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Symbol
Name
ID
Mecp2
methyl CpG binding protein 2
MGI:99918
Phenotype annotations related to respiratory system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Recurrent respiratory infections
Apnea
Intermittent hyperventilation
Disease(s) Associated with MECP2
Rett syndrome
syndromic X-linked intellectual disability Lubs type

Mouse Phenotypes
respiratory system phenotype
abnormal respiration
decreased tidal volume
abnormal respiratory function
abnormal breathing pattern
increased pulmonary respiratory rate
tachypnea
apnea
respiratory distress
Availability Mouse Genotype
Mecp2tm1.1Bird/Mecp2tm1.1Bird
Mecp2tm1.1Jtc/Mecp2tm1.1Jtc
Mecp2tm1.1Bird/Mecp2+
Mecp2tm1.1Irsf/Mecp2+
Mecp2tm1.1Jae/Mecp2+
Mecp2tm2Bird/Mecp2+
Mecp2tm1.1Bird/Y
Mecp2tm1.1Irsf/Y
Mecp2tm1.1Jae/Y
Mecp2tm1.1Jtc/Y
Mecp2tm1Bird/Y *
Mecp2tm1Pplt/Y
Mecp2tm2Bird/Y
Mecp2tm1Jae/Y
Chattm2(cre)Lowl/Chat+  (conditional)
*
Chattm2(cre)Lowl/Chat+
Mecp2tm2Bird/Y  (conditional)
Mecp2tm2Bird/Mecp2+
Tg(CAG-cre/Esr1*)5Amc/?  (conditional)
Mecp2tm1Bird/Y
Tg(dlx5a-cre)1Mekk/0  (conditional)
*
Mecp2tm1Bird/Y
Tg(Slc32a1-cre)2.1Hzo/0  (conditional)
Mecp2tm1Jae/Y
Tg(Nes-cre)1Atp/0  (conditional)
Mecp2tm2Bird/Y
Tg(CAG-cre/Esr1*)5Amc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory