MGI MouseCyc MP annotations for PWY-5920

MGI MouseCyc experimental MP annotations for heme biosynthesis II

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for heme biosynthesis II

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005375	adipose tissue phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005386	behavior/neurological phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005382	craniofacial phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005380	embryogenesis phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005378	growth/size phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005397	hematopoietic system phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005376	homeostasis/metabolism phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005387	immune system phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005374	lethality-prenatal/perinatal	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005370	liver/biliary system phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0002873	normal phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005367	renal/urinary system phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005389	reproductive system phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005390	skeleton phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros
MP:0005393	skin/coat/nails phenotype	Alad	Alas1	Alas2	Cpox	Fech	Hmbs	Ppox	Urod	Uros

Full set of annotations for heme biosynthesis II

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0001570	abnormal circulating enzyme level	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0005416	abnormal circulating protein level	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0001243	abnormal dermal layer morphology	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6 * SKH1	color key
MP:0004229	abnormal embryonic erythropoiesis	Alas2	Alas2^tm1Mym/Y	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0003396	abnormal embryonic hematopoiesis	Alas2	Alas2^tm1Mym/Y	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0005584	abnormal enzyme/coenzyme activity	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0005584	abnormal enzyme/coenzyme activity	Uros	Uros^tm3Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0003657	abnormal erythrocyte lysis	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0002447	abnormal erythrocyte morphology	Fech	Fech^m1Pas/Fech^m1Pas,hem6/hem6⁺	involves: 129 * BALB/c * C57BL/6	color key
MP:0002447	abnormal erythrocyte morphology	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0003656	abnormal erythrocyte physiology	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0000245	abnormal erythropoiesis	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0000245	abnormal erythropoiesis	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0001770	abnormal iron level	Alas2	Alas2^tm1Mym/Y	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0005325	abnormal renal glomerulus morphology	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0002703	abnormal renal tubule morphology	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0005508	abnormal skeleton morphology	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0001250	abnormal superficial dermis morphology	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6 * SKH1	color key
MP:0002100	abnormal tooth morphology	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0003619	abnormal urine color	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0001874	acanthosis	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6 * SKH1	color key
MP:0001577	anemia	Alas2	Alas2^tm1Mym/Y	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002642	anisocytosis	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0002642	anisocytosis	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0005454	decreased adipose tissue amount	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0000237	decreased blood cell number	Alas2	Alas2^tm1Mym/Y	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002875	decreased erythrocyte cell number	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0000208	decreased hematocrit	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0002874	decreased hemoglobin content	Fech	Fech^m1Pas/Fech^m1Pas,hem6/hem6	involves: 129 * BALB/c * C57BL/6	color key
MP:0002874	decreased hemoglobin content	Fech	Fech^m1Pas/Fech^m1Pas,hem6/hem6⁺	involves: 129 * BALB/c * C57BL/6	color key
MP:0002874	decreased hemoglobin content	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0001270	distended abdomen	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0006204	embryonic lethality before implantation	Uros	Uros^tm2Cged/Uros^tm2Cged	involves: 129S2/SvPas	color key
MP:0006205	embryonic lethality before somite formation	Urod	Urod^tm1Kush/Urod^tm1Kush	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0006206	embryonic lethality before turning of embryo	Fech	Fech^tm1Dab/Fech^tm1Dab	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0006207	embryonic lethality during organogenesis	Alas2	Alas2^tm1Mym/Y	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0000599	enlarged liver	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0000691	enlarged spleen	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0000691	enlarged spleen	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0000061	fragile skeleton	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0001585	hemolytic anemia	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0001585	hemolytic anemia	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0002628	hepatic steatosis	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0001402	hypoactivity	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0008387	hypochromic anemia	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0008388	hypochromic microcytic anemia	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0000321	increased bone marrow cell number	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0002968	increased circulating alkaline phosphatase level	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0005344	increased circulating bilirubin level	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0008807	increased liver iron level	Urod	Hfe^tm2Nca/Hfe^tm2Nca,Urod^tm1Kush/Urod⁺	involves: C57BL/6J	color key
MP:0002981	increased liver weight	Fech	Fech^m1Pas/Fech^m1Pas,hem6/hem6⁺	involves: 129 * BALB/c * C57BL/6	color key
MP:0002981	increased liver weight	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0004147	increased porphyrin level	Fech	Fech^m1Pas/Fech^m1Pas,hem6/hem6	involves: 129 * BALB/c * C57BL/6	color key
MP:0004147	increased porphyrin level	Fech	Fech^m1Pas/Fech^m1Pas,hem6/hem6⁺	involves: 129 * BALB/c * C57BL/6	color key
MP:0004147	increased porphyrin level	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0004147	increased porphyrin level	Urod	Hfe^tm2Nca/Hfe^tm2Nca,Urod^tm1Kush/Urod⁺	involves: C57BL/6J	color key
MP:0004147	increased porphyrin level	Uros	Uros^tm1Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0004147	increased porphyrin level	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0004147	increased porphyrin level	Uros	Uros^tm3Rjde/Uros^tm4Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0004147	increased porphyrin level	Uros	Uros^tm3Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6 * SKH1	color key
MP:0004147	increased porphyrin level	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6 * SKH1	color key
MP:0004147	increased porphyrin level	Uros	Uros^tm3Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0008809	increased spleen iron level	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0008476	increased spleen red pulp amount	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0004952	increased spleen weight	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0000611	jaundice	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0001246	mixed cellular infiltration to dermis	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6 * SKH1	color key
MP:0002169	no abnormal phenotype detected	Urod	Urod^tm1Kush/Urod⁺	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0003717	pallor	Alas2	Alas2^tm1Mym/Y	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002643	poikilocytosis	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0005097	polychromatophilia	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0005654	porphyria	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0002080	prenatal lethality	Uros	Uros^tm4Rjde/Uros^tm4Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0002080	prenatal lethality	Uros	Uros^tm2Rjde/Uros^tm2Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0002080	prenatal lethality	Uros	Uros^tm1Rjde/Uros^tm1Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0001921	reduced fertility	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0004200	reduced fetal size	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0002640	reticulocytosis	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0002640	reticulocytosis	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0001202	skin photosensitivity	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0001202	skin photosensitivity	Fech	Fech^tm1Dab/Fech⁺	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001202	skin photosensitivity	Uros	Uros^tm1Cged/Uros^tm1Cged	involves: 129S2/SvPas	color key
MP:0001202	skin photosensitivity	Uros	Uros^tm3Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6 * SKH1	color key
MP:0001202	skin photosensitivity	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6 * SKH1	color key
MP:0001200	thick skin	Uros	Uros^tm2Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6 * SKH1	color key
MP:0001219	thickened epidermis	Uros	Uros^tm3Rjde/Uros^tm3Rjde	involves: 129S6/SvEvTac * C57BL/6 * SKH1	color key