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Symbol
Name
ID
Wnt3
wingless-type MMTV integration site family, member 3
MGI:98955
Phenotype annotations related to embryo
Darker colors indicate more annotations
Human Phenotypes
Single umbilical artery
Disease(s) Associated with WNT3
tetraamelia syndrome 1

Mouse Phenotypes
increased ectoderm apoptosis
abnormal germ layer development
abnormal ectoderm development
failure to gastrulate
abnormal rostral-caudal axis patterning
abnormal embryo size
abnormal embryonic epiblast morphology
abnormal apical ectodermal ridge morphology
thin apical ectodermal ridge
absent mesoderm
absent primitive node
failure of primitive streak formation
disorganized embryonic tissue
abnormal extraembryonic tissue morphology
absent allantois
absent amnion
absent amniotic folds
absent chorion
absent visceral yolk sac
abnormal extraembryonic endoderm formation
Availability Mouse Genotype
Wnt3tm1Amc/Wnt3tm1Amc
Wnt3tm1Brd/Wnt3tm1Brd
Wnt3tm1Amc/Wnt3tm2Amc
Tg(Msx2-cre)5Rem/0  (conditional)
Wnt3tm1Amc/Wnt3tm2Amc
Tg(Rarb-cre)1Mrc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory