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Symbol
Name
ID
Mecp2
methyl CpG binding protein 2
MGI:99918
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Prolonged QTc interval
Abnormal T-wave
Congestive heart failure
Stroke
Disease(s) Associated with MECP2
Rett syndrome
X-linked intellectual disability-psychosis-macroorchidism syndrome

Mouse Phenotypes
cardiovascular system phenotype
increased heart weight
abnormal heartbeat
abnormal heart rate
increased heart rate variability
decreased heart rate
ventricular tachycardia
irregular heartbeat
ventricular premature beat
atrioventricular block
prolonged QT interval
increased response of heart to induced stress
Availability Mouse Genotype
Mecp2tm1.1Bird/Mecp2+
Mecp2tm1.1Irsf/Mecp2+
Mecp2tm1.1Bird/Y
Mecp2tm1.1Irsf/Y
Mecp2tm2Bird/Y
Mecp2tm1Jae/Y
Chattm2(cre)Lowl/Chat+  (conditional)
Chattm2(cre)Lowl/Chat+
Mecp2tm2Bird/Y  (conditional)
*
Mecp2tm1Jae/Y
Tg(Myh6-cre)2182Mds/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory