MGI MouseCyc MP annotations for ARGORNPROST-PWY

MGI MouseCyc experimental MP annotations for interconversion of arginine, ornithine and proline (Stickland reaction)

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for interconversion of arginine, ornithine and proline (Stickland reaction)

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005386	behavior/neurological phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005378	growth/size phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005397	hematopoietic system phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005376	homeostasis/metabolism phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005387	immune system phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005373	lethality-postnatal	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005374	lethality-prenatal/perinatal	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005372	life span-post-weaning/aging	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0003631	nervous system phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0001186	pigmentation phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005367	renal/urinary system phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005393	skin/coat/nails phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl
MP:0005391	vision/eye phenotype	Oat	Otc	Pycr1	Pycr2	Pycrl

Full set of annotations for interconversion of arginine, ornithine and proline (Stickland reaction)

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0005010	abnormal CD8-positive T cell morphology	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005311	abnormal circulating amino acid level	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0005311	abnormal circulating amino acid level	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0003009	abnormal cytokine secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005551	abnormal eye electrophysiology	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0002073	abnormal hair growth	Otc	Otc^spf/Otc^spf	Not Specified	color key
MP:0002722	abnormal immune system organ morphology	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002722	abnormal immune system organ morphology	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008751	abnormal interleukin level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002339	abnormal lymph node morphology	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001325	abnormal retina morphology	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0005201	abnormal retinal pigment epithelium morphology	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0005201	abnormal retinal pigment epithelium morphology	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0008752	abnormal tumor necrosis factor level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001757	abnormal urine chemistry	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0008585	absent photoreceptor outer segment	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0001577	anemia	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0001577	anemia	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001265	decreased body size	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001262	decreased body weight	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0000208	decreased hematocrit	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0000208	decreased hematocrit	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0001327	decreased retinal photoreceptor cell number	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0000422	delayed hair appearance	Otc	Otc^spf/Otc⁺	Not Specified	color key
MP:0001194	dermatitis	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008581	disorganized photoreceptor inner segment	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0000702	enlarged lymph nodes	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0000702	enlarged lymph nodes	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000702	enlarged lymph nodes	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000691	enlarged spleen	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000691	enlarged spleen	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0008074	increased CD4-positive T cell number	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0008074	increased CD4-positive T cell number	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005309	increased circulating ammonia level	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002494	increased IgM level	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002493	increased IgG level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002493	increased IgG level	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002494	increased IgM level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0002461	increased immunoglobulin level	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008699	increased interleukin-4 secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008705	increased interleukin-6 secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008097	increased plasma cell number	Otc	B2m^tm1Jae/B2m^tm1Jae,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0008560	increased tumor necrosis factor secretion	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0005202	lethargy	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0002058	neonatal lethality	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0000418	patchy hair	Otc	Otc^spf/Otc⁺	Not Specified	color key
MP:0000418	patchy hair	Otc	Otc^spf/Otc^spf	Not Specified	color key
MP:0002082	postnatal lethality	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0002083	premature death	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0002083	premature death	Otc	Cd4^tm1Litt/Cd4^tm1Litt,Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl * 129S2/SvPas	color key
MP:0000424	retarded hair growth	Otc	Otc^spf-ash/Y	Not Specified	color key
MP:0000424	retarded hair growth	Otc	Otc^spf-ash/Otc⁺	Not Specified	color key
MP:0000424	retarded hair growth	Otc	Otc^spf-ash/Otc^spf-ash	Not Specified	color key
MP:0001326	retinal degeneration	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0001326	retinal degeneration	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0008582	short photoreceptor inner segment	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0008587	short photoreceptor outer segment	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd * C57BL/6J	color key
MP:0001212	skin lesions	Otc	Foxp3^sf/Y,Otc^spf/Y	involves: 129/Rl	color key
MP:0008515	thin retinal outer nuclear layer	Oat	Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd	color key
MP:0001211	wrinkled skin	Otc	Otc^spf-ash/Otc^spf-ash	Not Specified	color key
MP:0001211	wrinkled skin	Otc	Otc^spf-ash/Y	Not Specified	color key