Symbol
Name
ID

Mecp2
methyl CpG binding protein 2
MGI:99918

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes

Brachycephaly

Micrognathia

Malar flattening

Microcephaly

Secondary microcephaly

Progressive microcephaly

Macrocephaly

Short neck

Clinodactyly of the 5th finger

2-3 toe cutaneous syndactyly

Short foot

Small hand

Wrist flexion contracture

Flexion contracture

Kyphosis

Kyphoscoliosis

Scoliosis

Disease(s) Associated with MECP2

Rett syndrome

severe congenital encephalopathy due to MECP2 mutation

syndromic X-linked intellectual disability Lubs type

X-linked intellectual disability-psychosis-macroorchidism syndrome

Mouse Phenotypes		abnormal jaw morphology	abnormal tooth morphology	malocclusion	kyphosis
Availability	Mouse Genotype	abnormal jaw morphology	abnormal tooth morphology	malocclusion	kyphosis
	Mecp2^tm1.1Bird/Mecp2^tm1.1Bird
	Mecp2^tm1.1Bird/Y
	Mecp2^tm1Hzo/Y
	Mecp2^tm1Pplt/Y
	Mecp2^tm1Pplt/0
	Mecp2^tm1Bird/Y Tg(Nes-cre)1Kln/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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