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Symbol
Name
ID
Mecp2
methyl CpG binding protein 2
MGI:99918
Phenotype annotations related to craniofacial
Darker colors indicate more annotations
Human Phenotypes
Micrognathia
Malar flattening
Microcephaly
Postnatal microcephaly
Progressive microcephaly
Macrocephaly
Brachycephaly
Disturbance of facial expression
Facial hypotonia
Pointed chin
Midface retrusion
Tented upper lip vermilion
High palate
Narrow mouth
Abnormality of the dentition
Excessive salivation
Drooling
Wide nose
Depressed nasal bridge
Downslanted palpebral fissures
Prominent supraorbital ridges
Disease(s) Associated with MECP2
autistic disorder
Rett syndrome
syndromic X-linked intellectual disability Lubs type
X-linked intellectual disability-psychosis-macroorchidism syndrome

Mouse Phenotypes
abnormal jaw morphology
abnormal tooth morphology
malocclusion
Availability Mouse Genotype
Mecp2tm1.1Bird/Mecp2tm1.1Bird
Mecp2tm1.1Bird/Y
Mecp2tm1Pplt/Y
Mecp2tm1Pplt/0
Mecp2tm1Bird/Y
Tg(Nes-cre)1Kln/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory