MGI MouseCyc MP annotations for PWY-4061

MGI MouseCyc experimental MP annotations for glutathione-mediated detoxification

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for glutathione-mediated detoxification

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0005386	behavior/neurological phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0005385	cardiovascular system phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0005384	cellular phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0005378	growth/size phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0005397	hematopoietic system phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0005376	homeostasis/metabolism phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0005387	immune system phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0005372	life span-post-weaning/aging	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0005370	liver/biliary system phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0003631	nervous system phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0002873	normal phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0005367	renal/urinary system phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0005389	reproductive system phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0005390	skeleton phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0005393	skin/coat/nails phenotype	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3
MP:0002006	tumorigenesis	Anpep	Folh1	Ggh	Gsta	Gsta1	Gsta2	Gsta3	Gsta4	Gstk1	Gstm1	Gstm2	Gstm3	Gstm4	Gstm5	Gstm6	Gstm7	Gsto1	Gsto2	Gstp1	Gstp2	Gstt1	Gstt2	Gstt3	Gstt4	Gstz1	Mgst1	Mgst3

Full set of annotations for glutathione-mediated detoxification

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0000260	abnormal angiogenesis	Folh1	Folh1^tm1Nle/Folh1^tm1Nle	involves: 129X1/SvJ * C57BL/6J	color key
MP:0000168	abnormal bone marrow development	Gsta4	Gsta4^tm1Pzim/Gsta4^tm1Pzim	involves: 129S1/Sv * 129S6/SvEvTac	color key
MP:0000607	abnormal hepatocyte morphology	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0001657	abnormal induced morbidity/mortality	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0001657	abnormal induced morbidity/mortality	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0002135	abnormal kidney morphology	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0000598	abnormal liver morphology	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0005266	abnormal metabolism	Gsta4	Gsta4^tm1Pzim/Gsta4^tm1Pzim	involves: 129S1/Sv * 129S6/SvEvTac	color key
MP:0004220	abnormal peripheral nervous system regeneration	Folh1	Folh1^tm1Nle/Folh1^tm1Nle	involves: 129X1/SvJ * C57BL/6J	color key
MP:0008875	abnormal pharmacokinetics of xenobiotics	Gstm1	Gstm1^tm1Kfuj/Gstm1^tm1Kfuj	involves: 129S1/Sv * C57BL/6J	color key
MP:0008875	abnormal pharmacokinetics of xenobiotics	Gstt1	Gstt1^tm1Kfuj/Gstt1^tm1Kfuj	involves: 129S1/Sv * C57BL/6J	color key
MP:0002703	abnormal renal tubule morphology	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0002651	abnormal sciatic nerve	Folh1	Folh1^tm1Nle/Folh1^tm1Nle	involves: 129X1/SvJ * C57BL/6J	color key
MP:0006055	abnormal vascular endothelial cell morphology	Folh1	Folh1^tm1Nle/Folh1^tm1Nle	involves: 129X1/SvJ * C57BL/6J	color key
MP:0000316	cellular necrosis	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0002499	chronic inflammation	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0005602	decreased angiogenesis	Folh1	Folh1^tm1Nle/Folh1^tm1Nle	involves: 129X1/SvJ * C57BL/6J	color key
MP:0001262	decreased body weight	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0006058	decreased cerebral infarction size	Folh1	Folh1^tm1Nle/Folh1^tm1Nle	involves: 129X1/SvJ * C57BL/6J	color key
MP:0000221	decreased leukocyte cell number	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0001935	decreased litter size	Gsta4	Gsta4^tm1Pzim/Gsta4^tm1Pzim	involves: 129S1/Sv * 129S6/SvEvTac	color key
MP:0004953	decreased spleen weight	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0006059	decreased susceptibility to ischemic brain injury	Folh1	Folh1^tm1Nle/Folh1^tm1Nle	involves: 129X1/SvJ * C57BL/6J	color key
MP:0002837	dystrophic cardiac calcinosis	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0001654	hepatic necrosis	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0001654	hepatic necrosis	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0002628	hepatic steatosis	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0002628	hepatic steatosis	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0005293	impaired glucose tolerance	Gsta4	Gsta4^{Gt(OST203280)Lex}/Gsta4^{Gt(OST203280)Lex}	involves: 129S5/SvEvBrd * C57BL/6J	color key
MP:0001363	increased anxiety-related response	Folh1	Folh1^tm1Nle/Folh1^tm1Nle	involves: 129X1/SvJ * C57BL/6J	color key
MP:0002842	increased blood pressure	Folh1	Folh1^tm1Nle/Folh1^tm1Nle	involves: 129X1/SvJ * C57BL/6J	color key
MP:0001260	increased body weight	Gstp1	Gstp1/Gstp2^tm1Wolf/Gstp1/Gstp2^tm1Wolf	involves: 129P2/OlaHsd * MF1	color key
MP:0001260	increased body weight	Gstp2	Gstp1/Gstp2^tm1Wolf/Gstp1/Gstp2^tm1Wolf	involves: 129P2/OlaHsd * MF1	color key
MP:0002941	increased circulating alanine transaminase level	Gsta4	Gsta4^tm1Pzim/Gsta4^tm1Pzim	involves: 129S1/Sv * 129S6/SvEvTac	color key
MP:0005343	increased circulating aspartate transaminase level	Gsta4	Gsta4^tm1Pzim/Gsta4^tm1Pzim	involves: 129S1/Sv * 129S6/SvEvTac	color key
MP:0003909	increased eating behavior	Folh1	Folh1^tm1Nle/Folh1^tm1Nle	involves: 129X1/SvJ * C57BL/6J	color key
MP:0003917	increased kidney weight	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0002981	increased liver weight	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0002412	increased susceptibility to bacterial infection	Gsta4	Gsta4^tm1Pzim/Gsta4^tm1Pzim	involves: 129S1/Sv * 129S6/SvEvTac	color key
MP:0002412	increased susceptibility to bacterial infection	Gsta4	Gsta4^tm1Pzim/Gsta4⁺	involves: 129S1/Sv * 129S6/SvEvTac	color key
MP:0002893	ketoaciduria	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0001860	liver inflammation	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0002169	no abnormal phenotype detected	Gstt2	Gstt2^{Gt(OST236003)Lex}/Gstt2^{Gt(OST236003)Lex}	involves: 129S5/SvEvBrd * C57BL/6J	color key
MP:0003674	oxidative stress	Gsta4	Gsta4^tm1Pzim/Gsta4^tm1Pzim	involves: 129S1/Sv * 129S6/SvEvTac	color key
MP:0003674	oxidative stress	Gstz1	Gstz1^tm1Jmfc/Gstz1^tm1Jmfc	129S4/SvJae-Gstz1	color key
MP:0003711	pathological neovascularization	Anpep	Anpep^tm1Sid/Anpep^tm1Sid	involves: 129S/SvEv * C57BL/6	color key
MP:0003711	pathological neovascularization	Anpep	Anpep^tm1Sid/Anpep⁺	involves: 129S/SvEv * C57BL/6	color key
MP:0002083	premature death	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key
MP:0002051	skin papilloma	Gstp1	Gstp1/Gstp2^tm1Wolf/Gstp1/Gstp2^tm1Wolf	involves: 129P2/OlaHsd * MF1	color key
MP:0002051	skin papilloma	Gstp2	Gstp1/Gstp2^tm1Wolf/Gstp1/Gstp2^tm1Wolf	involves: 129P2/OlaHsd * MF1	color key
MP:0001263	weight loss	Gstz1	Gstz1^tm1Pgb/Gstz1^tm1Pgb	BALB/c	color key