About   Help   FAQ
Symbol
Name
ID
Twist1
twist basic helix-loop-helix transcription factor 1
MGI:98872
Phenotype annotations related to craniofacial
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Facial asymmetry
Flat face
Cleft of chin
Low anterior hairline
Flat forehead
Frontal bossing
High forehead
Prominent forehead
Malar flattening
Midface retrusion
Increased number of teeth
Dental malocclusion
Cleft palate
Cleft soft palate
High palate
Narrow palate
Anteverted nares
Long nose
Narrow nose
Short nose
Convex nasal ridge
Downslanted palpebral fissures
Telecanthus
Abnormality of the nasolacrimal system
Shallow orbits
Hypertelorism
Hypotelorism
Micrognathia
Retrognathia
Hypoplasia of the maxilla
Microcephaly
Macrocephaly
Flat occiput
Parietal foramina
Brachycephaly
Brachyturricephaly
Craniosynostosis
Coronal craniosynostosis
Bicoronal synostosis
Unicoronal synostosis
Lambdoidal craniosynostosis
Pansynostosis
Dolichocephaly
Scaphocephaly
Plagiocephaly
Anterior plagiocephaly
Posterior plagiocephaly
Skull asymmetry
Trigonocephaly
Turricephaly
Oxycephaly
Delayed cranial suture closure
Wide anterior fontanel
Disease(s) Associated with TWIST1
craniosynostosis
Saethre-Chotzen syndrome

Mouse Phenotypes
craniofacial phenotype
enlarged interparietal bone
abnormal temporal bone morphology
short squamosal bone
cleft palate
Availability Mouse Genotype
Twist1Pas/Twist1+
Twist1tm1Bhr/Twist1+ *
Twist1tm1Bhr/Twist1tm2Bhr

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/14/2017
MGI 6.11
The Jackson Laboratory