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Symbol
Name
ID
Ptpn11
protein tyrosine phosphatase, non-receptor type 11
MGI:99511
Phenotype annotations related to mortality/aging
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations

Mouse Phenotypes
mortality/aging
decreased survivor rate
premature death
lethality throughout fetal growth and development, complete penetrance
perinatal lethality, incomplete penetrance
embryonic lethality
embryonic lethality during organogenesis, complete penetrance
embryonic lethality during organogenesis, incomplete penetrance
embryonic lethality at implantation, incomplete penetrance
embryonic lethality between implantation and somite formation, complete penetrance
embryonic lethality, complete penetrance
preweaning lethality, complete penetrance
Availability Mouse Genotype
Ptpn11tm1Bgn/Ptpn11tm1Bgn
Ptpn11tm1Paw/Ptpn11tm1Paw
Ptpn11tm1Rbn/Ptpn11tm1Rbn
Ptpn11tm2Bgn/Ptpn11tm2Bgn
Ptpn11tm5Bgn/Ptpn11tm5Bgn
Ptpn11tm7Bgn/Ptpn11tm7Bgn
Ptpn11tm1Bgn/Ptpn11+ *! !
Ptpn11tm4.2Bgn/Ptpn11+
Ptpn11tm1.1Rbns/Ptpn11tm1.1Rbns
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Ptpn11tm1.1Wbm/Ptpn11tm1.1Wbm
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Ptpn11tm1Gsf/Ptpn11tm1Gsf
Tg(Ckmm-cre)5Khn/0  (conditional)
Cd19tm1(cre)Cgn/Cd19+
Ptpn11tm1Ckq/Ptpn11+  (conditional)
Hprt1tm1(CAG-cre)Mnn/Hprt1+
Ptpn11tm1Ckq/Ptpn11+  (conditional)
Ptpn11tm1Ckq/Ptpn11+
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)
Ptpn11tm1Ckq/Ptpn11+
Tg(Mx1-cre)1Cgn/0  (conditional)
Ptpn11tm1Ckq/Ptpn11+
Tg(Lck-cre)1Cwi/0  (conditional)
Ptpn11tm6Bgn/Ptpn11+
Tg(Tek-cre)12Flv/0  (conditional)
Ptpn11tm6Bgn/Ptpn11+
Tg(Mx1-cre)1Cgn/0  (conditional)
Ptpn11tm6Bgn/Ptpn11+
Tg(EIIa-cre)C5379Lmgd/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory