MGI MouseCyc MP annotations for PWY-4981

MGI MouseCyc experimental MP annotations for proline biosynthesis V (from arginine)

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for proline biosynthesis V (from arginine)

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005386	behavior/neurological phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005378	growth/size phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005397	hematopoietic system phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005376	homeostasis/metabolism phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005387	immune system phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005373	lethality-postnatal	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005374	lethality-prenatal/perinatal	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005372	life span-post-weaning/aging	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0003631	nervous system phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0001186	pigmentation phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005367	renal/urinary system phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005393	skin/coat/nails phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005391	vision/eye phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl

Full set of annotations for proline biosynthesis V (from arginine)

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0005010	abnormal CD8-positive T cell morphology	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005311	abnormal circulating amino acid level	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0005311	abnormal circulating amino acid level	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0003009	abnormal cytokine secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005551	abnormal eye electrophysiology	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0002073	abnormal hair growth	Otc	Otc^spf/Otc^spf	Not Specified	color key
MP:0002722	abnormal immune system organ morphology	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002722	abnormal immune system organ morphology	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008751	abnormal interleukin level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002339	abnormal lymph node morphology	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001325	abnormal retina morphology	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0005201	abnormal retinal pigment epithelium morphology	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0005201	abnormal retinal pigment epithelium morphology	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0008752	abnormal tumor necrosis factor level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001757	abnormal urine chemistry	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0008585	absent photoreceptor outer segment	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0001577	anemia	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0001577	anemia	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001265	decreased body size	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001262	decreased body weight	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0000208	decreased hematocrit	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0000208	decreased hematocrit	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001327	decreased retinal photoreceptor cell number	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0000422	delayed hair appearance	Otc	Otc^spf/Otc⁺	Not Specified	color key
MP:0001194	dermatitis	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008581	disorganized photoreceptor inner segment	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0000702	enlarged lymph nodes	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000702	enlarged lymph nodes	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0000702	enlarged lymph nodes	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000691	enlarged spleen	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000691	enlarged spleen	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0005309	increased circulating ammonia level	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002494	increased IgM level	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008074	increased CD4-positive T cell number	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0002493	increased IgG level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008074	increased CD4-positive T cell number	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002494	increased IgM level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002493	increased IgG level	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002461	increased immunoglobulin level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008699	increased interleukin-4 secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008705	increased interleukin-6 secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008097	increased plasma cell number	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008560	increased tumor necrosis factor secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005202	lethargy	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002058	neonatal lethality	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0000418	patchy hair	Otc	Otc^spf/Otc^spf	Not Specified	color key
MP:0000418	patchy hair	Otc	Otc^spf/Otc⁺	Not Specified	color key
MP:0002082	postnatal lethality	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0002083	premature death	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0002083	premature death	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000424	retarded hair growth	Otc	Otc^spf-ash/Otc^spf-ash	Not Specified	color key
MP:0000424	retarded hair growth	Otc	Otc^spf-ash/Y	Not Specified	color key
MP:0000424	retarded hair growth	Otc	Otc^spf-ash/Otc⁺	Not Specified	color key
MP:0001326	retinal degeneration	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0001326	retinal degeneration	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0008582	short photoreceptor inner segment	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0008587	short photoreceptor outer segment	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001212	skin lesions	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0008515	thin retinal outer nuclear layer	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0001211	wrinkled skin	Otc	Otc^spf-ash/Otc^spf-ash	Not Specified	color key
MP:0001211	wrinkled skin	Otc	Otc^spf-ash/Y	Not Specified	color key