MGI MouseCyc MP annotations for PWY-4041

MGI MouseCyc experimental MP annotations for γ-glutamyl cycle

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for γ-glutamyl cycle

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005385	cardiovascular system phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005384	cellular phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005380	embryogenesis phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005379	endocrine/exocrine gland phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005378	growth/size phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005376	homeostasis/metabolism phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005387	immune system phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005374	lethality-prenatal/perinatal	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005372	life span-post-weaning/aging	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005371	limbs/digits/tail phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0003631	nervous system phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0002873	normal phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0001186	pigmentation phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005389	reproductive system phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005390	skeleton phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005393	skin/coat/nails phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
MP:0005391	vision/eye phenotype	Anpep	Gclc	Gclm	Ggct	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah

Full set of annotations for γ-glutamyl cycle

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0005332	abnormal amino acid level	Gclm	Gclm^tm1Tdal/Gclm^tm1Tdal	involves: 129 * C57BL/6J	color key
MP:0001259	abnormal body weight	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0005311	abnormal circulating amino acid level	Gclm	Gclm^tm1Tdal/Gclm^tm1Tdal	involves: 129 * C57BL/6J	color key
MP:0005311	abnormal circulating amino acid level	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002075	abnormal coat color	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk,Ggt5^tm1Mwl/Ggt5^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002075	abnormal coat color	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002075	abnormal coat color	Ggt5	Ggt1^tm1Zuk/Ggt1^tm1Zuk,Ggt5^tm1Mwl/Ggt5^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001672	abnormal embryogenesis/ development	Gclc	Gclc^tm1Mwl/Gclc^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0003890	abnormal embryonic-extraembryonic boundary morphology	Gclc	Gclc^tm1Mwl/Gclc^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0002078	abnormal glucose homeostasis	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001657	abnormal induced morbidity/mortality	Gclm	Gclm^tm1Tjka/Gclm^tm1Tjka	B6.129-Gclm	color key
MP:0001303	abnormal lens morphology	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0003662	abnormal long bone epiphyseal plate proliferative zone	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001130	abnormal ovarian folliculogenesis	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002089	abnormal postnatal growth/weight/body size	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0003936	abnormal reproductive system development	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001937	abnormal sexual maturation	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk,Ggt5^tm1Mwl/Ggt5^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001937	abnormal sexual maturation	Ggt5	Ggt1^tm1Zuk/Ggt1^tm1Zuk,Ggt5^tm1Mwl/Ggt5^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001134	absent corpus luteum	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001304	cataracts	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk,Ggt5^tm1Mwl/Ggt5^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001304	cataracts	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001304	cataracts	Ggt5	Ggt1^tm1Zuk/Ggt1^tm1Zuk,Ggt5^tm1Mwl/Ggt5^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0005087	decreased acute inflammation	Ggt5	Ggt5^tm1Mwl/Ggt5^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0004016	decreased bone mass	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0000352	decreased cell proliferation	Gclc	Gclc^tm1Mwl/Gclc^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0000371	diluted coat color	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002427	disproportionate dwarf	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001730	embryonic growth arrest	Gclc	Gclc^tm1Mwl/Gclc^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0003984	embryonic growth retardation	Gclc	Gclc^tm1Mwl/Gclc^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0006205	embryonic lethality before somite formation	Gclc	Gclc^tm1Mwl/Gclc^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0006206	embryonic lethality before turning of embryo	Gclc	Gclc^tm1Mwl/Gclc^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0001926	female infertility	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0006042	increased apoptosis	Gclc	Gclc^tm1Mwl/Gclc^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0008406	increased cellular sensitivity to hydrogen peroxide	Gclm	Gclm^tm1Tdal/Gclm^tm1Tdal	involves: 129 * C57BL/6J	color key
MP:0002941	increased circulating alanine transaminase level	Gclm	Gclm^tm1Tjka/Gclm^tm1Tjka	B6.129-Gclm	color key
MP:0008873	increased sensitivity to xenobiotics	Gclm	Gclm^tm1Tjka/Gclm^tm1Tjka	B6.129-Gclm	color key
MP:0008873	increased sensitivity to xenobiotics	Gclm	Gclm^tm1Tjka/Gclm⁺	B6.129-Gclm	color key
MP:0008235	increased susceptibility to neuronal excitotoxicity	Gclm	Gclm^tm1Tjka/Gclm^tm1Tjka	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0008235	increased susceptibility to neuronal excitotoxicity	Gclm	Gclm^tm1Tjka/Gclm^tm1Tjka	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0001925	male infertility	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002169	no abnormal phenotype detected	Gclc	Gclc^tm1Mwl/Gclc⁺	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0002687	oligozoospermia	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0003674	oxidative stress	Gclm	Gclm^tm1Tjka/Gclm^tm1Tjka	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0003674	oxidative stress	Gclm	Gclm^tm1Tjka/Gclm^tm1Tjka	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0003711	pathological neovascularization	Anpep	Anpep^tm1Sid/Anpep⁺	involves: 129S/SvEv * C57BL/6	color key
MP:0003711	pathological neovascularization	Anpep	Anpep^tm1Sid/Anpep^tm1Sid	involves: 129S/SvEv * C57BL/6	color key
MP:0001732	postnatal growth retardation	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk,Ggt5^tm1Mwl/Ggt5^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001732	postnatal growth retardation	Ggt5	Ggt1^tm1Zuk/Ggt1^tm1Zuk,Ggt5^tm1Mwl/Ggt5^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002083	premature death	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk,Ggt5^tm1Mwl/Ggt5^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002083	premature death	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002083	premature death	Ggt5	Ggt1^tm1Zuk/Ggt1^tm1Zuk,Ggt5^tm1Mwl/Ggt5^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001921	reduced fertility	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk,Ggt5^tm1Mwl/Ggt5^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001921	reduced fertility	Ggt5	Ggt1^tm1Zuk/Ggt1^tm1Zuk,Ggt5^tm1Mwl/Ggt5^tm1Mwl	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001147	small testis	Ggt1	Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J	color key