	abnormal adrenal gland secretion	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0001648	abnormal apoptosis	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0000849	abnormal cerebellum morphology	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0000788	abnormal cerebral cortex morphology	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0000820	abnormal choroid plexus morphology	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0000559	abnormal femur morphology	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0002187	abnormal fibula morphology	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0002462	abnormal granulocyte physiology	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0000716	abnormal immune system cell morphology	Smpd1	Smpd1^tm1Esc/Smpd1⁺	involves: 129S1/Sv * C57BL/6J	color key
MP:0002118	abnormal lipid homeostasis	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0002118	abnormal lipid homeostasis	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0003723	abnormal long bone morphology	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0006362	abnormal male germ cell morphology	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0000897	abnormal midbrain morphology	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0001131	abnormal ovarian follicle morphology	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0001126	abnormal ovary morphology	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0000633	abnormal pituitary gland morphology	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0002270	abnormal respiratory alveoli morphology	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001156	abnormal spermatogenesis	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0001146	abnormal testis morphology	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0000558	abnormal tibia morphology	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0002675	asthenozoospermia	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0001393	ataxia	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0001393	ataxia	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001255	decreased body height	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0001262	decreased body weight	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0000774	decreased brain size	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0004701	decreased circulating insulin-like growth factor I level	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0008341	decreased corticotroph cell number	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0008335	decreased gonadotroph cell number	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0008329	decreased somatotroph cell number	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0008338	decreased thyrotroph cell number	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0005471	decreased thyroxine level	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0005473	decreased triiodothyronine level	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0003409	decreased width of hypertrophic chondrocyte zone	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0000060	delayed bone ossification	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0001938	delayed sexual maturation	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0002427	disproportionate dwarf	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0000599	enlarged liver	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0000691	enlarged spleen	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0004201	fetal growth retardation	Smpd3	Smpd3^tm1Wst/Smpd3^tm1Wst	involves: 129S1/Sv	color key
MP:0002183	gliosis	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001505	hunched posture	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0001405	impaired coordination	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0003666	impaired sperm capacitation	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0001556	increased circulating HDL cholesterol level	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0004778	increased foam cell number	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0004778	increased foam cell number	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0002412	increased susceptibility to bacterial infection	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0005202	lethargy	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0002169	no abnormal phenotype detected	Smpd2	Smpd2^tm1Wst/Smpd2^tm1Wst	involves: 129S1/Sv * C57BL/6	color key
MP:0000876	Purkinje cell degeneration	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002083	premature death	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0000876	Purkinje cell degeneration	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0002083	premature death	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0001954	respiratory distress	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0005578	teratozoospermia	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0000745	tremors	Smpd1	Smpd1^tm1Esc/Smpd1^tm1Esc	involves: 129S1/Sv * C57BL/6J	color key
MP:0000745	tremors	Smpd1	Smpd1^tm1Wst/Smpd1^tm1Wst	involves: 129P2/OlaHsd * C57BL/6	color key