Symbol
Name
ID

Mecp2
methyl CpG binding protein 2
MGI:99918

Phenotype annotations related to craniofacial

Darker colors indicate more annotations

Human Phenotypes

Brachycephaly

Micrognathia

Malar flattening

Microcephaly

Secondary microcephaly

Progressive microcephaly

Macrocephaly

Midface retrusion

Facial hypotonia

Tented upper lip vermilion

Thin upper lip vermilion

High palate

Narrow mouth

Abnormality of the dentition

Widely spaced teeth

Excessive salivation

Drooling

Anteverted nares

Bulbous nose

Depressed nasal bridge

Prominent nasal bridge

Wide nasal bridge

Upslanted palpebral fissure

Epicanthus

Disease(s) Associated with MECP2

Rett syndrome

severe congenital encephalopathy due to MECP2 mutation

syndromic X-linked intellectual disability Lubs type

X-linked intellectual disability-psychosis-macroorchidism syndrome

Mouse Phenotypes		abnormal jaw morphology	abnormal tooth morphology	malocclusion
Availability	Mouse Genotype	abnormal jaw morphology	abnormal tooth morphology	malocclusion
	Mecp2^tm1.1Bird/Mecp2^tm1.1Bird
	Mecp2^tm1.1Bird/Y
	Mecp2^tm1Pplt/Y
	Mecp2^tm1Pplt/0
	Mecp2^tm1Bird/Y Tg(Nes-cre)1Kln/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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