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Symbol
Name
ID

Vcp
valosin containing protein
MGI:99919

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes	Hammertoe	Ankle clonus	Limited knee flexion	Scapular winging	Abnormal pelvic girdle bone morphology	Lumbar hyperlordosis	Back pain	Paget disease of bone
Disease(s) Associated with VCP	Hammertoe	Ankle clonus	Limited knee flexion	Scapular winging	Abnormal pelvic girdle bone morphology	Lumbar hyperlordosis	Back pain	Paget disease of bone
Charcot-Marie-Tooth disease type 2Y
frontotemporal dementia and/or amyotrophic lateral sclerosis 6
inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 1

Mouse Phenotypes		abnormal osteoclast differentiation	increased osteoclast cell number	abnormal limb bone morphology	kyphosis	increased compact bone thickness	decreased trabecular bone connectivity density	decreased bone mass
Availability	Mouse Genotype	abnormal osteoclast differentiation	increased osteoclast cell number	abnormal limb bone morphology	kyphosis	increased compact bone thickness	decreased trabecular bone connectivity density	decreased bone mass
	Vcp^tm1Itl/Vcp^tm1Itl
	Vcp^tm1Itl/Vcp⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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