Symbol Name ID |
Wnt3
wingless-type MMTV integration site family, member 3 MGI:98955 |
Darker colors indicate more annotations |
Human Phenotypes | Single umbilical artery |
Disease(s) Associated with WNT3 | |
tetraamelia syndrome 1 |
Mouse Phenotypes | increased ectoderm apoptosis |
abnormal germ layer development |
abnormal ectoderm development |
failure to gastrulate |
abnormal rostral-caudal axis patterning |
abnormal embryo size |
abnormal embryonic epiblast morphology |
abnormal apical ectodermal ridge morphology |
thin apical ectodermal ridge |
absent mesoderm |
absent primitive node |
failure of primitive streak formation |
disorganized embryonic tissue |
abnormal extraembryonic tissue morphology |
absent allantois |
absent amnion |
absent amniotic folds |
absent chorion |
absent visceral yolk sac |
abnormal extraembryonic endoderm formation |
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Availability | Mouse Genotype | ||||||||||||||||||||
Wnt3tm1Amc/Wnt3tm1Amc | |||||||||||||||||||||
Wnt3tm1Brd/Wnt3tm1Brd | |||||||||||||||||||||
Wnt3tm1Amc/Wnt3tm2Amc Tg(Msx2-cre)5Rem/0 (conditional) |
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Wnt3tm1Amc/Wnt3tm2Amc Tg(Rarb-cre)1Mrc/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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