MGI MouseCyc MP annotations for HEME-BIOSYNTHESIS-II

MGI MouseCyc experimental MP annotations for heme biosynthesis from uroporphyrinogen I

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for heme biosynthesis from uroporphyrinogen I

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Cpox	Fech	Ppox	Urod
MP:0005375	adipose tissue phenotype	Cpox	Fech	Ppox	Urod
MP:0005386	behavior/neurological phenotype	Cpox	Fech	Ppox	Urod
MP:0005378	growth/size phenotype	Cpox	Fech	Ppox	Urod
MP:0005397	hematopoietic system phenotype	Cpox	Fech	Ppox	Urod
MP:0005376	homeostasis/metabolism phenotype	Cpox	Fech	Ppox	Urod
MP:0005387	immune system phenotype	Cpox	Fech	Ppox	Urod
MP:0005374	lethality-prenatal/perinatal	Cpox	Fech	Ppox	Urod
MP:0005370	liver/biliary system phenotype	Cpox	Fech	Ppox	Urod
MP:0002873	normal phenotype	Cpox	Fech	Ppox	Urod
MP:0005389	reproductive system phenotype	Cpox	Fech	Ppox	Urod
MP:0005393	skin/coat/nails phenotype	Cpox	Fech	Ppox	Urod

Full set of annotations for heme biosynthesis from uroporphyrinogen I

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0001570	abnormal circulating enzyme level	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0003657	abnormal erythrocyte lysis	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0002447	abnormal erythrocyte morphology	Fech	Fech^m1Pas/Fech^m1Pas,hem6/hem6⁺	involves: 129 * BALB/c * C57BL/6	color key
MP:0002447	abnormal erythrocyte morphology	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0000245	abnormal erythropoiesis	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0002642	anisocytosis	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0005454	decreased adipose tissue amount	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0002875	decreased erythrocyte cell number	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0000208	decreased hematocrit	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0002874	decreased hemoglobin content	Fech	Fech^m1Pas/Fech^m1Pas,hem6/hem6⁺	involves: 129 * BALB/c * C57BL/6	color key
MP:0002874	decreased hemoglobin content	Fech	Fech^m1Pas/Fech^m1Pas,hem6/hem6	involves: 129 * BALB/c * C57BL/6	color key
MP:0002874	decreased hemoglobin content	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0001270	distended abdomen	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0006205	embryonic lethality before somite formation	Urod	Urod^tm1Kush/Urod^tm1Kush	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0006206	embryonic lethality before turning of embryo	Fech	Fech^tm1Dab/Fech^tm1Dab	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001402	hypoactivity	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0008387	hypochromic anemia	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0002968	increased circulating alkaline phosphatase level	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0005344	increased circulating bilirubin level	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0008807	increased liver iron level	Urod	Hfe^tm2Nca/Hfe^tm2Nca,Urod^tm1Kush/Urod⁺	involves: C57BL/6J	color key
MP:0002981	increased liver weight	Fech	Fech^m1Pas/Fech^m1Pas,hem6/hem6⁺	involves: 129 * BALB/c * C57BL/6	color key
MP:0002981	increased liver weight	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0004147	increased porphyrin level	Fech	Fech^m1Pas/Fech^m1Pas,hem6/hem6	involves: 129 * BALB/c * C57BL/6	color key
MP:0004147	increased porphyrin level	Fech	Fech^m1Pas/Fech^m1Pas,hem6/hem6⁺	involves: 129 * BALB/c * C57BL/6	color key
MP:0004147	increased porphyrin level	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0004147	increased porphyrin level	Urod	Hfe^tm2Nca/Hfe^tm2Nca,Urod^tm1Kush/Urod⁺	involves: C57BL/6J	color key
MP:0004952	increased spleen weight	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0000611	jaundice	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0002169	no abnormal phenotype detected	Urod	Urod^tm1Kush/Urod⁺	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0005097	polychromatophilia	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0001921	reduced fertility	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0002640	reticulocytosis	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0001202	skin photosensitivity	Fech	Fech^m1Pas/Fech^m1Pas	involves: 129/Sv * BALB/c	color key
MP:0001202	skin photosensitivity	Fech	Fech^tm1Dab/Fech⁺	involves: 129P2/OlaHsd * C57BL/6	color key