Symbol Name ID |
Xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1 MGI:99137 |
Darker colors indicate more annotations |
Human Phenotypes | Increased LDL cholesterol concentration |
Hypercholesterolemia |
Hypertriglyceridemia |
Elevated circulating hepatic transaminase concentration |
Reduced leukocyte alkaline phosphatase |
Glucose intolerance |
Diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Insulin resistance |
Fever |
Increased level of L-fucose in urine |
Disease(s) Associated with XRCC1 | ||||||||||||
chronic myeloid leukemia | ||||||||||||
coronary artery disease | ||||||||||||
pancreatic cancer | ||||||||||||
stomach cancer | ||||||||||||
type 2 diabetes mellitus |
Mouse Phenotypes | abnormal DNA repair |
decreased catalase activity |
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Availability | Mouse Genotype | ||
Xrcc1tm1Pmc/Xrcc1tm1Pmc Tg(Nes-cre)1Kln/0 (conditional) |
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Alpltm1(cre)Nagy/Alpl+ Xrcc1tm1Pmc/Xrcc1tm1Pmc (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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