MGI MouseCyc MP annotations for PWY-3841

MGI MouseCyc experimental MP annotations for formylTHF biosynthesis II

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for formylTHF biosynthesis II

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
MP:0005380	embryogenesis phenotype	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
MP:0005378	growth/size phenotype	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
MP:0005376	homeostasis/metabolism phenotype	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
MP:0005374	lethality-prenatal/perinatal	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
MP:0005372	life span-post-weaning/aging	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
MP:0005371	limbs/digits/tail phenotype	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
MP:0005370	liver/biliary system phenotype	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
MP:0003631	nervous system phenotype	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
MP:0005389	reproductive system phenotype	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
MP:0005390	skeleton phenotype	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
MP:0005393	skin/coat/nails phenotype	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
MP:0005391	vision/eye phenotype	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms

Full set of annotations for formylTHF biosynthesis II

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0000886	abnormal cerebellar granule layer	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0005311	abnormal circulating amino acid level	Mtr	Mtr^tm1Lcb/Mtr⁺	involves: 129S/SvEv * Black Swiss	color key
MP:0005311	abnormal circulating amino acid level	Mtr	Mtr^tm1Lcb/Mtr⁺	129S/SvEv-Mtr	color key
MP:0005311	abnormal circulating amino acid level	Shmt1	Shmt1^tm1Stov/Shmt1⁺	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0005311	abnormal circulating amino acid level	Shmt1	Shmt1^tm1Stov/Shmt1^tm1Stov	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0006076	abnormal circulating homocysteine level	Mthfr	Mthfr^tm1Rzn/Mthfr⁺	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0006076	abnormal circulating homocysteine level	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0002118	abnormal lipid homeostasis	Mthfr	Mthfr^tm1Rzn/Mthfr⁺	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0002118	abnormal lipid homeostasis	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000609	abnormal liver physiology	Shmt1	Shmt1^tm1.1Stov/Shmt1⁺	129S/SvEv-Shmt1	color key
MP:0000609	abnormal liver physiology	Shmt1	Shmt1^tm1.1Stov/Shmt1^tm1.1Stov	involves: 129S7/SvEvBrd * BALB/cJ * C57BL/6	color key
MP:0000609	abnormal liver physiology	Shmt1	Shmt1^tm1.1Stov/Shmt1^tm1.1Stov	129S/SvEv-Shmt1	color key
MP:0001262	decreased body weight	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000884	delaminated Purkinje cell layer	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0001938	delayed sexual maturation	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0006207	embryonic lethality during organogenesis	Mtr	Mtr^tm1Lcb/Mtr^tm1Lcb	involves: 129S/SvEv * Black Swiss	color key
MP:0006207	embryonic lethality during organogenesis	Mtr	Mtr^tm1Lcb/Mtr^tm1Lcb	129S/SvEv-Mtr	color key
MP:0002750	exophthalmos	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000585	kinked tail	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000160	kyphosis	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0006208	lethality throughout fetal growth and development	Mthfd2	Mthfd2^tm1Rmk/Mthfd2^tm1Rmk	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000603	pale liver	Mthfd2	Mthfd2^tm1Rmk/Mthfd2^tm1Rmk	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0001732	postnatal growth retardation	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0002083	premature death	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0001698	reduced embryo size	Mthfd2	Mthfd2^tm1Rmk/Mthfd2^tm1Rmk	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0001921	reduced fertility	Mthfd1	Mthfd1^neut2/Mthfd1^neut2	involves: C57BL/6JAnl	color key
MP:0000592	short tail	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000852	small cerebellum	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000601	small liver	Mthfd2	Mthfd2^tm1Rmk/Mthfd2^tm1Rmk	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000416	sparse hair	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key