MGI MouseCyc MP annotations for MANGDPMET-PWY

MGI MouseCyc experimental MP annotations for GDP-mannose metabolism

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for GDP-mannose metabolism

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0005385	cardiovascular system phenotype	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0005384	cellular phenotype	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0005380	embryogenesis phenotype	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0005378	growth/size phenotype	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0005397	hematopoietic system phenotype	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0005376	homeostasis/metabolism phenotype	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0005387	immune system phenotype	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0005374	lethality-prenatal/perinatal	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0005370	liver/biliary system phenotype	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0002873	normal phenotype	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0005395	other phenotype	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0005367	renal/urinary system phenotype	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0005389	reproductive system phenotype	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2
MP:0005393	skin/coat/nails phenotype	Gmppa	Gmppb	Hk1	Hk2	Hk3	Hkdc1	Mpi	Pmm1	Pmm2

Full set of annotations for GDP-mannose metabolism

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0000260	abnormal angiogenesis	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0005621	abnormal cell physiology	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0000350	abnormal cell proliferation	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0002824	abnormal chorioallantoic fusion	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0002447	abnormal erythrocyte morphology	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0000245	abnormal erythropoiesis	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0008742	abnormal kidney iron level	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0001716	abnormal placenta labyrinth morphology	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0001711	abnormal placenta morphology	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0000689	abnormal spleen morphology	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0004255	abnormal spongiotrophoblast layer morphology	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0005031	abnormal trophoblast layer morphology	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0000259	abnormal vascular development	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0003229	abnormal vitelline vasculature	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0001719	absent vitelline blood vessels	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0001577	anemia	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0002642	anisocytosis	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0004073	caudal body truncation	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0001265	decreased body size	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0001262	decreased body weight	Hk2	Hk2^tm1Laak/Hk2⁺	involves: 129P2/OlaHsd * BALB/c * DBA/2	color key
MP:0002875	decreased erythrocyte cell number	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0000208	decreased hematocrit	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0002874	decreased hemoglobin content	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0005562	decreased mean corpuscular hemoglobin	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0004188	delayed embryo turning	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0003984	embryonic growth retardation	Hk2	Hk2^tm1Laak/Hk2^tm1Laak	involves: 129P2/OlaHsd * BALB/c * DBA/2	color key
MP:0003984	embryonic growth retardation	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0006204	embryonic lethality before implantation	Pmm2	Pmm2^tm1Cthl/Pmm2^tm1Cthl	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0006206	embryonic lethality before turning of embryo	Hk2	Hk2^tm1Laak/Hk2^tm1Laak	involves: 129P2/OlaHsd * BALB/c * DBA/2	color key
MP:0006207	embryonic lethality during organogenesis	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0001926	female infertility	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0001585	hemolytic anemia	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0002814	hyperchromasia	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0006042	increased apoptosis	Mpi	Mpi^{Gt(OST90588)Lex}/Mpi^{Gt(OST90588)Lex}	involves: 129S/SvEv * C57BL/6	color key
MP:0005344	increased circulating bilirubin level	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0008807	increased liver iron level	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0002590	increased mean corpuscular volume	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0008476	increased spleen red pulp amount	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0004952	increased spleen weight	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0003718	maternal effect	Pmm2	Pmm2^tm1Cthl/Pmm2^tm1Cthl	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002169	no abnormal phenotype detected	Pmm1	Pmm1^tm1Gmat/Pmm1^tm1Gmat	B6.129-Pmm1	color key
MP:0003717	pallor	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0005097	polychromatophilia	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key
MP:0002640	reticulocytosis	Hk1	Hk1^dea/Hk1^dea	A/J-Hk1/J	color key