MGI MouseCyc MP annotations for CITRULBIO-PWY

MGI MouseCyc experimental MP annotations for citrulline biosynthesis

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for citrulline biosynthesis

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005386	behavior/neurological phenotype	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005378	growth/size phenotype	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005377	hearing/vestibular/ear phenotype	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005397	hematopoietic system phenotype	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005376	homeostasis/metabolism phenotype	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005387	immune system phenotype	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005373	lethality-postnatal	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005374	lethality-prenatal/perinatal	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005372	life span-post-weaning/aging	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005370	liver/biliary system phenotype	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0003631	nervous system phenotype	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0001186	pigmentation phenotype	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005367	renal/urinary system phenotype	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005388	respiratory system phenotype	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005393	skin/coat/nails phenotype	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2
MP:0005391	vision/eye phenotype	Aldh18a1	Arg1	Arg2	Gls	Gls2	Oat	Otc	Prodh	Prodh2

Full set of annotations for citrulline biosynthesis

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0004924	abnormal behavior	Gls	Gls^tm1Sray/Gls^tm1Sray	involves: 129S1/Sv * C57BL/6	color key
MP:0005010	abnormal CD8-positive T cell morphology	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005332	abnormal amino acid level	Prodh	Prodh^m1Kara/Prodh^m1Kara	involves: C57BL/6J * PRO/Re	color key
MP:0005311	abnormal circulating amino acid level	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0005311	abnormal circulating amino acid level	Arg2	Arg2^tm1Weo/Arg2⁺	involves: C57BL/6J	color key
MP:0005311	abnormal circulating amino acid level	Arg2	Arg2^tm1Weo/Arg2^tm1Weo	involves: C57BL/6J	color key
MP:0005311	abnormal circulating amino acid level	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0005311	abnormal circulating amino acid level	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0005311	abnormal circulating amino acid level	Prodh	Prodh^m1Kara/Prodh^m1Kara	involves: C57BL/6J * PRO/Re	color key
MP:0003009	abnormal cytokine secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005551	abnormal eye electrophysiology	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0002073	abnormal hair growth	Otc	Otc^spf/Otc^spf	Not Specified	color key
MP:0000607	abnormal hepatocyte morphology	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0001764	abnormal homeostasis	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0002722	abnormal immune system organ morphology	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002722	abnormal immune system organ morphology	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008751	abnormal interleukin level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000598	abnormal liver morphology	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0002138	abnormal liver/biliary system morphology	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0002339	abnormal lymph node morphology	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002451	abnormal macrophage physiology	Arg1	Arg1^tm1Pmu/Arg1^tm1Pmu,Tg(Tek-cre)1Ywa/?	B6.Cg-Arg1 Tg(Tek-cre)1Ywa	color key
MP:0002451	abnormal macrophage physiology	Arg1	Arg1^tm1.1Pmu/Arg1^tm1.1Pmu	involves: C57BL/6	color key
MP:0003957	abnormal nitric oxide homeostasis	Arg1	Arg1^tm1Pmu/Arg1^tm1Pmu,Tg(Tek-cre)1Ywa/?	B6.Cg-Arg1 Tg(Tek-cre)1Ywa	color key
MP:0003957	abnormal nitric oxide homeostasis	Arg1	Arg1^tm1.1Pmu/Arg1^tm1.1Pmu	involves: C57BL/6	color key
MP:0002327	abnormal respiratory function	Gls	Gls^tm1Sray/Gls^tm1Sray	involves: 129S1/Sv * C57BL/6	color key
MP:0001325	abnormal retina morphology	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0005201	abnormal retinal pigment epithelium morphology	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0005201	abnormal retinal pigment epithelium morphology	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0008752	abnormal tumor necrosis factor level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001757	abnormal urine chemistry	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0008585	absent photoreceptor outer segment	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0001577	anemia	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0001577	anemia	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001265	decreased body size	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001262	decreased body weight	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0001262	decreased body weight	Prodh	Prodh^m1Kara/Prodh^m1Kara	involves: C57BL/6J * PRO/Re	color key
MP:0000208	decreased hematocrit	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000208	decreased hematocrit	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0001327	decreased retinal photoreceptor cell number	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002411	decreased susceptibility to bacterial infection	Arg1	Arg1^tm1Pmu/Arg1^tm1Pmu,Tg(Tek-cre)1Ywa/?	B6.Cg-Arg1 Tg(Tek-cre)1Ywa	color key
MP:0005026	decreased susceptibility to parasitic infection	Arg1	Arg1^tm1Pmu/Arg1^tm1Pmu,Lyz2^tm1(cre)Ifo/?	B6.Cg-Arg1 Lyz2	color key
MP:0000422	delayed hair appearance	Otc	Otc^spf/Otc⁺	Not Specified	color key
MP:0001194	dermatitis	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008581	disorganized photoreceptor inner segment	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0000599	enlarged liver	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0000702	enlarged lymph nodes	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000702	enlarged lymph nodes	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000702	enlarged lymph nodes	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0000691	enlarged spleen	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000691	enlarged spleen	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0008074	increased CD4-positive T cell number	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0005309	increased circulating ammonia level	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0005309	increased circulating ammonia level	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002493	increased IgG level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002494	increased IgM level	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008074	increased CD4-positive T cell number	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002493	increased IgG level	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002494	increased IgM level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002461	increased immunoglobulin level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008699	increased interleukin-4 secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008705	increased interleukin-6 secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008097	increased plasma cell number	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001488	increased startle reflex	Prodh	Prodh^m1Kara/Prodh^m1Kara	involves: C57BL/6J * PRO/Re	color key
MP:0008560	increased tumor necrosis factor secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005202	lethargy	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002058	neonatal lethality	Gls	Gls^tm1Sray/Gls^tm1Sray	involves: 129S1/Sv * C57BL/6	color key
MP:0002058	neonatal lethality	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0000603	pale liver	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0000418	patchy hair	Otc	Otc^spf/Otc^spf	Not Specified	color key
MP:0000418	patchy hair	Otc	Otc^spf/Otc⁺	Not Specified	color key
MP:0002082	postnatal lethality	Arg1	Arg1^tm1.1Pmu/Arg1^tm1.1Pmu	involves: C57BL/6	color key
MP:0002082	postnatal lethality	Arg1	Arg1^tm1Rki/Arg1^tm1Rki	Not Specified	color key
MP:0002082	postnatal lethality	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0002083	premature death	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0002083	premature death	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000424	retarded hair growth	Otc	Otc^spf-ash/Y	Not Specified	color key
MP:0000424	retarded hair growth	Otc	Otc^spf-ash/Otc⁺	Not Specified	color key
MP:0000424	retarded hair growth	Otc	Otc^spf-ash/Otc^spf-ash	Not Specified	color key
MP:0001326	retinal degeneration	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0001326	retinal degeneration	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0008582	short photoreceptor inner segment	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0008587	short photoreceptor outer segment	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001212	skin lesions	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0008515	thin retinal outer nuclear layer	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0001211	wrinkled skin	Otc	Otc^spf-ash/Y	Not Specified	color key
MP:0001211	wrinkled skin	Otc	Otc^spf-ash/Otc^spf-ash	Not Specified	color key