MGI MouseCyc MP annotations for PWY-4984

MGI MouseCyc experimental MP annotations for urea cycle

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for urea cycle

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Arg1	Arg2	Asl	Ass1	Cps1	Otc
MP:0005386	behavior/neurological phenotype	Arg1	Arg2	Asl	Ass1	Cps1	Otc
MP:0005378	growth/size phenotype	Arg1	Arg2	Asl	Ass1	Cps1	Otc
MP:0005397	hematopoietic system phenotype	Arg1	Arg2	Asl	Ass1	Cps1	Otc
MP:0005376	homeostasis/metabolism phenotype	Arg1	Arg2	Asl	Ass1	Cps1	Otc
MP:0005387	immune system phenotype	Arg1	Arg2	Asl	Ass1	Cps1	Otc
MP:0005373	lethality-postnatal	Arg1	Arg2	Asl	Ass1	Cps1	Otc
MP:0005374	lethality-prenatal/perinatal	Arg1	Arg2	Asl	Ass1	Cps1	Otc
MP:0005372	life span-post-weaning/aging	Arg1	Arg2	Asl	Ass1	Cps1	Otc
MP:0005370	liver/biliary system phenotype	Arg1	Arg2	Asl	Ass1	Cps1	Otc
MP:0005393	skin/coat/nails phenotype	Arg1	Arg2	Asl	Ass1	Cps1	Otc

Full set of annotations for urea cycle

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0005010	abnormal CD8-positive T cell morphology	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005311	abnormal circulating amino acid level	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0005311	abnormal circulating amino acid level	Arg2	Arg2^tm1Weo/Arg2⁺	involves: C57BL/6J	color key
MP:0005311	abnormal circulating amino acid level	Arg2	Arg2^tm1Weo/Arg2^tm1Weo	involves: C57BL/6J	color key
MP:0005311	abnormal circulating amino acid level	Asl	Asl^tm1Wjc/Asl^tm1Wjc	involves: 129S7/SvEvBrd	color key
MP:0005311	abnormal circulating amino acid level	Ass1	Ass1^tm1Bay/Ass1^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0005311	abnormal circulating amino acid level	Ass1	Ass1^tm1Bay/Ass1⁺	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0003009	abnormal cytokine secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005449	abnormal food intake	Asl	Asl^tm1Wjc/Asl^tm1Wjc	involves: 129S7/SvEvBrd	color key
MP:0002073	abnormal hair growth	Otc	Otc^spf/Otc^spf	Not Specified	color key
MP:0000607	abnormal hepatocyte morphology	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0001764	abnormal homeostasis	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0002722	abnormal immune system organ morphology	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002722	abnormal immune system organ morphology	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008751	abnormal interleukin level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000598	abnormal liver morphology	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0002138	abnormal liver/biliary system morphology	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0003313	abnormal locomotor activation	Asl	Asl^tm1Wjc/Asl^tm1Wjc	involves: 129S7/SvEvBrd	color key
MP:0002339	abnormal lymph node morphology	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002451	abnormal macrophage physiology	Arg1	Arg1^tm1Pmu/Arg1^tm1Pmu,Tg(Tek-cre)1Ywa/?	B6.Cg-Arg1 Tg(Tek-cre)1Ywa	color key
MP:0002451	abnormal macrophage physiology	Arg1	Arg1^tm1.1Pmu/Arg1^tm1.1Pmu	involves: C57BL/6	color key
MP:0003957	abnormal nitric oxide homeostasis	Arg1	Arg1^tm1.1Pmu/Arg1^tm1.1Pmu	involves: C57BL/6	color key
MP:0003957	abnormal nitric oxide homeostasis	Arg1	Arg1^tm1Pmu/Arg1^tm1Pmu,Tg(Tek-cre)1Ywa/?	B6.Cg-Arg1 Tg(Tek-cre)1Ywa	color key
MP:0008752	abnormal tumor necrosis factor level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001577	anemia	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0001577	anemia	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001265	decreased body size	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001262	decreased body weight	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0000208	decreased hematocrit	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000208	decreased hematocrit	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0002411	decreased susceptibility to bacterial infection	Arg1	Arg1^tm1Pmu/Arg1^tm1Pmu,Tg(Tek-cre)1Ywa/?	B6.Cg-Arg1 Tg(Tek-cre)1Ywa	color key
MP:0005026	decreased susceptibility to parasitic infection	Arg1	Arg1^tm1Pmu/Arg1^tm1Pmu,Lyz2^tm1(cre)Ifo/?	B6.Cg-Arg1 Lyz2	color key
MP:0000422	delayed hair appearance	Otc	Otc^spf/Otc⁺	Not Specified	color key
MP:0001194	dermatitis	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000599	enlarged liver	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0000702	enlarged lymph nodes	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0000702	enlarged lymph nodes	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000702	enlarged lymph nodes	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000691	enlarged spleen	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0000691	enlarged spleen	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008074	increased CD4-positive T cell number	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0005309	increased circulating ammonia level	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0002494	increased IgM level	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008074	increased CD4-positive T cell number	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005309	increased circulating ammonia level	Asl	Asl^tm1Wjc/Asl^tm1Wjc	involves: 129S7/SvEvBrd	color key
MP:0005309	increased circulating ammonia level	Ass1	Ass1^tm1Bay/Ass1^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002493	increased IgG level	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005309	increased circulating ammonia level	Cps1	Cps1^tm1Mw/Cps1^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0002493	increased IgG level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002494	increased IgM level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002461	increased immunoglobulin level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008699	increased interleukin-4 secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008705	increased interleukin-6 secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008097	increased plasma cell number	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008560	increased tumor necrosis factor secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002058	neonatal lethality	Ass1	Ass1^tm1Bay/Ass1^tm1Bay	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0000603	pale liver	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0000418	patchy hair	Otc	Otc^spf/Otc^spf	Not Specified	color key
MP:0000418	patchy hair	Otc	Otc^spf/Otc⁺	Not Specified	color key
MP:0002082	postnatal lethality	Arg1	Arg1^tm1.1Pmu/Arg1^tm1.1Pmu	involves: C57BL/6	color key
MP:0002082	postnatal lethality	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0002082	postnatal lethality	Asl	Asl^tm1Wjc/Asl^tm1Wjc	involves: 129S7/SvEvBrd	color key
MP:0002082	postnatal lethality	Cps1	Cps1^tm1Mw/Cps1^tm1Mw	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0002082	postnatal lethality	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0002083	premature death	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0002083	premature death	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000424	retarded hair growth	Otc	Otc^spf-ash/Otc⁺	Not Specified	color key
MP:0000424	retarded hair growth	Otc	Otc^spf-ash/Y	Not Specified	color key
MP:0000424	retarded hair growth	Otc	Otc^spf-ash/Otc^spf-ash	Not Specified	color key
MP:0001212	skin lesions	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0001211	wrinkled skin	Otc	Otc^spf-ash/Y	Not Specified	color key
MP:0001211	wrinkled skin	Otc	Otc^spf-ash/Otc^spf-ash	Not Specified	color key