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Symbol
Name
ID
Mecp2
methyl CpG binding protein 2
MGI:99918
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abnormality of metabolism/homeostasis
Ketonuria
Increased serum serotonin
Disease(s) Associated with MECP2
autistic disorder
syndromic X-linked intellectual disability Lubs type

Mouse Phenotypes
homeostasis/metabolism phenotype
increased response of heart to induced stress
increased circulating LDL cholesterol level
increased circulating cholesterol level
increased circulating triglyceride level
abnormal body temperature
decreased body temperature
decreased noradrenaline level
decreased serotonin level
increased brain cholesterol level
increased liver triglyceride level
Availability Mouse Genotype
Mecp2tm1.1Bird/Mecp2+
Mecp2tm1.1Bird/Y
Mecp2tm1.1Jae/Y *
Mecp2tm2Bird/Y
Mecp2tm1Jae/Y
Chattm2(cre)Lowl/Chat+  (conditional)
Chattm2(cre)Lowl/Chat+
Mecp2tm2Bird/Y  (conditional)
*
Mecp2tm1Jae/Y
Tg(Myh6-cre)2182Mds/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory