MGI MouseCyc MP annotations for PWY0-1296

MGI MouseCyc experimental MP annotations for degradation of purine ribonucleosides

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for degradation of purine ribonucleosides

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0005386	behavior/neurological phenotype	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0005384	cellular phenotype	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0005378	growth/size phenotype	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0005397	hematopoietic system phenotype	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0005376	homeostasis/metabolism phenotype	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0005387	immune system phenotype	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0005373	lethality-postnatal	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0005374	lethality-prenatal/perinatal	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0005370	liver/biliary system phenotype	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0003631	nervous system phenotype	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0002873	normal phenotype	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0005367	renal/urinary system phenotype	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0005389	reproductive system phenotype	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0005388	respiratory system phenotype	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2
MP:0005390	skeleton phenotype	Ada	Adad1	Adad2	Adarb1	Pnp1	Pnp2

Full set of annotations for degradation of purine ribonucleosides

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0002885	abnormal AMPA-mediated synaptic currents	Adarb1	Adarb1^tm1Phs/Adarb1^tm1Phs	Not Specified	color key
MP:0002376	abnormal dendritic cell physiology	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd	color key
MP:0005319	abnormal enzyme/ coenzyme level	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0005584	abnormal enzyme/coenzyme activity	Pnp1	Pnp1^f/Pnp1^f	involves: C3H/HeHa * C57BL/6J	color key
MP:0005584	abnormal enzyme/coenzyme activity	Pnp1	Pnp1^e/Pnp1^e	involves: C3H/HeHa * C57BL/6J	color key
MP:0005584	abnormal enzyme/coenzyme activity	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0005584	abnormal enzyme/coenzyme activity	Pnp1	Pnp1^h/Pnp1^h	involves: C3H/HeHa * C57BL/6J	color key
MP:0005584	abnormal enzyme/coenzyme activity	Pnp1	Pnp1ⁱ/Pnp1ⁱ	involves: C3H/HeHa * C57BL/6J	color key
MP:0000607	abnormal hepatocyte morphology	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0005555	abnormal kidney excretion	Pnp1	Pnp1^f/Pnp1^f	involves: C3H/HeHa * C57BL/6J	color key
MP:0005555	abnormal kidney excretion	Pnp1	Pnp1^e/Pnp1^e	involves: C3H/HeHa * C57BL/6J	color key
MP:0000217	abnormal leukocyte cell number	Pnp1	Pnp1^f/Pnp1^f	C57BL/6J-Pnp1	color key
MP:0000217	abnormal leukocyte cell number	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0000598	abnormal liver morphology	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0003806	abnormal nucleotide metabolism	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0001379	abnormal penile erection function	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6 * FVB/N	color key
MP:0005325	abnormal renal glomerulus morphology	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0002703	abnormal renal tubule morphology	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0002270	abnormal respiratory alveoli morphology	Ada	Ada^tm1Vlr/Ada^tm1Vlr	either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N)	color key
MP:0000150	abnormal rib morphology	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0002356	abnormal spleen red pulp morphology	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0002365	abnormal thymus cellularity	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0002365	abnormal thymus cellularity	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0002365	abnormal thymus cellularity	Pnp1	Pnp1^e/Pnp1^e	C57BL/6J-Pnp1	color key
MP:0002365	abnormal thymus cellularity	Pnp1	Pnp1^f/Pnp1^f	C57BL/6J-Pnp1	color key
MP:0002367	abnormal thymus lobule morphology	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0001577	anemia	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0002675	asthenozoospermia	Adad1	Adad1^tm1Reb/Adad1^tm1Reb	129X1/SvJ-Tenr	color key
MP:0001177	atelectasis	Ada	Ada^tm1Vlr/Ada^tm1Vlr	either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N)	color key
MP:0001575	cyanosis	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0001575	cyanosis	Ada	Ada^tm1Vlr/Ada^tm1Vlr	either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N)	color key
MP:0008079	decreased CD8-positive T cell number	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0001262	decreased body weight	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0008079	decreased CD8-positive T cell number	Pnp1	Pnp1^f/Pnp1^f	C57BL/6J-Pnp1	color key
MP:0005018	decreased T cell number	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0005092	decreased double-positive T cell number	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0005092	decreased double-positive T cell number	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0005092	decreased double-positive T cell number	Pnp1	Pnp1^f/Pnp1^f	C57BL/6J-Pnp1	color key
MP:0000606	decreased hepatocyte number	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0002460	decreased immunoglobulin level	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0000221	decreased leukocyte cell number	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0006207	embryonic lethality during organogenesis	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6J	color key
MP:0000240	extramedullary hematopoiesis	Ada	Ada^tm1Vlr/Ada^tm1Vlr	either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N)	color key
MP:0001654	hepatic necrosis	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0001654	hepatic necrosis	Ada	Ada^tm1Vlr/Ada^tm1Vlr	either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N)	color key
MP:0005419	hypoalbuminemia	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0005417	hypoproteinemia	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0000242	impaired fertilization	Adad1	Adad1^tm1Reb/Adad1^tm1Reb	129X1/SvJ-Tenr	color key
MP:0008126	increased dendritic cell number	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd	color key
MP:0005090	increased double-negative T cell number	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0005090	increased double-negative T cell number	Pnp1	Pnp1^f/Pnp1^f	involves: C3H/HeHa * C57BL/6J	color key
MP:0005090	increased double-negative T cell number	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0005011	increased eosinophil cell number	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0000322	increased granulocyte number	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0005425	increased macrophage cell number	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0005415	intrahepatic cholestasis	Ada	Ada^tm1Vlr/Ada^tm1Vlr	either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N)	color key
MP:0001861	lung inflammation	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0001925	male infertility	Adad1	Adad1^tm1Reb/Adad1^tm1Reb	involves: 129X1/SvJ * C57BL/6	color key
MP:0001925	male infertility	Adad1	Adad1^tm1Reb/Adad1^tm1Reb	129X1/SvJ-Tenr	color key
MP:0001651	necrosis	Ada	Ada^tm1Vlr/Ada^tm1Vlr	either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N)	color key
MP:0002058	neonatal lethality	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0002058	neonatal lethality	Ada	Ada^tm1Vlr/Ada^tm1Vlr	either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N)	color key
MP:0002169	no abnormal phenotype detected	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLFSADA)2465Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6 * FVB/N	color key
MP:0002169	no abnormal phenotype detected	Adarb1	Adarb1^tm1.1Eme/Adarb1^tm1.1Eme	involves: 129S6/SvEvTac * C57BL/6J	color key
MP:0002169	no abnormal phenotype detected	Adarb1	Adarb1^tm1Phs/Adarb1^tm1Phs,Gria2^tm1.1Phs/Gria2^tm1.1Phs	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0002687	oligozoospermia	Adad1	Adad1^tm1Reb/Adad1^tm1Reb	129X1/SvJ-Tenr	color key
MP:0002082	postnatal lethality	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0002082	postnatal lethality	Adarb1	Adarb1^tm1Phs/Adarb1^tm1Phs,Gria2^tm1.1Phs/Gria2⁺	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0002082	postnatal lethality	Adarb1	Adarb1^tm1Phs/Adarb1^tm1Phs	Not Specified	color key
MP:0002080	prenatal lethality	Pnp1	Pnp1^g/Pnp1^g	involves: C57BL/6 * DBA/2J	color key
MP:0003415	priapism	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6 * FVB/N	color key
MP:0002064	seizures	Adarb1	Adarb1^tm1Phs/Adarb1^tm1Phs	Not Specified	color key
MP:0000601	small liver	Ada	Ada^tm1Mw/Ada^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0000692	small spleen	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0000706	small thymus	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0000694	spleen hypoplasia	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0005426	tachypnea	Ada	Ada^tm1Mw/Ada^tm1Mw,Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0005578	teratozoospermia	Adad1	Adad1^tm1Reb/Adad1^tm1Reb	129X1/SvJ-Tenr	color key