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Symbol
Name
ID
S1pr2
sphingosine-1-phosphate receptor 2
MGI:99569
Phenotype annotations related to hearing/vestibular/ear
Darker colors indicate more annotations
Human Phenotypes
Sensorineural hearing impairment
Disease(s) Associated with S1PR2
autosomal recessive nonsyndromic deafness 68

Mouse Phenotypes
abnormal stria vascularis vasculature morphology
otosclerosis
detached Reissner membrane
abnormal Rosenthal canal morphology
cochlear outer hair cell degeneration
cochlear hair cell degeneration
organ of Corti degeneration
abnormal stria vascularis morphology
abnormal strial basal cell morphology
abnormal strial intermediate cell morphology
abnormal strial marginal cell morphology
thin stria vascularis
abnormal tectorial membrane morphology
small scala media
vestibular saccular degeneration
abnormal vestibular labyrinth morphology
decreased otolith number
enlarged otoliths
increased or absent threshold for auditory brainstem response
absent distortion product otoacoustic emissions
deafness
abnormal vestibular system physiology
Availability Mouse Genotype
S1pr2tm1Ajml/S1pr2tm1Ajml
S1pr2tm1Rlp/S1pr2tm1Rlp

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/12/2019
MGI 6.13
The Jackson Laboratory