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Symbol
Name
ID
Vwf
Von Willebrand factor
MGI:98941
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Macroscopic hematuria
Decreased level of D-mannose in urine
Disease(s) Associated with VWF
Behcet's disease
Bernard-Soulier syndrome

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased myocardial infarct size
abnormal platelet physiology
abnormal platelet activation
abnormal platelet aggregation
decreased platelet aggregation
abnormal blood coagulation
increased partial thromboplastin time
decreased susceptibility to induced thrombosis
impaired blood coagulation
increased bleeding time
abnormal response to injury
decreased susceptibility to ischemic brain injury
Availability Mouse Genotype
Vwftm1.1Diac/Vwftm1.1Diac
Vwftm1.1Geno/Vwftm1.1Geno
Vwftm1.1Vhf/Vwftm1.1Vhf
Vwftm1Wgr/Vwftm1Wgr
Vwftm2.1Diac/Vwftm2.1Diac *
Vwftm1.1Geno/Vwf+
Vwftm1.1Vhf/Vwf+
Vwftm1Wgr/Vwf+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory