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Symbol
Name
ID
Gcgr
glucagon receptor
MGI:99572
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Type II diabetes mellitus
Disease(s) Associated with GCGR
type 2 diabetes mellitus

Mouse Phenotypes
abnormal pancreatic alpha cell differentiation
increased pancreatic beta cell proliferation
abnormal pancreatic acinar cell morphology
abnormal pancreatic islet morphology
abnormal pancreatic alpha cell morphology
increased pancreatic alpha cell number
abnormal pancreatic beta cell morphology
enlarged pancreatic islets
pancreatic islet hyperplasia
abnormal exocrine gland morphology
increased pancreas weight
enlarged pancreas
increased pancreas tumor incidence
increased glucagonoma incidence
abnormal pancreatic alpha cell physiology
increased glucagon secretion
Availability Mouse Genotype
Gcgrtm1Jcp/Gcgrtm1Jcp
Gcgrtm1Mjch/Gcgrtm1Mjch
Gcgrtm2.1Mjch/Gcgrtm2.1Mjch
Tg(Alb-cre)21Mgn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory