MGI MouseCyc MP annotations for PWY-5910

MGI MouseCyc experimental MP annotations for superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
MP:0005384	cellular phenotype	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
MP:0005380	embryogenesis phenotype	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
MP:0005397	hematopoietic system phenotype	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
MP:0005376	homeostasis/metabolism phenotype	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
MP:0005387	immune system phenotype	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
MP:0005374	lethality-prenatal/perinatal	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
MP:0002873	normal phenotype	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk
MP:0002006	tumorigenesis	Acat1	Acat2	Fdps	Fntb	Ggps1	Hmgcr	Hmgcs1	Hmgcs2	Idi1	Idi2	Mvd	Mvk	Nudt12	Pmvk

Full set of annotations for superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0001675	abnormal ectoderm development	Fntb	Fntb^tm1.1Bbd/Fntb^tm1.1Bbd	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001545	abnormal hematopoietic system physiology	Fntb	Fntb^tm1Bbd/Fntb^tm1Bbd,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key
MP:0001545	abnormal hematopoietic system physiology	Fntb	Fntb^tm1Bbd/Fntb^tm1.1Bbd,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key
MP:0004966	abnormal inner cell mass proliferation	Fntb	Fntb^tm1.1Bbd/Fntb^tm1.1Bbd	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002225	abnormal spleen cellularity	Fntb	Fntb^tm1Bbd/Fntb^tm1.1Bbd,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key
MP:0002225	abnormal spleen cellularity	Fntb	Fntb^tm1Bbd/Fntb^tm1Bbd,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key
MP:0000352	decreased cell proliferation	Fntb	Fntb^tm1Bbd/Fntb^tm1.1Bbd,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key
MP:0000352	decreased cell proliferation	Fntb	Fntb^tm1Bbd/Fntb^tm1Bbd,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key
MP:0004502	decreased incidence of chemically-induced tumors	Fntb	Fntb^tm1Bbd/Fntb^tm1Bbd,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key
MP:0004502	decreased incidence of chemically-induced tumors	Fntb	Fntb^tm1Bbd/Fntb^tm1.1Bbd,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key
MP:0002908	delayed wound healing	Fntb	Fntb^tm1Bbd/Fntb^tm1.1Bbd,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key
MP:0002908	delayed wound healing	Fntb	Fntb^tm1Bbd/Fntb^tm1Bbd,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key
MP:0006206	embryonic lethality before turning of embryo	Hmgcr	Hmgcr^tm1Ishi/Hmgcr^tm1Ishi	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0006207	embryonic lethality during organogenesis	Fntb	Fntb^tm1.1Bbd/Fntb^tm1.1Bbd	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002027	lung adenocarcinoma	Fntb	Fntb^tm1Bbd/Fntb^tm1Bbd,Kras^tm1Bbd/Kras⁺,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key
MP:0002048	lung adenoma	Fntb	Fntb^tm1Bbd/Fntb^tm1Bbd,Kras^tm1Bbd/Kras⁺,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key
MP:0002169	no abnormal phenotype detected	Hmgcr	Hmgcr^tm1Ishi/Hmgcr⁺	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0000692	small spleen	Fntb	Fntb^tm1Bbd/Fntb^tm1.1Bbd,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key
MP:0000692	small spleen	Fntb	Fntb^tm1Bbd/Fntb^tm1Bbd,Tg(CMV-cre/ESR1)1Ipc/Tg(CMV-cre/ESR1)1Ipc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	color key