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Symbol
Name
ID
Gcgr
glucagon receptor
MGI:99572
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Type II diabetes mellitus
Insulin resistance
Disease(s) Associated with GCGR
type 2 diabetes mellitus

Mouse Phenotypes
homeostasis/metabolism phenotype
increased glucagon secretion
decreased susceptibility to diet-induced obesity
decreased circulating glucose level
hypoglycemia
increased circulating glucagon level
decreased circulating insulin level
decreased circulating leptin level
increased circulating LDL cholesterol level
decreased carbon dioxide production
decreased oxygen consumption
abnormal glucose homeostasis
improved glucose tolerance
increased insulin sensitivity
increased bile salt level
decreased triglyceride level
decreased susceptibility to diet-induced non-insulin dependent diabetes
Availability Mouse Genotype
Gcgrtm1Jcp/Gcgrtm1Jcp *
Gcgrtm1Mjch/Gcgrtm1Mjch
Gcgrtm2.1Mjch/Gcgrtm2.1Mjch
Tg(Alb-cre)21Mgn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/07/2017
MGI 6.11
The Jackson Laboratory