MGI MouseCyc MP annotations for PWY-5874

MGI MouseCyc experimental MP annotations for heme degradation

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for heme degradation

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Blvra	Blvrb	Hmox1	Hmox2
MP:0005386	behavior/neurological phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005385	cardiovascular system phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005384	cellular phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005381	digestive/alimentary phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005379	endocrine/exocrine gland phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005378	growth/size phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005397	hematopoietic system phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005376	homeostasis/metabolism phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005387	immune system phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005373	lethality-postnatal	Blvra	Blvrb	Hmox1	Hmox2
MP:0005374	lethality-prenatal/perinatal	Blvra	Blvrb	Hmox1	Hmox2
MP:0005372	life span-post-weaning/aging	Blvra	Blvrb	Hmox1	Hmox2
MP:0005370	liver/biliary system phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005369	muscle phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0003631	nervous system phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005367	renal/urinary system phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005389	reproductive system phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005388	respiratory system phenotype	Blvra	Blvrb	Hmox1	Hmox2
MP:0005392	touch/vibrissae phenotype	Blvra	Blvrb	Hmox1	Hmox2

Full set of annotations for heme degradation

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0002191	abnormal artery morphology	Hmox1	Hmox1^tm1Mlee/Hmox1^tm1Mlee	B6.129S2-Hmox1	color key
MP:0002972	abnormal cardiac muscle contractility	Hmox1	Hmox1^tm1Ysh/Hmox1⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0001544	abnormal cardiovascular system physiology	Hmox1	Hmox1^tm1Ysh/Hmox1⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0005416	abnormal circulating protein level	Hmox2	Hmox2^tm1Poss/Hmox2^tm1Poss	B6.129S2-Hmox2	color key
MP:0001657	abnormal induced morbidity/mortality	Hmox2	Hmox2^tm1Poss/Hmox2^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0006001	abnormal intestinal transit time	Hmox2	Hmox2^tm1Poss/Hmox2^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0005637	abnormal iron homeostasis	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0001770	abnormal iron level	Hmox2	Hmox2^tm1Poss/Hmox2^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0000217	abnormal leukocyte cell number	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0003919	abnormal lymph node cellularity	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0003477	abnormal nerve fiber response	Hmox2	Hmox2^tm1Poss/Hmox2^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0002736	abnormal nociception after inflammation	Hmox2	Hmox2^tm1Poss/Hmox2^tm1Poss	B6.129S2-Hmox2	color key
MP:0002726	abnormal pulmonary vein morphology	Hmox2	Hmox2^tm1Poss/Hmox2^tm1Poss	B6.129S2-Hmox2	color key
MP:0001943	abnormal respiration	Hmox2	Hmox2^tm1Poss/Hmox2^tm1Poss	B6.129S2-Hmox2	color key
MP:0002133	abnormal respiratory system physiology	Hmox2	Hmox2^tm1Poss/Hmox2^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0002225	abnormal spleen cellularity	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0005595	abnormal vascular smooth muscle physiology	Hmox1	Hmox1^tm1Mlee/Hmox1^tm1Mlee	B6.129S2-Hmox1	color key
MP:0002309	abnormal vital capacity	Hmox2	Hmox2^tm1Poss/Hmox2^tm1Poss	B6.129S2-Hmox2	color key
MP:0000343	altered response to myocardial infarction	Hmox1	Hmox1^tm1Mlee/Hmox1^tm1Mlee	involves: 129S2/SvPas * BALB/c	color key
MP:0002642	anisocytosis	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0005150	cachexia	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0003141	cardiac fibrosis	Hmox1	Hmox1^tm1Mlee/Hmox1^tm1Mlee	involves: 129S2/SvPas * BALB/c	color key
MP:0002499	chronic inflammation	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0001265	decreased body size	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0005574	decreased breathing frequency	Hmox2	Hmox2^tm1Poss/Hmox2^tm1Poss	B6.129S2-Hmox2	color key
MP:0002875	decreased erythrocyte cell number	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0000208	decreased hematocrit	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0002874	decreased hemoglobin content	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0002591	decreased mean corpuscular volume	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0002754	dilated right ventricle	Hmox1	Hmox1^tm1Mlee/Hmox1^tm1Mlee	involves: 129S2/SvPas * BALB/c	color key
MP:0000702	enlarged lymph nodes	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0000691	enlarged spleen	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0000240	extramedullary hematopoiesis	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0002743	glomerulonephritis	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0005264	glomerulosclerosis	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0001402	hypoactivity	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0004151	hypoferremia	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0005039	hypoxia	Hmox2	Hmox2^tm1Poss/Hmox2^tm1Poss	B6.129S2-Hmox2	color key
MP:0005565	increased blood urea nitrogen level	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0003222	increased cardiomyocyte apoptosis	Hmox1	Hmox1^tm1Mlee/Hmox1^tm1Mlee	involves: 129S2/SvPas * BALB/c	color key
MP:0003037	increased infarction size	Hmox1	Hmox1^tm1Ysh/Hmox1⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0004153	increased renal tubule apoptosis	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0003913	increased right ventricle weight	Hmox1	Hmox1^tm1Mlee/Hmox1^tm1Mlee	involves: 129S2/SvPas * BALB/c	color key
MP:0001924	infertility	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0003606	kidney failure	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0003333	liver fibrosis	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0001860	liver inflammation	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0001861	lung inflammation	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0002810	microcytic anemia	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0006085	myocardial necrosis	Hmox1	Hmox1^tm1Ysh/Hmox1⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0006085	myocardial necrosis	Hmox1	Hmox1^tm1Mlee/Hmox1^tm1Mlee	involves: 129S2/SvPas * BALB/c	color key
MP:0003674	oxidative stress	Hmox1	Hmox1^tm1Mlee/Hmox1^tm1Mlee	involves: 129S2/SvPas * BALB/c	color key
MP:0003674	oxidative stress	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0002081	perinatal lethality	Hmox1	Hmox1^tm1Mlee/Hmox1^tm1Mlee	involves: 129S2/SvPas * BALB/c	color key
MP:0001443	poor grooming	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0002082	postnatal lethality	Hmox1	Hmox1^tm1Mlee/Hmox1^tm1Mlee	involves: 129S2/SvPas * BALB/c	color key
MP:0002082	postnatal lethality	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0002083	premature death	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0002080	prenatal lethality	Hmox1	Hmox1^tm1Ysh/Hmox1^tm1Ysh	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0004154	renal tubular necrosis	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0001147	small testis	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0000693	spleen hyperplasia	Hmox1	Hmox1^tm1Poss/Hmox1^tm1Poss	involves: 129S2/SvPas * C57BL/6	color key
MP:0005048	thrombosis	Hmox1	Hmox1^tm1Mlee/Hmox1^tm1Mlee	involves: 129S2/SvPas * BALB/c	color key