About   Help   FAQ
Symbol
Name
ID
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
MGI:99400
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Decreased circulating copper concentration
Decreased circulating ceruloplasmin concentration
Hypothermia
Atypical scarring of skin
Keloids
Scarring
Cerebral calcification
Disease(s) Associated with ATP7A
Menkes disease
occipital horn syndrome

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased creatine level
decreased circulating copper level
decreased circulating ceruloplasmin level
abnormal noradrenaline level
decreased noradrenaline level
abnormal ion homeostasis
abnormal copper homeostasis
abnormal copper level
decreased brainstem copper level
decreased brain copper level
increased brain copper level
increased intestine copper level
increased kidney copper level
abnormal liver copper level
decreased liver copper level
abnormal pH regulation
abnormal enzyme/coenzyme activity
decreased creatine kinase activity
Availability Mouse Genotype
Atp7aMo-blo/Atp7a+
Atp7aMo-brJ/Atp7a+ *
Atp7aMo-dp/Atp7a+
Atp7aMo-ml/Atp7a+
Atp7aMo-to/Atp7a+
Atp7aMo-Tohm/Atp7a+
Atp7aMo-3Btlr/Y
Atp7aMo-blo/Y
Atp7aMo-br/Y
Atp7aMo-brJ/Y
Atp7aMo-ml/Y *
Atp7aMo-ms/Y
Atp7aMo-Tohm/Y
Atp7aMo-vbr/Y *
Atp7atm1.2Mlke/Y
Atp7aMo-blo/?
Atp7atm1.1Mjp/Y
Mnx1tm4(cre)Tmj/Mnx1+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory