MGI MouseCyc MP annotations for PWY0-166

MGI MouseCyc experimental MP annotations for de novo biosynthesis of pyrimidine deoxyribonucleotides

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for de novo biosynthesis of pyrimidine deoxyribonucleotides

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005385	cardiovascular system phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005384	cellular phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005381	digestive/alimentary phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005379	endocrine/exocrine gland phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005378	growth/size phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005397	hematopoietic system phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005376	homeostasis/metabolism phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005387	immune system phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005373	lethality-postnatal	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005372	life span-post-weaning/aging	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005370	liver/biliary system phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005369	muscle phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0003631	nervous system phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005395	other phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005367	renal/urinary system phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0005389	reproductive system phenotype	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms
MP:0002006	tumorigenesis	Dtymk	Dut	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Rp2h	Rrm1	Rrm1-rs13	Rrm2	Rrm2b	Tyms

Full set of annotations for de novo biosynthesis of pyrimidine deoxyribonucleotides

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0001648	abnormal apoptosis	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0002191	abnormal artery morphology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0005265	abnormal blood urea nitrogen level	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0000662	abnormal branching of the mammary ductal tree	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	129-Nme1	color key
MP:0005328	abnormal circulating creatinine level	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0000199	abnormal circulating serum albumin level	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0002184	abnormal innervation	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	involves: 129/Sv * C57BL/6	color key
MP:0002136	abnormal kidney physiology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0001882	abnormal lactation	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	129-Nme1	color key
MP:0000598	abnormal liver morphology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0005232	abnormal mesenteric lymph node morphology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0000613	abnormal salivary gland morphology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0002651	abnormal sciatic nerve	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0000759	abnormal skeletal muscle morphology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0000703	abnormal thymus morphology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0003141	cardiac fibrosis	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0001262	decreased body weight	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	involves: 129/Sv * C57BL/6	color key
MP:0001262	decreased body weight	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	B6.129-Nme1	color key
MP:0001262	decreased body weight	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	129-Nme1	color key
MP:0005517	decreased liver regeneration	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	involves: 129/Sv * C57BL/6	color key
MP:0008479	decreased spleen white pulp amount	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0002705	dilated renal tubules	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0005264	glomerulosclerosis	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0003606	kidney failure	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0002022	lymphoma	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	involves: 129/Sv * C57BL/6	color key
MP:0003718	maternal effect	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	involves: 129/Sv * C57BL/6	color key
MP:0003718	maternal effect	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	B6.129-Nme1	color key
MP:0001732	postnatal growth retardation	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0002082	postnatal lethality	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	involves: 129/Sv * C57BL/6	color key
MP:0002082	postnatal lethality	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	B6.129-Nme1	color key
MP:0002082	postnatal lethality	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	129-Nme1	color key
MP:0002083	premature death	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0005160	proteinuria	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key