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Symbol
Name
ID
Fasl
Fas ligand (TNF superfamily, member 6)
MGI:99255
Phenotype annotations related to cellular
Darker colors indicate more annotations
Human Phenotypes
Decreased lymphocyte apoptosis
Increased circulating IgA level
Increased circulating total IgE level
Decreased circulating IgG level
Increased circulating IgG level
Decreased circulating total IgM
Increased circulating IgM level
Specific anti-polysaccharide antibody deficiency
Increased antibody level in blood
Reduced delayed hypersensitivity
Disease(s) Associated with FASLG
autoimmune lymphoproliferative syndrome

Mouse Phenotypes
decreased neuron apoptosis
increased retinal apoptosis
decreased hepatocyte apoptosis
increased apoptosis
focal hepatic necrosis
increased B cell proliferation
abnormal T cell proliferation
increased T cell proliferation
impaired macrophage phagocytosis
Availability Mouse Genotype
Faslgld/Faslgld
Fasltm1.1Cgm/Fasltm1.1Cgm
Fasltm2.1Bksa/Fasltm2.1Bksa

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory