Symbol Name ID |
Lama2
laminin, alpha 2 MGI:99912 |
Darker colors indicate more annotations |
Human Phenotypes | Facial palsy |
Macroglossia |
Scapular winging |
Shoulder girdle muscle weakness |
Limb-girdle muscular dystrophy |
Myositis |
Flexion contracture |
Hypotonia |
Neonatal hypotonia |
EMG abnormality |
Muscle weakness |
Intercostal muscle weakness |
Respiratory insufficiency due to muscle weakness |
Myotonia |
Absent muscle fiber merosin |
Central core regions in muscle fibers |
Increased endomysial connective tissue |
Muscle fiber atrophy |
Muscular dystrophy |
Myopathy |
Disease(s) Associated with LAMA2 | ||||||||||||||||||||
congenital merosin-deficient muscular dystrophy 1A | ||||||||||||||||||||
muscular dystrophy |
Mouse Phenotypes | opisthotonus |
skeletal muscle fiber necrosis |
myositis |
abnormal sarcolemma morphology |
abnormal skeletal muscle fiber morphology |
increased variability of skeletal muscle fiber size |
centrally nucleated skeletal muscle fibers |
decreased skeletal muscle fiber number |
abnormal skeletal muscle morphology |
skeletal muscle endomysial fibrosis |
skeletal muscle interstitial fibrosis |
dystrophic muscle |
muscle degeneration |
abnormal muscle physiology |
enhanced skeletal muscle regeneration |
impaired skeletal muscle regeneration |
muscle spasm |
muscle weakness |
progressive muscle weakness |
myopathy |
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Availability | Mouse Genotype | ||||||||||||||||||||
Lama2dy-2J/Lama2dy-2J | |||||||||||||||||||||
Lama2dy-6J/Lama2dy-6J | |||||||||||||||||||||
Lama2dy-7J/Lama2dy-7J | |||||||||||||||||||||
Lama2dy-8J/Lama2dy-8J | |||||||||||||||||||||
Lama2dy-Pas/Lama2dy-Pas | |||||||||||||||||||||
Lama2dy/Lama2dy | |||||||||||||||||||||
Lama2tm1Eeng/Lama2tm1Eeng | |||||||||||||||||||||
Lama2tm1Stk/Lama2tm1Stk |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/19/2024 MGI 6.23 |
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