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Symbol
Name
ID
Fasl
Fas ligand
MGI:99255
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abnormal lymphocyte apoptosis
Decreased lymphocyte apoptosis
Increased circulating IgA level
Increased circulating IgE level
Decreased circulating IgG level
Increased circulating IgG level
Decreased circulating total IgM
Increased circulating IgM level
Decreased specific anti-polysaccharide antibody level
Increased circulating antibody level
Reduced delayed hypersensitivity
Elevated circulating creatinine concentration
Elevated circulating hepatic transaminase concentration
Reduced leukocyte alkaline phosphatase
Diabetes mellitus
Type I diabetes mellitus
Type II diabetes mellitus
Insulin resistance
Edema
Hydrops fetalis
Pulmonary edema
Fever
Abnormal circulating vitamin B12 concentration
Proteinuria
Disease(s) Associated with FASLG
autoimmune lymphoproliferative syndrome
chronic myeloid leukemia
pancreatic cancer
pre-eclampsia
type 2 diabetes mellitus

Mouse Phenotypes
homeostasis/metabolism phenotype
increased circulating tumor necrosis factor level
decreased circulating alanine transaminase level
skin edema
abnormal interleukin level
increased urine protein level
decreased susceptibility to injury
Availability Mouse Genotype
Faslgld/Faslgld *
Fasltm1.1Ast/Fasltm1.1Ast
Fasltm1.1Lest/Fasltm1.1Lest

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory